Monisha Singh, MD

Projects

Projects per year 2011 2013 2014 2046

• 22 Active
• 36 Not started

Projects per year

Search results

• Active

  A PHASE 1, OPEN-LABEL, MULTICENTER STUDY OF JANX007 IN SUBJECTS WITH METASTATIC CASTRATION-RESISTANT PROSTATE CANCER

  Heyne, K. (Key Personnel), Miles, B. J. (Key Personnel), Satkunasivam, R. (Key Personnel), Singh, M. (Key Personnel) & Zhang, J. (Key Personnel)

  10/17/24 → …

  Project: Clinical Trial

• REVIVE: Replens Versus Intra-Vaginal Estrogen for the Treatment of Vaginal Dryness on Aromatase Inhibitor Therapy

  Niravath, P. A. (PI), Antosh, D. (Key Personnel), Chang, J. C. (Key Personnel), High, R. A. (Key Personnel), Hoopes, S. (Key Personnel), Mai, H. P. (Key Personnel), Singh, M. (Key Personnel), Sun, K. (Key Personnel) & Zaid, T. (Key Personnel)

  5/17/24 → …

  Project: Clinical Trial

• Atezolizumab and Bevacizumab Pre-Liver Transplantation for Patients with Hepatocellular Carcinoma Beyond Milan Criteria: A Feasibility Study

  Abdelrahim, M. (PI), Connor, A. A. (Key Personnel), Ghobrial, R. M. (Key Personnel), Gibbs, J. M. (Key Personnel), Graviss, E. A. (Key Personnel), Gupta, N. (Key Personnel), Kodali, S. (Key Personnel), Mobley, C. M. (Key Personnel), Moore, L. W. (Key Personnel), Rizk, E. (Key Personnel), Saharia, A. (Key Personnel), Singh, M. (Key Personnel) & Victor, III, D. W. (Key Personnel)

  1/18/23 → …

  Project: Clinical Trial

• An Open-Label Randomized Active-Controlled Phase II Clinical Study to Assess the Efficacy and Safety of Afuresertib Plus Paclitaxel Versus Paclitaxel in Patients with Platinum-ResistantOvarian Cancer

  Kamat, A. A. (PI), Alaniz, A. (CoI), Darcourt, J. (CoI), Singh, M. (CoI), Suri, A. (CoI) & Zaid, T. (CoI)

  3/15/21 → 3/14/46

  Project: Non Profit

• Sample and Data Collection for Houston Methodist Cancer Center Research

  Chang, J. C. (PI), Bernicker, E. H. (Key Personnel), Darcourt, J. (Key Personnel), Heyne, K. (Key Personnel), Niravath, P. A. (Key Personnel) & Singh, M. (Key Personnel)

  4/9/20 → …

  Project: Clinical Trial

• CTSU - IRB SUBMISSIONA Phase III Trial To Evaluate The Efficacy Of The Addition Of Inotuzumab Ozogamicin (A Conjugated Anti-Cd22 Monoclonal Antibody) To Frontline Therapy In Young Adults (Ages 18-39 Years) With Newly Diagnosed Precursor B-Cell ALL.

  Abdelrahim, M. (CoI), Bernicker, E. H. (CoI), Chang, J. C. (CoI), Heyne, K. (CoI), Niravath, P. A. (CoI), Singh, M. (CoI) & Zhang, J. (CoI)

  3/6/20 → 3/5/45

  Project: Non Profit

• A Phase III Randomized, Placebo-Controlled Study of Pembrolizumab (MK-3475, NSC #776864)) in addition to Paclitaxel and Carboplatin for Measurable Stage III or IVA, Stage IVB or Recurrent Endometrial Cancer

  Kamat, A. A. (PI), Darcourt, J. (CoI), Singh, M. (CoI), Suri, A. (CoI) & Zaid, T. (CoI)

  3/1/19 → 2/28/25

  Project: Non Profit

• Circulating tumor DNA 5-hydroxymethylcytosine as a novel biomarker for cancers.

