Personal profile
Personal profile
Kumar Pichumani, PhD, is a research scientist at the Neurosurgery Research Laboratory and Associate Research Member at Houston Methodist Research Institute. Dr. Pichumani is an NMR physicist and has worked in NMR spectroscopy since 1990. He developed new methods using first principles of NMR spin relaxation to increase both resolution and sensitivity so that complex biomacromolecules of larger molecular mass can be studied by NMR Spectroscopy. These research publications were cited by two Nobel Laureates in NMR spectroscopy.
Research interests
Dr. Pichumani's most recent research involves investigating in-vivo cancer metabolism using non- radioactive 13C enriched nutrients as infusion substrates (glucose, acetate, fatty acids), studying the fate of these substrates via high-resolution 13C NMR spectroscopy of surgically resected tumor tissues extracts. In a recent article published in CELL, he demonstrated that acetate acts as an alternate energy source for cancer cells in human glioblastoma patients and mouse models. He studied in India, Sweden and the US, gaining a diverse background spanning physics, mathematics, electronics, physical chemistry, NMR, Cancer Metabolism and biophysics.
Education/Academic qualification
Postdoctoral Fellowship, Indiana University Bloomington
… → Jun 1 2000
Award Date: Jun 1 2000
Postdoctoral Fellowship, Stockholm University
… → Jan 1 1999
Award Date: Jan 1 1999
PhD, Cross Correlations of coupled spins in NMR, Indian Institute of Science Bangalore
… → Dec 1 1997
Award Date: Dec 1 1997
Physics, MSc, Madurai Kamaraj University
… → Apr 1 1990
Award Date: Mar 31 1990
Physics and Mathematics, BSc, Madurai Kamaraj University
… → Apr 1 1988
Award Date: Mar 31 1988
Research Area Keywords
- Neurosciences
- Cancer
Free-text keywords
- Cancer metabolism
- NMR spectroscopy
- Molecular imaging
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Collaborations and top research areas from the last five years
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Integrated Clinical Genetic Analysis Reveals Transcriptional Neurotransmitter Receptor Dysregulation in Meningiomas Causing Seizure
Khan, A. B., McDonald, M. F., English, C., Nouri, S. H., Katlowitz, K. A., Lau, S., Patel, R., Rojas, D., Harmanci, A., Jalali, A., Rao, G., Pichumani, K., Harmanci, A. S., Klisch, T. J. & Patel, A. J., Feb 12 2026, In: Neurosurgery.Research output: Contribution to journal › Article › peer-review
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Biochemical Characterization of Rhabdoid Meningioma by Proton Magnetic Resonance Spectroscopy
Ijare, O. B., Powell, S.Z.-E., Baskin, D. S. & Pichumani, K., Nov 11 2025, p. v443.Research output: Contribution to conference › Abstract › peer-review
Open Access -
Case Report: Metabolic alterations and cholesterol esterification in a low-grade diffuse astrocytoma patient who progressed to glioblastoma at recurrence
Ijare, O. B., Baskin, D. S., Powell, S. Z. & Pichumani, K., Sep 18 2025, In: Frontiers in Oncology. 15, 1651974.Research output: Contribution to journal › Article › peer-review
Open Access -
Case Report: Metabolic alterations and cholesterol esterification in a low-grade diffuse astrocytoma patient who progressed to glioblastoma at recurrence
Ijare, O. B., Baskin, D. S., Powell, S. Z. & Pichumani, K., Sep 19 2025, In: Frontiers in Oncology. 15, p. 1651974 1651974.Research output: Contribution to journal › Article › peer-review
Open Access -
Case Report: A new noninvasive device-based treatment of a mesencephalic H3 K27M glioma
Helekar, S. A., Ijare, O. B., Sharpe, M. A., Pichumani, K. & Baskin, D. S., 2025, In: Frontiers in Oncology. 15, 1626516.Research output: Contribution to journal › Article › peer-review
Open Access
Prizes
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Presidential Award - Career Cornerstone
Pichumani, K. (Recipient), 2023
Prize: Prize (including medals and awards)
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Presidential Award - NIH Competitiveness
Pichumani, K. (Recipient), 2020
Prize: Prize (including medals and awards)