Research outputs

  1. 2019
  2. Erratum for Kirkpatrick et al., "Inducible Lung Epithelial Resistance Requires Multisource Reactive Oxygen Species Generation To Protect against Viral Infections"

    Kirkpatrick, C. T., Wang, Y., Leiva Juarez, M. M., Shivshankar, P., Pantaleón García, J., Plumer, A. K., Kulkarni, V. V., Ware, H. H., Gulraiz, F., Chavez Cavasos, M. A., Martinez Zayas, G., Wali, S., Rice, A. P., Liu, H., Tour, J. M., Sikkema, W. K. A., Cruz Solbes, A. S., Youker, K. A., Tuvim, M. J., Dickey, B. F. & 1 othersEvans, S. E., Apr 2 2019, In : mBio. 10, 2

    Research output: Contribution to journalComment/debate

  3. 2018
  4. Small molecule disruption of G protein βγ subunit signaling reprograms human macrophage phenotype and prevents autoimmune myocarditis in rats

    Karuppagounder, V., Bajpai, A., Meng, S., Arumugam, S., Sreedhar, R., Giridharan, V. V., Guha, A., Bhimaraj, A., Youker, K. A., Palaniyandi, S. S., Karmouty-Quintana, H., Kamal, F., Spiller, K. L., Watanabe, K. & Amirthalingam Thandavarayan, R., Jul 1 2018, In : PLoS ONE. 13, 7, e0200697.

    Research output: Contribution to journalArticle

  5. Efficacy of sustained delivery of GC-1 from a Nanofluidic system in a spontaneously obese non-human primate: a case study

    Filgueira, C. S., Bruno, G., Smith, Z. W., Chua, C. Y. X., Ballerini, A., Folci, M., Gilbert, A. L., Jain, P., Sastry, J. K., Nehete, P. N., Shelton, K. A., Hill, L. R., Ali, A., Youker, K. A. & Grattoni, A., Jun 1 2018, In : Biomedical Microdevices. 20, 2, 49.

    Research output: Contribution to journalArticle

  6. Inducible lung epithelial resistance requires multisource reactive oxygen species generation to protect against viral infections

    Kirkpatrick, C. T., Wang, Y., Leiva Juarez, M. M., Shivshankar, P., Pantaleón García, J., Plumer, A. K., Kulkarni, V. V., Ware, H. H., Gulraiz, F., Chavez Cavasos, M. A., Martinez Zayes, G., Wali, S., Rice, A. P., Liu, H., Tour, J. M., Sikkema, W. K. A., Cruz Solbes, A. S., Youker, K. A., Tuvim, M. J., Dickey, B. F. & 1 othersEvans, S. E., May 1 2018, In : mBio. 9, 3, e00696-18.

    Research output: Contribution to journalArticle

  7. 2017
  8. Functionally redundant control of cardiac hypertrophic signaling by inositol 1,4,5-trisphosphate receptors

    Garcia, M. I., Karlstaedt, A., Chen, J. J., Amione-Guerra, J., Youker, K. A., Taegtmeyer, H. & Boehning, D., Nov 1 2017, In : Journal of Molecular and Cellular Cardiology. 112, p. 95-103 9 p.

    Research output: Contribution to journalArticle

  9. Inhibition of hyaluronan synthesis attenuates pulmonary hypertension associated with lung fibrosis

    Collum, S. D., Chen, N. Y., Hernandez, A. M., Hanmandlu, A., Sweeney, H., Mertens, T. C. J., Weng, T., Luo, F., Molina, J. G., Davies, J., Horan, I. P., Morrell, N. W., Amione-Guerra, J., Al-Jabbari, O., Youker, K., Sun, W., Rajadas, J., Bollyky, P. L., Akkanti, B. H., Jyothula, S. & 3 othersSinha, N., Guha, A. & Karmouty-Quintana, H., Oct 1 2017, In : British Journal of Pharmacology. 174, 19, p. 3284-3301 18 p.