  Li, Z. (PI), Abdelrahim, M. (Key Personnel), Chang, J. C. (Key Personnel), Darcourt, J. (Key Personnel), Pingali, S. R. (Key Personnel), Sahay, S. (Key Personnel), Shah, S. (Key Personnel), Singh, M. (Key Personnel), Zhang, J. (Key Personnel), Zhou, S. (Key Personnel) & Zu, Y. (Key Personnel)

  1/10/19 → …

  Project: Clinical Trial

• TAILOR RT: A RANDOMIZED TRIAL OF REGIONAL RADIOTHERAPY IN BIOMARKER LOW RISK NODE POSITIVE AND T3N0 BREAST CANCER

  Teh, B. S. (PI), Chang, J. C. (CoI), Farach, A. M. (CoI), Haque, W. M. (CoI), Morgan, P. B. (CoI), Niravath, P. A. (CoI), Shadle, K. M. (CoI), Shkedy, C. (CoI) & Singh, M. (CoI)

  5/30/18 → 5/29/28

  Project: Non Profit

• A phase III, multicenter, randomized, study of atezolizumab/placebo administered in combination with paclitaxel, carboplatin, and bevacizumab to patients with newly-diagnosed stage III or stage IV ovarian, fallopian tube, or primary peritoneal cancer

  Kamat, A. A. (PI), Alaniz, A. (CoI), Bernicker, E. H. (CoI), Darcourt, J. (CoI), Heyne, K. (CoI), Singh, M. (CoI), Suri, A. (CoI) & Zaid, T. (CoI)

  3/13/18 → 3/12/43

  Project: Non Profit

• A RANDOMIZED PHASE III DOUBLE BLINDED PLACEBO CONTROLLED TRIAL OFASPIRIN AS ADJUVANT THERAPY FOR HER2 NEGATIVE BREAST CANCER: THE ABCTRIAL

  Arentz, C. (PI), Abdelrahim, M. (CoI), Bernicker, E. H. (CoI), Chang, J. C. (CoI), Heyne, K. (CoI), Niravath, P. A. (CoI), Singh, M. (CoI) & Zhang, J. (CoI)

  12/8/16 → 12/7/41

  Project: Non Profit

• EAY131 - Molecular Analysis for Therapy Choice (MATCH)

  Bernicker, E. H. (PI), Chang, J. C. (CoI), Darcourt, J. (CoI), Heyne, K. (CoI), Kamat, A. A. (CoI), Pingali, S. R. (CoI) & Singh, M. (CoI)

  9/20/16 → 9/20/41

  Project: Federal Funding Agencies

• Stem Cell: Biomarkers Including Putative Stem Cells Markers in Human Breast Cancers

  Chang, J. C. (PI), Heyne, K. (Key Personnel), Niravath, P. A. (Key Personnel), Singh, M. (Key Personnel) & Templeton, S. (Key Personnel)

  3/20/14 → …

  Project: Clinical Trial

• Metastatic Stem Cells-ROLE OF CANCER STEM CELLS IN BREAST CANCER RECURRENCE AND METASTASIS

  Chang, J. C. (PI), Niravath, P. A. (Key Personnel) & Singh, M. (Key Personnel)

  3/20/14 → …

  Project: Clinical Trial

• A Randomized Phase II Trial of Radiation Therapy and Cisplatin Alone or in Combination withIntravenous Triapine in Women with Newly Diagnosed Bulky Stage IB2, Stage II, IIIB, or IVACancer of the Uterine Cervix or Stage II-IVA Vaginal Cancer.

