Research interests

The Fang lab employ zebrafish and mouse models to studying the role of lipid metabolism in angiogenesis and lymphangiogenesis. During his postdoctoral studies at UC San Diego, Dr. Fang discovered that apolipoprotein (apoA-I) binding protein (AIBP) controls angiogenesis via regulation of cholesterol homeostasis.Based upon the findings, the Fang laboratory will be focusing on the role of AIBP-regulated lipid metabolism in angiogenesis and lymphangiogenesis. We will use a plethora of disease models such as heart hypertrophy, heart ischemia and reperfusion, peripheral artery ischemia and reperfusion, corneal angiogenesis, and tumorigenesis in mice as well as in zebrafish heart regeneration. Both zebrafish and mouse model will be used to study the role of AIBP in lymphangiogenesis.

Keywords

    Free-text keywords

  • Angiogenesis, Lymphangiogenesis, hematopoiesis, cholesterol metabolism

    Research Area Keywords

  • Heart & Vascular

Fingerprint

Zebrafish
Concept: Zebrafish
Weight: 100%
Domain: Medicine & Life Sciences
Cholesterol
Concept: Cholesterol
Weight: 69%
Domain: Medicine & Life Sciences
Carrier Proteins
Concept: Carrier Proteins
Weight: 52%
Domain: Medicine & Life Sciences
Atherosclerosis
Concept: Atherosclerosis
Weight: 48%
Domain: Medicine & Life Sciences
Blood Vessels
Concept: Blood Vessels
Weight: 42%
Domain: Medicine & Life Sciences
Apolipoprotein A-I
Concept: Apolipoprotein A-I
Weight: 40%
Domain: Medicine & Life Sciences
Lipids
Concept: Lipids
Weight: 36%
Domain: Medicine & Life Sciences
Cell Polarity
Concept: Cell Polarity
Weight: 32%
Domain: Medicine & Life Sciences
Lipoproteins
Concept: Lipoproteins
Weight: 32%
Domain: Medicine & Life Sciences
Nutrition
Concept: Nutrition
Weight: 29%
Domain: Chemical Compounds
Research OutputsResearch Output authored by Longhou Fang is tagged with the concept

Journals

Circulation research

ISSNs: 0009-7330

Additional searchable ISSN (Electronic): 1524-4571

Lippincott Williams and Wilkins

Journal

3

Circulation

ISSNs: 0009-7322, 1524-4539

Lippincott Williams and Wilkins

Journal

2

Cell Research

ISSNs: 1001-0602

Additional searchable ISSN (Electronic): 1748-7838

Nature Publishing Group

Journal

2

Free Radical Biology and Medicine

ISSNs: 0891-5849

Additional searchable ISSN (Electronic): 1873-4596

Elsevier

Journal

1

Methodist DeBakey Cardiovascular Journal

ISSNs: 1947-6094

Additional searchable ISSN (Electronic): 1947-6108

Methodist DeBakey Heart & Vascular Center, United States

Journal

1
has published Research OutputsResearch Output by Longhou Fang

Research Network

Visualization: Institutional Network

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Longhou Fang

Visualization: Co-author Network

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Longhou Fang

Shared Pub. Internal Organizations

Houston Methodist Hospital

Organizational unit: Schools & Hospitals

3
2

Department of Cardiology

Organizational unit: Departments

1

Center for Bioenergetics

Organizational unit: Programs

1
has Research OutputsResearch Output by Longhou Fang

Shared Pub. External Organizations

University of California, San Diego

External organization: Unknown

18

Graduate University of Chinese Academy of Sciences

External organization: Unknown

3

Chinese Academy of Sciences

External organization: Academic

3

University Administration Building, Chinese University of Hong Kong, 1/F

External organization: Unknown

2

University of California at San Diego

External organization: Academic

2
has Research OutputsResearch Output by Longhou Fang

Shared Pub. Internal co-authors

has co-authored Research OutputsResearch Output with Longhou Fang

Shared Pub. External co-authors

Yury I. Miller

External person

19

Soo Ho Choi

External person

8

Zhengjun Chen

External person

5

Jennifer Pattison

External person

5

Felicidad Almazan

External person

4
has co-authored Research OutputsResearch Output with Longhou Fang

ID: 12616809