    Research output: Contribution to journalArticle

  10. Rapamycin nanoparticles localize in diseased lung vasculature and prevent pulmonary arterial hypertension

    Segura-Ibarra, V., Amione-Guerra, J., Cruz-Solbes, A. S., Cara, F. E., Iruegas-Nunez, D. A., Wu, S., Youker, K. A., Bhimaraj, A., Torre-Amione, G., Ferrari, M., Karmouty-Quintana, H., Guha, A. & Blanco, E., May 30 2017, In : International Journal of Pharmaceutics. 524, 1-2, p. 257-267 11 p.

    Research output: Contribution to journalArticle

  11. AIBP Limits Angiogenesis Thorough γ-Secretase-Mediated Upregulation of Notch Signaling

    Mao, R., Meng, S., Gu, Q., Araujo-Gutierrez, R., Kumar, S., Yan, Q., Almazan, F., Youker, K. A., Fu, Y., Pownall, H. J., Cooke, J. P., Miller, Y. I. & Fang, L., Mar 23 2017, (Accepted/In press) In : Circulation research.

    Research output: Contribution to journalArticle

  12. Epithelial to mesenchymal transition (EMT) and endothelial to mesenchymal transition (EndMT): Role and implications in kidney fibrosis

    Cruz-Solbes, A. S. & Youker, K. A., 2017, Kidney Development and Disease. Miller, R. K. (ed.). Springer Verlag, Vol. 60. p. 345-372 28 p. (Results and Problems in Cell Differentiation; vol. 60).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  13. Pulmonary Hypertension Associated with Idiopathic Pulmonary Fibrosis: Current and Future Perspectives

    Collum, S. D., Amione-Guerra, J., Cruz-Solbes, A. S., Difrancesco, A., Hernandez, A. M., Hanmandlu, A., Youker, K., Guha, A. & Karmouty-Quintana, H., 2017, In : Canadian Respiratory Journal. 2017, 1430350.

    Research output: Contribution to journalReview article

  14. 2016
  15. MicroRNA-126 overexpression rescues diabetes-induced impairment in efferocytosis of apoptotic cardiomyocytes

    Suresh Babu, S., Amirthalingam Thandavarayan, R., Joladarashi, D., Jeyabal, P., Krishnamurthy, S., Bhimaraj, A., Youker, K. A. & Krishnamurthy, P., Nov 9 2016, In : Scientific Reports. 6, 36207.

    Research output: Contribution to journalArticle

  16. Macrophage bone morphogenic protein receptor 2 depletion in idiopathic pulmonary fibrosis and Group III pulmonary hypertension

    Chen, N. Y., Collum, S. D., Luo, F., Weng, T., Le, T. T., Hernandez, A. M., Philip, K., Molina, J. G., Garcia-Morales, L. J., Cao, Y., Ko, T. C., Amione-Guerra, J., Al-Jabbari, O., Bunge, R. R., Youker, K. A., Bruckner, B. A., Hamid, R., Davies, J., Sinha, N. & Karmouty-Quintana, H., Aug 1 2016, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 311, 2, p. 238-254 17 p.

    Research output: Contribution to journalArticle

  17. MicroRNA-9 inhibits hyperglycemia-induced pyroptosis in human ventricular cardiomyocytes by targeting ELAVL1

    Jeyabal, P., Amirthalingam Thandavarayan, R., Joladarashi, D., Suresh Babu, S., Krishnamurthy, S., Bhimaraj, A., Youker, K. A., Kishore, R. & Krishnamurthy, P., Mar 18 2016, In : Biochemical and Biophysical Research Communications. 471, 4, p. 423-429 7 p.

    Research output: Contribution to journalArticle

  18. Combination of angiotensin II and l-NG-nitroarginine methyl ester exacerbates mitochondrial dysfunction and oxidative stress to cause heart failure

    Hamilton, D. J., Zhang, A., Li, S., Cao, T. N., Smith, J. A., Vedula, I., Cordero-Reyes, A. M., Youker, K. A., Torre-Amione, G. & Gupte, A. A., Mar 15 2016, In : American Journal of Physiology - Heart and Circulatory Physiology. 310, 6, p. H667-H680 14 p.

