Paul Webb, PhD

Full Affiliate Member, Research Institute
Houston Methodist

Former affiliations

Professor of Genomic Medicine, Academic Institute
Department of Medicine
Weill Cornell Medical College

12132 Citations
51 h-Index

Research output per year

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Personal profile

After completion of his fellowship in the Metabolic Research Unit at the University of California at San Francisco (UCSF) in 1994, Dr. Webb joined the permanent research staff there in the laboratory of Dr. John Baxter. He rose through the ranks and, in 1999, became an Assistant Research Biochemist Level IV. In 2001, Dr. Webb joined the Diabetes Center at UCSF where he was quickly promoted to an Associate Researcher Level IV. He spent a year as a visiting professor in Biochemistry at the University of San Francisco in 2005 where he taught several courses in biochemistry. He has co-written over 130 manuscripts that have been published in peer-reviewed publications.

Research interests

Dr. Webb's main research interests are investigations into the principles of nuclear hormone receptor structure and function, as well as studies of the actions of pharmaceutical agents to selectively modulate actions of these proteins. Research approaches include X-ray structural analysis, targeted mutagenesis to understand receptor structure, detailed analysis of gene expression and genome wide sequence interactions and collaborative studies to determine the metabolic effects of drugs in preclinical models.

Education/Academic qualification

Postdoctoral Fellowship, Immunology Department, University of California, San Francisco, CA

Biochemistry & Molecular Biology, PhD, Imperial Cancer Research Fund, London University, London

Postdoctoral Fellowship, Metabolic Research Unit, University of California, San Francisco, CA

Biochemistry, MA, Pembroke College, Oxford University

Free-text keywords

Diabetes
Nuclear hormone receptor
Ligand design

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Projects

10 Finished

itNETZ: Integrative and Translational Network-based Cellular Signature Analyzer

Li, F. & Webb, P.

National Heart Lung and Blood Institute

9/24/11 → 4/12/13

Project: Federal Funding Agencies

Structural Basis of AR and NR Repression Mechanisms in Prostate Cancer

Webb, P.

Cancer Prevention and Res Inst of Texas

7/1/11 → 12/30/16

Project: State

Salary agreement

Webb, P.

University of Houston

4/18/11 → 1/31/14

Project: Non Profit

Optimal Selective Thyroid Hormone Analogs for Metabolic Syndrome

Webb, P. & Shi, Z.

9/30/10 → 8/31/13

Project: Federal Funding Agencies

Structures of Protein Complexes Regulating Transcription in Embryonic Stem Cells

Webb, P.

University of California San Francisco

9/30/10 → 6/30/15

Project: Federal Funding Agencies