  Zaid, T. (PI), Butler, E. B. (CoI), Darcourt, J. (CoI), Farach, A. M. (CoI), Kamat, A. A. (CoI), Shkedy, C. (CoI), Singh, M. (CoI) & Suri, A. (CoI)

  3/1/14 → 2/28/39

  Project: Non Profit

• A Randomized, Phase II/III Study of Pegylated Liposomal Doxorubicin and CTEP-Supplied Atezolizumab (IND #134427) Versus Pegylated Liposomal Doxorubicin/Bevacizumab and CTEP-Supplied Atezolizumab Versus Pegylated Liposomal Doxorubicin/Bevacizumab in P

  Kamat, A. A. (PI), Darcourt, J. (CoI), Singh, M. (CoI), Suri, A. (CoI) & Zaid, T. (CoI)

  3/1/14 → 2/28/39

  Project: Non Profit

• Colorectal Cancer Metastatic dMMR Immuno-Therapy (COMMIT) Study:A Randomized Phase III Study of mFOLFOX6/Bevacizumab Combination Chemotherapy with orwithout Atezolizumab or Atezolizumab Monotherapy in the First-Line Treatment of Patients withDefici

  Abdelrahim, M. (PI), Bernicker, E. H. (CoI), Darcourt, J. (CoI), Heyne, K. (CoI) & Singh, M. (CoI)

  3/1/14 → 2/28/39

  Project: Non Profit

• PHASE III RANDOMIZED STUDY OF SORAFENIB PLUS DOXORUBICIN VERSUS SORAFENIB IN PATIENTS WITH ADVANCED HEPATOCELLULAR CARCINOMA (HCC)

  Bernicker, E. H. (Key Personnel), Darcourt, J. (Key Personnel) & Singh, M. (Key Personnel)

  University of Michigan

  8/13/13 → 8/12/38

  Project: Non Profit

• A Phase II/III Trial of Neoadjuvant FOLFOX w/ Selective Use of Combined Modality Chemoradiation versus Preoperative Combined Modality Chemoradiation for Locally Advanced Rectal Cancer Patients Undergoing Low Anterior Resection w/ Total Mesorectal Excisio

  Bernicker, E. H. (Project Director), Darcourt, J. (Project Director) & Singh, M. (Project Director)

  University of Michigan

  6/11/13 → 6/10/38

  Project: Non Profit

• CAN DIET AND PHYSICAL ACTIVITY MODULATE OVARIAN, FALLOPIAN TUBE AND PRIMARY PERITONEAL CANCER PROGRESSION-FREE SURVIVAL?

  Kamat, A. A. (PI), Kaplan, A. L. (CoI) & Singh, M. (CoI)

  Gynecologic Oncology Group

  5/14/13 → 5/13/38

  Project: Non Profit

• A Randomized Double-Blind Placebo-Controlled Biomarker Modulation Study of Vitamin D in premenopausal Women at High Risk for Breast Cancer, Phase IIB

  Chang, J. C. (CoI) & Singh, M. (CoI)

  University of Michigan

  6/29/12 → 3/22/37

  Project: Federal Funding Agencies

• GUP09-145(Bionomics);

  Preti, H. A. (CoI) & Singh, M. (CoI)

  Hoosier Oncology Group

  7/1/11 → 11/15/38

  Project: Non Profit

• Not started

  Clinical Phase Ib/II Trial of L-NMMA Plus Docetaxel in the Treatment of Refractory Locally Advanced or Metastatic Triple Negative Breast Cancer Patients

  Niravath, P. A. (PI), Beinart, G. (Key Personnel) & Singh, M. (Key Personnel)

  Project: Clinical Trial

• Beamion BCGC-1: A Phase Ib dose escalation and Phase II dose optimization, randomized, open-label, multicenter trial of oral zongertinib (BI 1810631) in combination with intravenous trastuzumab deruxtecan (T-DXd) or in combination with intravenous trastuzumab emtansine (T-DM1) for treatment of patients with advanced HER2+ metastatic breast cancer (mBC) and metastatic gastric, gastroesophageal junction, or esophageal adenocarcinoma (mGEAC)