    Research output: Contribution to journalArticle

  19. Rnd3/RhoE Modulates Hypoxia-Inducible Factor 1α/Vascular Endothelial Growth Factor Signaling by Stabilizing Hypoxia-Inducible Factor 1α and Regulates Responsive Cardiac Angiogenesis

    Yue, X., Lin, X., Yang, T., Yang, X., Yi, X., Jiang, X., Li, X., Li, T., Guo, J., Dai, Y., Shi, J., Wei, L., Youker, K. A., Torre, G., Yu, Y., Andrade, K. C. & Chang, J., Mar 1 2016, In : Hypertension. 67, 3, p. 597-605 9 p.

    Research output: Contribution to journalArticle

  20. A specifically designed nanoconstruct associates, internalizes, traffics in cardiovascular cells, and accumulates in failing myocardium: A new strategy for heart failure diagnostics and therapeutics

    Ruiz-Esparza, G. U., Segura-Ibarra, V., Cordero-Reyes, A. M., Youker, K. A., Serda, R. E., Cruz-Solbes, A. S., Amione-Guerra, J., Yokoi, K., Kirui, D. K., Cara, F. E., Paez-Mayorga, J., Flores-Arredondo, J. H., Guerrero-Beltrán, C. E., Garcia-Rivas, G., Ferrari, M., Blanco, E. & Torre-Amione, G., Feb 1 2016, In : European Journal of Heart Failure. 18, 2, p. 169-178 10 p.

    Research output: Contribution to journalArticle

  21. Full expression of cardiomyopathy is partly dependent on B-cells: A pathway that involves cytokine activation, immunoglobulin deposition, and activation of apoptosis

    Cordero-Reyes, A. M., Youker, K. A., Trevino, A. R., Celis, R., Hamilton, D. J., Flores-Arredondo, J. H., Orrego, C. M., Bhimaraj, A., Estep, J. D. & Torre-Amione, G., 2016, In : Journal of the American Heart Association. 5, 1, p. 1-12 12 p.

    Research output: Contribution to journalArticle

  22. 2015
  23. Enhanced Cardiac Regenerative Ability of Stem Cells After Ischemia-Reperfusion Injury: Role of Human CD34(+) Cells Deficient in MicroRNA-377

    Joladarashi, D., Srikanth Garikipati, V. N., Thandavarayan, R. A., Verma, S. K., Mackie, A. R., Khan, M., Gumpert, A. M., Bhimaraj, A., Youker, K. A., Uribe, C., Suresh Babu, S., Jeyabal, P., Kishore, R. & Krishnamurthy, P., Nov 17 2015, In : Journal of the American College of Cardiology. 66, 20, p. 2214-2226 13 p.

    Research output: Contribution to journalArticle

  24. Standardized extracts from black bean coats (Phaseolus vulgaris L.) prevent adverse cardiac remodeling in a murine model of non-ischemic cardiomyopathy

    García-Rivas, G., Youker, K. A., Orrego, C., Flores-Arredondo, J., Guerrero-Beltrán, C. E., Cordero-Reyes, A., Gutiérrez-Uribe, J. A., García, M., Serna-Saldivar, S. O. & Torre, G., Oct 12 2015, In : RSC Advances. 5, 110, p. 90858-90865 8 p.

    Research output: Contribution to journalArticle

  25. Differential mitochondrial function in remodeled right and non-remodeled left ventricles in pulmonary hypertension.

    Gupte, A. A., Cordero-Reyes, A. M., Youker, K., Matsunami, R. K., Engler, D. A., Loebe, M., Ashrith, G., Torre, G. & Hamilton, D. J., Sep 2015, In : Journal of Cardiac Failure. p. Epub

    Research output: Contribution to journalArticle

  26. 2014
  27. High proportion of patients with end-stage heart failure regardless of aetiology demonstrates anti-cardiac antibody deposition in failing myocardium: Humoral activation, a potential contributor of disease progression

    Youker, K. A., Assad-Kottner, C., Cordero-Reyes, A. M., Trevino, A. R., Flores-Arredondo, J. H., Barrios, R., Fernandez-Sada, E., Estep, J. D., Bhimaraj, A. & Torre, G., Apr 21 2014, In : European Heart Journal. 35, 16, p. 1061-1068 8 p.

