Personal profile

Neal Copeland received his Ph.D. in Biochemistry from the University of Utah. Following postdoctoral studies at Harvard Medical School, he joined the staff of The Jackson Laboratory and then the National Cancer Institute-Frederick, where he was Director of the Mammalian Genetics Laboratory, the forerunner of the Mouse Cancer Genetics Program that he also directed. He moved to the Institute of Molecular and Cell Biology in Singapore in 2006, where he served as the Executive Director for most of his stay. In 2011 he returned to the US to serve as Director of the Houston Methodist Cancer Biology Program at Houston Methodist Research Institute. For more than 30 years he has co-headed a laboratory with Nancy Jenkins. The focus of their current research is cancer genetics. They have co-authored more than 800 papers and are among the most cited biomedical research scientists in the world today. Both have served on numerous scientific advisory and editorial boards and they have consulted for several biotechnology and pharmaceutical companies. Both are also members of the US National Academy of Sciences.

Research interests

Jenkins and Copeland have modeled many different types of human disease in the mouse, but the focus of their current research is exclusively cancer. They are using the Sleeping Beauty transposable element system to tag and clone genes involved in the initiation, progression and metastasis of cancer. It is hoped that a better understanding of the genetics of cancer will lead to the development of additional targeted therapies for the treatment of various forms of the disease.

Keywords

    Research Area Keywords

  • Cancer

    Free-text keywords

  • Mouse models of cancer, Insertional mutagenesis, Forward genetic screens, High throughput sequencing, Candidate cancer gene detection

Fingerprint

Genes
Concept: Genes
Weight: 100%
Domain: Chemical Compounds
Chromosomes
Concept: Chromosomes
Weight: 41%
Domain: Chemical Compounds
Cloning
Concept: Cloning
Weight: 41%
Domain: Chemical Compounds
Complementary DNA
Concept: Complementary DNA
Weight: 23%
Domain: Chemical Compounds
Proteins
Concept: Proteins
Weight: 21%
Domain: Chemical Compounds
Cells
Concept: Cells
Weight: 21%
Domain: Chemical Compounds
Tissue
Concept: Tissue
Weight: 18%
Domain: Chemical Compounds
Mutagenesis
Concept: Mutagenesis
Weight: 17%
Domain: Chemical Compounds
Stem cells
Concept: Stem cells
Weight: 14%
Domain: Chemical Compounds
Viruses
Concept: Viruses
Weight: 14%
Domain: Chemical Compounds
Research OutputsResearch Output authored by Neal G. Copeland is tagged with the concept

Journals

Genomics

ISSNs: 0888-7543

Academic Press

Journal

171

Proceedings of the National Academy of Sciences of the United States of America

ISSNs: 0027-8424

Journal

51

Mammalian Genome

ISSNs: 0938-8990

Springer New York

Journal

42

The Journal of biological chemistry

ISSNs: 0021-9258

American Society for Biochemistry and Molecular Biology Inc.

Journal

38

Journal of Virology

ISSNs: 0022-538X

American Society for Microbiology

Journal

31
has published Research OutputsResearch Output by Neal G. Copeland

Research Network

Visualization: Institutional Network

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Neal G. Copeland

Visualization: Co-author Network

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Neal G. Copeland

Shared Pub. Internal Organizations

Department of Nanomedicine

Organizational unit: Departments

6
has Research OutputsResearch Output by Neal G. Copeland

Shared Pub. External Organizations

Bldg. 539

External organization: Unknown

469

Johns Hopkins University School of Medicine

External organization: Unknown

33

Immunex Corp.

External organization: Unknown

31

Jackson Laboratory

External organization: Government

28

St. Jude Children's Research Hospital

External organization: Unknown

23
has Research OutputsResearch Output by Neal G. Copeland

Shared Pub. Internal co-authors

has co-authored Research OutputsResearch Output with Neal G. Copeland

Shared Pub. External co-authors

Debra J. Gilbert

External person

332

David A. Largaespada

External person

32

Camilynn I. Brannan

External person

31

Eiríkur Steingrímsson

External person

27

David R. Borchelt

External person

24
has co-authored Research OutputsResearch Output with Neal G. Copeland

ID: 2286548