  Niravath, P. A. (PI), Abdelrahim, M. (Key Personnel), Chang, J. C. (Key Personnel), Heyne, K. (Key Personnel), Mai, H. P. (Key Personnel), Singh, M. (Key Personnel) & Sun, K. (Key Personnel)

  Project: Clinical Trial

• A Pilot Study of Hydroxytyrosol, a Component of Olive Oil for Breast Cancer Prevention In Women At High Risk Of Breast Cancer

  Chang, J. C. (PI), Arentz, C. (Key Personnel), Niravath, P. A. (Key Personnel), Singh, M. (Key Personnel) & Templeton, S. (Key Personnel)

  Project: Clinical Trial

• Phase Ib Trial of L-NMMA in Combination With Pembrolizumab in Patients With Melanoma, Non-Small Cell Lung Cancer, Head and Neck Squamous Cell Carcinoma, Classical Hodgkin Lymphoma, Urothelial Carcinoma, or Microsatellite Instability-High/Mismatch Repair

  Zhang, J. (PI), Heyne, K. (Key Personnel) & Singh, M. (Key Personnel)

  Project: Clinical Trial

• Neoadjuvant Combination Therapy of Lenvima® plus Transcatheter Arterial Chemoembolization (TACE) for Transplant-Eligible Patients with Large Hepatocellular Carcinoma

  Abdelrahim, M. (PI), Connor, A. A. (Key Personnel), Ghobrial, R. M. (Key Personnel), Gibbs, J. M. (Key Personnel), Graviss, E. A. (Key Personnel), Gupta, N. (Key Personnel), Heyne, K. (Key Personnel), Kodali, S. (Key Personnel), Moore, L. W. (Key Personnel), Rizk, E. (Key Personnel), Saharia, A. (Key Personnel), Singh, M. (Key Personnel) & Victor, III, D. W. (Key Personnel)

  Project: Clinical Trial

• A Prospective Registry Study to Evaluate the Effect of the DCISionRT Test on Treatment Decisions in Patients With DCIS Following Breast Conserving Therapy

  Templeton, S. (PI), Arentz, C. (Key Personnel), Chang, J. C. (Key Personnel), Darcourt, J. (Key Personnel), Dubrovsky, E. (Key Personnel), Haque, W. M. (Key Personnel), Heyne, K. (Key Personnel), Morgan, P. B. (Key Personnel), Niravath, P. A. (Key Personnel) & Singh, M. (Key Personnel)

  Project: Clinical Trial

• A Study to Assess the Antitumor Activity and Safety of IMAB362 in Combination With Nab-Paclitaxel and Gemcitabine (Nab-P + GEM) as First Line Treatment in Subjects With Claudin 18.2 (CLDN18.2) Positive, Metastatic Pancreatic Adenocarcinoma

  Abdelrahim, M. (PI), Chang, J. C. (Key Personnel), Heyne, K. (Key Personnel), Niravath, P. A. (Key Personnel), Singh, M. (Key Personnel) & Zhang, J. (Key Personnel)

  Project: Clinical Trial

• Durvalumab vs Placebo Following Stereotactic Body Radiation Therapy in Early Stage Non-small Cell Lung Cancer Patients

  Zhang, J. (PI), Haque, W. M. (Key Personnel), Heyne, K. (Key Personnel), Shadle, K. M. (Key Personnel) & Singh, M. (Key Personnel)

  Project: Clinical Trial

• GOG-0281

  Kamat, A. A. (PI), Alaniz, A. (Key Personnel), Singh, M. (Key Personnel) & Suri, A. (Key Personnel)

  Project: Clinical Trial

• PALbociclib CoLlaborative Adjuvant Study: A Randomized Phase III Trial of Palbociclib With Standard Adjuvant Endocrine Therapy Versus Standard Adjuvant Endocrine Therapy Alone for Hormone Receptor Positive (HR+) / Human Epidermal Growth Factor Receptor 2