    Research output: Contribution to journalArticle

  28. Freshly isolated mitochondria from failing human hearts exhibit preserved respiratory function

    Cordero-Reyes, A. M., Gupte, A. A., Youker, K. A., Loebe, M., Hsueh, W. A., Torre, G., Taegtmeyer, H. & Hamilton, D. J., Mar 1 2014, In : Journal of Molecular and Cellular Cardiology. 68, p. 98-105 8 p.

    Research output: Contribution to journalArticle

  29. Mechanical unloading promotes myocardial energy recovery in human heart failure

    Gupte, A. A., Hamilton, D. J., Cordero-Reyes, A. M., Youker, K. A., Yin, Z., Estep, J. D., Stevens, R. D., Wenner, B., Ilkayeva, O., Loebe, M., Peterson, L. E., Lyon, C. J., Wong, S. T., Newgard, C. B., Torre, G., Taegtmeyer, H. & Hsueh, W. A., Jan 1 2014, In : Circulation: Cardiovascular Genetics. 7, 3, p. 266-276 11 p.

    Research output: Contribution to journalArticle

  30. Molecular and cellular correlates of cardiac function in end-stage DCM: A study using speckle tracking echocardiography

    Cordero-Reyes, A. M., Youker, K. A., Estep, J. D., Torre, G. & Nagueh, S., Jan 1 2014, In : JACC: Cardiovascular Imaging. 7, 5, p. 441-452 12 p.

    Research output: Contribution to journalArticle

  31. 2013
  32. The role of B-cells in heart failure.

    Cordero-Reyes, A. M., Youker, K. A. & Torre, G., Jan 1 2013, In : Methodist DeBakey Cardiovascular Journal. 9, 1, p. 15-19 5 p.

    Research output: Contribution to journalArticle

  33. 2012
  34. Molecular, cellular, and functional characterization of myocardial regions in hypertrophic cardiomyopathy

    Cordero-Reyes, A. M., Youker, K. A., Hamilton, D. J., Torre, G., Marian, A. J. & Nagueh, S., May 1 2012, In : Circulation: Cardiovascular Imaging. 5, 3, p. 419-422 4 p.

    Research output: Contribution to journalArticle

  35. 2011
  36. Erratum: Neovascularization and remodeling in patients injected with autologous bone marrow cells (ASAIO Journal 57:2 (103))

    Bruckner, B. A., Garcia-Morales, L. J., Youker, K. A., Motomura, T., Bunge, R. R., Ramlawi, B., Estep, J. & Loebe, M., Jul 1 2011, In : ASAIO Journal. 57, 4

    Research output: Contribution to journalArticle

  37. Cellular Evidence of Reverse Cardiac Remodeling Induced by Cardiac Resynchronization Therapy

    Orrego, C. M., Nasir, N., Oliveira, G. H., Flores-Arredondo, J. H., Cordero-Reyes, A. M., Loebe, M., Youker, K. A. & Torre-Amione, G., May 1 2011, In : Congestive Heart Failure. 17, 3, p. 140-146 7 p.

    Research output: Contribution to journalArticle

  38. 2010
  39. Therapeutic plasma exchange a potential strategy for patients with advanced heart failure

    Torre, G., Orrego, C. M., Khalil, N., Kottner-Assad, C., Leveque, C., Celis, R., Youker, K. A. & Estep, J. D., Dec 20 2010, In : Journal of Clinical Apheresis. 25, 6, p. 323-330 8 p.

    Research output: Contribution to journalArticle

  40. Reversal of secondary pulmonary hypertension by axial and pulsatile mechanical circulatory support

    Torre, G., Southard, R. E., Loebe, M. M., Youker, K. A., Bruckner, B. A., Estep, J. D., Tierney, M. & Noon, G. P., Feb 1 2010, In : Journal of Heart and Lung Transplantation. 29, 2, p. 195-200 6 p.

