Research output per year
Research output per year
Personal profile
Personal profile
Dr. Kumaraswami received his Ph.D. in microbiology and immunology from the University of Tennessee Health Sciences Center in Memphis. He then completed a postdoctoral fellowship at The University of Texas M.D. Anderson Cancer Center in Houston, Texas. In 2008, Dr. Kumaraswami received the Amgen Award for Basic Science Research from the M.D. Anderson Alumni and Faculty Association. He joined the Center for Molecular and Translational Human Infectious Diseases Research at The Methodist Hospital Research Institute in 2010.
Research interests
Dr. Kumaraswami conducts translational research on the gene regulatory and drug-binding mechanisms of transcription regulators in bacterial pathogens such as Staphylococcus aureus. His research focuses on three major proteins (RopB, RofA, and RocA) that are involved in the coordinated regulation of virulence gene expression and group A streptococci pathogenesis.
Education/Academic qualification
Veterinary Sciences, BVSc, Tamilnadu Veterinary and Animal Sciences, Chennai
Microbial Genetics and Structural Biology, PhD, University of Tennessee Health Science Center
Structural Biology, Postdoctoral Fellowship, University of Texas MD Anderson Cancer Center
Research Area Keywords
- Infectious Disease & Pathology
Free-text keywords
- GAS pathogenesis
- Staphylococcus Aureus
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Collaborations and top research areas from the last five years
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From lab to law: emerging applications, potential benefits, evolving regulatory framework and challenges for engineered probiotics
Di Pierro, F., Thacharodi, A., Kumaraswami, M., Suvorov, A., Zupet, J. & Zerbinati, N., Apr 13 2026, In: Microbial cell factories. 25, 1, 133.Research output: Contribution to journal › Review article › peer-review
Open Access2 Link opens in a new tab Scopus citations -
A zinc-free alternative ribosomal protein RpsN.2 confers survival advantage to group A streptococcus during Zn scarcity
Saha, S., Thacharodi, A., Nguyen, D. L., Makthal, N., Bernard, C. & Kumaraswami, M., Dec 2025, In: Infection and Immunity. 93, 12Research output: Contribution to journal › Article › peer-review
Open Access2 Link opens in a new tab Scopus citations -
Description of the draft genome sequence of Streptococcus salivarius eK12, a derivative of the probiotic strain Streptococcus salivarius K12 with a modified plasmid
Pierro, F. D., Thacharodi, A., Kumaraswami, M., Bertuccioli, A., Tanda, M. L. & Zerbinati, N., Aug 2025, In: Microbiology Resource Announcements. 14, 8Research output: Contribution to journal › Article › peer-review
Open Access2 Link opens in a new tab Scopus citations -
Environmental pH controls antimicrobial production by human probiotic Streptococcus salivarius
Nguyen, D. L., Saha, S., Thacharodi, A., Singh, B. B., Mitra, S., Do, H. & Kumaraswami, M., Jun 2025, In: Journal of bacteriology. 207, 6Research output: Contribution to journal › Article › peer-review
Open Access1 Link opens in a new tab Scopus citations -
Engineered probiotic overcomes pathogen defences using signal interference and antibiotic production to treat infection in mice
Do, H., Li, Z. R., Tripathi, P. K., Mitra, S., Guerra, S., Dash, A., Weerasekera, D., Makthal, N., Shams, S., Aggarwal, S., Singh, B. B., Gu, D., Du, Y., Olsen, R. J., LaRock, C., Zhang, W. & Kumaraswami, M., Feb 2024, In: Nature Microbiology. 9, 2, p. 502-513 12 p., 9.Research output: Contribution to journal › Article › peer-review
Open Access49 Link opens in a new tab Scopus citations
Prizes
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Presidential Award - Peer Reviewed Publication
Kumaraswami, M. (Recipient), 2025
Prize: Prize (including medals and awards)