  Niravath, P. A. (PI), Chang, J. C. (Key Personnel), Heyne, K. (Key Personnel) & Singh, M. (Key Personnel)

  Project: Clinical Trial

• GOG 213

  Kamat, A. A. (PI), Alaniz, A. (Key Personnel), Beinart, G. (Key Personnel), Coffey, D. (Key Personnel), Singh, M. (Key Personnel), Suri, A. (Key Personnel) & Zaid, T. (Key Personnel)

  Project: Clinical Trial

• Study of Sasanlimab (PF-06801591) in Combination With Bacillus Calmette-Guerin (BCG) in Participants With High-Risk Non-Muscle Invasive Bladder Cancer (CREST)

  Satkunasivam, R. (PI), Singh, M. (Key Personnel) & Zhang, J. (Key Personnel)

  Project: Clinical Trial

• A Phase 3, Randomized, Open-label Study to Evaluate Perioperative Enfortumab Vedotin Plus Pembrolizumab (MK-3475) Versus Neoadjuvant Gemcitabine and Cisplatin in Cisplatin-eligible Participants With Muscle-invasive Bladder Cancer (KEYNOTE-B15 / EV-304)

  Satkunasivam, R. (PI), Singh, M. (Key Personnel) & Zhang, J. (Key Personnel)

  Project: Clinical Trial

• GOG-0225

  Kamat, A. A. (PI), Alaniz, A. (Key Personnel), Singh, M. (Key Personnel) & Suri, A. (Key Personnel)

  Project: Clinical Trial

• A Randomized, Double-blind, Phase 3 Comparison of Platinum-based Therapy With TSR-042 and Niraparib Versus Standard of Care Platinum-based Therapy as First-line Treatment of Stage III or IV Nonmucinous Epithelial Ovarian Cancer (ENGOT-0V44 The FIRST)

  Suri, A. (PI), Alaniz, A. (Key Personnel), Singh, M. (Key Personnel) & Zaid, T. (Key Personnel)

  Project: Clinical Trial

• MK-7684A With or Without Other Anticancer Therapies in Participants With Selected Solid Tumors (MK-7684A-005) (KEYVIBE-005)

  Zaid, T. (PI), Alaniz, A. (Key Personnel), Beinart, G. (Key Personnel), Coffey, D. (Key Personnel), Ramirez, P. T. (Key Personnel), Singh, M. (Key Personnel) & Suri, A. (Key Personnel)

  Project: Clinical Trial

• GOG-0258

  Kamat, A. A. (PI), Beinart, G. (Key Personnel), Butler, E. B. (Key Personnel), Singh, M. (Key Personnel) & Suri, A. (Key Personnel)

  Project: Clinical Trial

• GOG0286B

  Kamat, A. A. (PI), Alaniz, A. (Key Personnel), Singh, M. (Key Personnel), Suri, A. (Key Personnel) & Zaid, T. (Key Personnel)

  Project: Clinical Trial

• Phase I Trial of Atezolizumab and Interleukin-12 Gene Therapy in Metastatic Non-Small Cell Lung Cancer With Progression on First-Line Immunotherapy With or Without Chemotherapy

  Zhang, J. (PI), Chan, E. Y. (Key Personnel), Gibbs, J. M. (Key Personnel), Heyne, K. (Key Personnel), Kim, M. P. (Key Personnel), Rudkovskaia, A. A. (Key Personnel) & Singh, M. (Key Personnel)

  Project: Clinical Trial

• Phase III Trial of Docetaxel vs. Docetaxel and Radium-223 for Metastatic Castration-Resistant Prostate Cancer (mCRPC)

  Heyne, K. (Key Personnel), Singh, M. (Key Personnel) & Zhang, J. (Key Personnel)

