Personal profile

Kumar Pichumani, PhD, is a research scientist at the Neurosurgery Research Laboratory and Associate Research Member at Houston Methodist Research Institute. Dr. Pichumani is an NMR physicist and has worked in NMR spectroscopy since 1990. He developed new methods using first principles of NMR spin relaxation to increase both resolution and sensitivity so that complex biomacromolecules of larger molecular mass can be studied by NMR Spectroscopy. These research publications were cited by two Nobel Laureates in NMR spectroscopy.

Research interests

Dr. Pichumani's most recent research involves investigating in-vivo cancer metabolism using non- radioactive 13C enriched nutrients as infusion substrates (glucose, acetate, fatty acids), studying the fate of these substrates via high-resolution 13C NMR spectroscopy of surgically resected tumor tissues extracts. In a recent article published in CELL, he demonstrated that acetate acts as an alternate energy source for cancer cells in human glioblastoma patients and mouse models. He studied in India, Sweden and the US, gaining a diverse background spanning physics, mathematics, electronics, physical chemistry, NMR, Cancer Metabolism and biophysics.

Keywords

    Free-text keywords

  • Cancer metabolism, NMR spectroscopy, Molecular imaging

    Research Area Keywords

  • Neurosciences
  • Cancer

Fingerprint

Brain Neoplasms
Concept: Brain Neoplasms
Weight: 100%
Domain: Medicine & Life Sciences
Acetates
Concept: Acetates
Weight: 98%
Domain: Medicine & Life Sciences
Glucose
Concept: Glucose
Weight: 82%
Domain: Medicine & Life Sciences
Chemical shift
Concept: Chemical shift
Weight: 80%
Domain: Chemical Compounds
Pituitary Neoplasms
Concept: Pituitary Neoplasms
Weight: 69%
Domain: Medicine & Life Sciences
chemical equilibrium
Concept: chemical equilibrium
Weight: 65%
Domain: Physics & Astronomy
Semantic group: Chemistry and Materials
Magnetic Resonance Spectroscopy
Concept: Magnetic Resonance Spectroscopy
Weight: 61%
Domain: Medicine & Life Sciences
Isotopes
Concept: Isotopes
Weight: 61%
Domain: Medicine & Life Sciences
Anisotropy
Concept: Anisotropy
Weight: 59%
Domain: Chemical Compounds
Tumors
Concept: Tumors
Weight: 59%
Domain: Chemical Compounds
Research OutputsResearch Output authored by Kumar Pichumani is tagged with the concept

Journals

Analytical Biochemistry

ISSNs: 0003-2697

Additional searchable ISSN (Electronic): 1096-0309

Academic Press

Journal

2

Scientific Reports

Additional searchable ISSN (Electronic): 2045-2322

The Author(s) SN -

Journal

2

Journal of Physical Chemistry B

ISSNs: 1520-6106, 1089-5647

American Chemical Society

Journal

2

Journal of Neurochemistry

ISSNs: 0022-3042

Wiley

Journal

1

Cancers

Additional searchable ISSN (Electronic): 2072-6694

Multidisciplinary Digital Publishing Institute (MDPI)

Journal

1
has published Research OutputsResearch Output by Kumar Pichumani

Research Network

Visualization: Institutional Network

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Kumar Pichumani

Visualization: Co-author Network

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Kumar Pichumani

Shared Pub. Internal Organizations

Neurosciences Research Program

Organizational unit: Programs

6

Houston Methodist Hospital

Organizational unit: Schools & Hospitals

5
has Research OutputsResearch Output by Kumar Pichumani

Shared Pub. External Organizations

University of Texas Southwestern Medical Center

External organization: Academic

5

Indiana University Bloomington

External organization: Academic

2

VA North Texas Care System

External organization: Unknown

2

UT Southwestern Medical Center

External organization: Unknown

2

University of Texas at Dallas

External organization: Academic

2
has Research OutputsResearch Output by Kumar Pichumani

Shared Pub. Internal co-authors

has co-authored Research OutputsResearch Output with Kumar Pichumani

Shared Pub. External co-authors

Robert Bachoo

External person

6

Craig Malloy

External person

6

Ralph J. DeBerardinis

External person

5

Elizabeth A. Maher

External person

5

Tomoyuki Mashimo

External person

4
has co-authored Research OutputsResearch Output with Kumar Pichumani

ID: 29603497