Personal profile

After finishing all seven of her postdoctoral training programs, Dr. Chévez-Barrios joined the faculty of the Baylor College of Medicine in 1996 as an Assistant Professor in the Department of Pathology, with a secondary appointment in the Department of Ophthalmology. She became a Clinical Assistant Professor in the Department of Ophthalmology there in 2004, and received the Fulbright & Jaworski LLP Award for Faculty Excellence in Teaching and Evaluation and became Associate Member of the Cell and Gene Therapy Center that same year. She has current appointments of adjunct professor in the Department of Pathology at The University of Texas MD Anderson Cancer Center and Department of Ophthalmology at the Baylor College of Medicine. Dr. Chévez- Barrios assumed her current positions at Methodist in 2004.

Research interests

The main research interest of Dr. Chévez-Barrios and her laboratory is the study of retinoblastoma, including cancer stem cells, suicide gene therapy for retinoblastoma, the study of metastatic properties of retinoblastoma and preclinical models of the tumor. Other topics of interest are ocular gene therapy, cataractogenesis, vascular proliferation in hypoxic ocular diseases and corneal diseases. Dr. Chevez-Barrios’ laboratory is currently participating in the project of gene therapy for Retinoblastomas in collaboration with the Texas Children’s Cancer Center and the Center for Gene Therapy of Texas Children's Hospital, and Baylor College of Medicine. Pre-clinical studies and a phase 1 clinical trial of vitreous seed of retinoblastoma have been completed. The phase II clinical trial is in preparation. Dr. Chevez-Barrios is a committee member responsible of evaluating all enucleated eyes from the prospective multicenter study of the ARET0332 Children’s Oncology Group protocol on “A Study of Unilateral Retinoblastoma With and Without Histopathologic High-Risk Features and the Role of Adjuvant Chemotherapy. Dr. Chevez-Barrios is also interested in the biological differences between retinoblastoma cell lines that have the capability of producing metastasis, and those that behave less aggressively and remain as intraocular tumors.

Keywords

    Research Area Keywords

  • Cancer

    Free-text keywords

  • Retinoblastoma, Metastasis, Gene therapy, Neovascularization

Fingerprint

Retinoblastoma
Concept: Retinoblastoma
Weight: 100%
Domain: Medicine & Life Sciences
Neoplasms
Concept: Neoplasms
Weight: 30%
Domain: Medicine & Life Sciences
Biopsy
Concept: Biopsy
Weight: 17%
Domain: Medicine & Life Sciences
Retina
Concept: Retina
Weight: 15%
Domain: Medicine & Life Sciences
Rabbits
Concept: Rabbits
Weight: 14%
Domain: Medicine & Life Sciences
Eye Enucleation
Concept: Eye Enucleation
Weight: 14%
Domain: Medicine & Life Sciences
Retinal Neoplasms
Concept: Retinal Neoplasms
Weight: 14%
Domain: Medicine & Life Sciences
Intraocular Lymphoma
Concept: Intraocular Lymphoma
Weight: 14%
Domain: Medicine & Life Sciences
Pathology
Concept: Pathology
Weight: 13%
Domain: Medicine & Life Sciences
Therapeutics
Concept: Therapeutics
Weight: 13%
Domain: Medicine & Life Sciences
Research OutputsResearch Output authored by Patricia Chévez-Barrios is tagged with the concept

Journals

Archives of Pathology and Laboratory Medicine

ISSNs: 0003-9985, 1543-2165, 0363-0153

Additional searchable ISSN (Electronic): 1543-2165

College of American Pathologists

Journal

12

Investigative Ophthalmology and Visual Science

ISSNs: 0146-0404

Association for Research in Vision and Ophthalmology Inc.

Journal

8

Archives of Ophthalmology

ISSNs: 0003-9950

American Medical Association

Journal

7

Plastic and reconstructive surgery

ISSNs: 0032-1052, 0740-9303

Additional searchable ISSN (Electronic): 1529-4242

Lippincott Williams and Wilkins

Journal

7

Ophthalmology

ISSNs: 0161-6420

Elsevier

Journal

7
has published Research OutputsResearch Output by Patricia Chévez-Barrios

Research Network

Visualization: Institutional Network

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Patricia Chévez-Barrios

Visualization: Co-author Network

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Patricia Chévez-Barrios

Shared Pub. Internal Organizations

18
17

Neurosciences Research Program

Organizational unit: Programs

12

Neurological Institute

Organizational unit: Centers of Excellence

11

J.C. Walter Jr. Transplant Center

Organizational unit: Centers of Excellence

4
has Research OutputsResearch Output by Patricia Chévez-Barrios

Shared Pub. External Organizations

Baylor College of Medicine

External organization: Unknown

36

Houston Methodist Research Institute

External organization: Unknown

19

Cullen Eye Institute

External organization: Unknown

12

University of Southern California School of Medicine

External organization: Unknown

7

Baylor College of Medicine

External organization: Unknown

6
has Research OutputsResearch Output by Patricia Chévez-Barrios

Shared Pub. Internal co-authors

has co-authored Research OutputsResearch Output with Patricia Chévez-Barrios

Shared Pub. External co-authors

Mary Y. Hurwitz

External person

14

Ramon L. Font

External person

6

Evelyn A. Paysse

External person

5

Jonathan W. Kim

External person

5

Carlos Rodriguez-Galindo

External person

4
has co-authored Research OutputsResearch Output with Patricia Chévez-Barrios

ID: 2286439