  Project: Clinical Trial

• Phase III Randomized Study of Concurrent Chemotherapy and Pelvic Radiation Therapy With or Without Adjuvant Chemotherapy in High-Risk Patients With Early-Stage Cervical Carcinoma Following Radical Hysterectomy (RTOG 0724/GOG-0724 )

  Kamat, A. A. (PI), Butler, E. B. (Key Personnel), Farach, A. M. (Key Personnel), Morgan, P. B. (Key Personnel), Singh, M. (Key Personnel) & Suri, A. (Key Personnel)

  Project: Clinical Trial

• A Randomized Phase III Trial of Radiation Therapy and Cisplatin Alone or in Combination With Intravenous Triapine in Women With Newly Diagnosed Bulky Stage IB2, Stage II, IIIB, or IVA Cancer of the Uterine Cervix or Stage II-IVA Vaginal Cancer (NRG-GY006)

  Zaid, T. (PI), Alaniz, A. (Key Personnel), Butler, E. B. (Key Personnel), Farach, A. M. (Key Personnel), Haque, W. M. (Key Personnel), Kamat, A. A. (Key Personnel), Morgan, P. B. (Key Personnel), Shadle, K. M. (Key Personnel), Shkedy, C. (Key Personnel), Singh, M. (Key Personnel) & Suri, A. (Key Personnel)

  Project: Clinical Trial

• Pivotal, Randomized, Open-label Study of Tumor Treating Fields (TTFields, 150kHz) Concomitant With Gemcitabine and Nab-paclitaxel for Front-line Treatment of Locally-advanced Pancreatic Adenocarcinoma

  Abdelrahim, M. (PI), Chang, J. C. (Key Personnel), Heyne, K. (Key Personnel), Niravath, P. A. (Key Personnel), Singh, M. (Key Personnel) & Templeton, S. (Key Personnel)

  Project: Clinical Trial

• A Phase II Trial of Ribociclib (LEE011) Plus Letrozole in Women With Recurrent Low-Grade Serous Carcinoma of the Ovary, Fallopian Tube or Peritoneum (GOG-3026)

  Kamat, A. A. (PI), Alaniz, A. (Key Personnel), Singh, M. (Key Personnel), Suri, A. (Key Personnel) & Zaid, T. (Key Personnel)

  Project: Clinical Trial

• Randomized Study of Erlotinib vs Observation in Patients With Completely Resected Epidermal Growth Factor Receptor (EGFR) Mutant Non-small Cell Lung Cancer (NSCLC)

  Zhang, J. (PI), Chang, J. C. (Key Personnel), Heyne, K. (Key Personnel), Niravath, P. A. (Key Personnel) & Singh, M. (Key Personnel)

  Project: Clinical Trial

• Phase II Open Label, Study of IMMU-132 in Metastatic Urothelial Cancer After Failure of Platinum-Based Regimen or Anti-PD-1/ PD-L1 Based Immunotherapy

  Abdelrahim, M. (Key Personnel), Chang, J. C. (Key Personnel), Heyne, K. (Key Personnel), Niravath, P. A. (Key Personnel) & Singh, M. (Key Personnel)

  Project: Clinical Trial

• A Randomized, Double-blind, Phase III Study, Comparing NIS793 in Combination With Gemcitabine and Nab-paclitaxel Versus (vs.) Placebo Combined With Gemcitabine and Nab-paclitaxel for First Line Treatment of Metastatic Pancreatic Ductal Adenocarcinoma

  Abdelrahim, M. (PI) & Singh, M. (Key Personnel)

  Project: Clinical Trial

• (PENELOPE-B) GBG-78 - BIG 1-13 - NSABP-B-54-I A Study of Palbociclib in Addition to Standard Endocrine Treatment in Hormone Receptor Positive Her2 Normal Patients With Residual Disease After Neoadjuvant Chemotherapy and Surgery

  Chang, J. C. (PI), Niravath, P. A. (Key Personnel) & Singh, M. (Key Personnel)

  Project: Clinical Trial