    Research output: Contribution to journalArticle

  41. 2009
  42. Heart failure research: translating basic science into therapies.

    Youker, K. A. & Torre, G., Dec 1 2009, In : Methodist DeBakey Cardiovascular Journal. 5, 3, p. 38-41 4 p.

    Research output: Contribution to journalArticle

  43. Mast cell burden and reticulin fibrosis in the myeloproliferative neoplasms: A computer-assisted image analysis study

    Ahmed, A., Powers, M. P., Youker, K. A., Rice, L., Ewton, A. A., Dunphy, C. H. & Chang, C. C., Sep 15 2009, In : Pathology Research and Practice. 205, 9, p. 634-638 5 p.

    Research output: Contribution to journalArticle

  44. Reciprocal regulation of myocardial microRNAs and messenger RNA in human cardiomyopathy and reversal of the microRNA signature by biomechanical support

    Matkovich, S. J., Van Booven, D. J., Youker, K. A., Torre, G., Diwan, A., Eschenbacher, W. H., Dorn, L. E., Watson, M. A., Margulies, K. B. & Dorn, G. W., Mar 10 2009, In : Circulation. 119, 9, p. 1263-1271 9 p.

    Research output: Contribution to journalArticle

  45. 2008
  46. The Use of Continuous Milrinone Therapy as Bridge to Transplant Is Safe in Patients With Short Waiting Times

    Assad-Kottner, C., Chen, D., Jahanyar, J., Cordova, F., Summers, N., Loebe, M., Merla, R., Youker, K. A. & Torre, G., Dec 1 2008, In : Journal of Cardiac Failure. 14, 10, p. 839-843 5 p.

    Research output: Contribution to journalArticle

  47. Increased Expression of Stem Cell Factor and Its Receptor After Left Ventricular Assist Device Support: A Potential Novel Target for Therapeutic Interventions in Heart Failure

    Jahanyar, J., Youker, K. A., Torre, G., Koerner, M. M., Bruckner, B. A., Noon, G. P. & Loebe, M., Jul 1 2008, In : Journal of Heart and Lung Transplantation. 27, 7, p. 701-709 9 p.

    Research output: Contribution to journalArticle

  48. The role of mast cells after solid organ transplantation

    Jahanyar, J., Koerner, M. M., Loebe, M., Youker, K. A., Torre, G. & Noon, G. P., May 27 2008, In : Transplantation. 85, 10, p. 1365-1371 7 p.

    Research output: Contribution to journalArticle

  49. 2007
  50. Rad GTPase deficiency leads to cardiac hypertrophy

    Chang, L., Zhang, J., Tseng, Y. H., Xie, C. Q., Ilany, J., Brüning, J. C., Sun, Z., Zhu, X., Cui, T., Youker, K. A., Yang, Q., Day, S. M., Kahn, C. R. & Chen, Y. E., Dec 1 2007, In : Circulation. 116, 25, p. 2976-2983 8 p.

    Research output: Contribution to journalArticle

  51. Mast Cell-Derived Cathepsin g: A Possible Role in The Adverse Remodeling of The Failing Human Heart

    Jahanyar, J., Youker, K. A., Loebe, M., Assad-Kottner, C., Koerner, M. M., Torre, G. & Noon, G. P., May 15 2007, In : Journal of Surgical Research. 140, 2, p. 199-203 5 p.

    Research output: Contribution to journalArticle

  52. Lack of NF-κB1 (p105/p50) attenuates unloading-induced downregulation of PPARα and PPARα-regulated gene expression in rodent heart

    Razeghi, P., Wang, M. E., Youker, K. A., Golfman, L., Stepkowski, S. & Taegtmeyer, H., Apr 1 2007, In : Cardiovascular Research. 74, 1, p. 133-139 7 p.

    Research output: Contribution to journalArticle

  53. Mechanical unloading of the heart activates the calpain system

    Razeghi, P., Volpini, K. C., Wang, M. E., Youker, K. A., Stepkowski, S. & Taegtmeyer, H., Feb 1 2007, In : Journal of Molecular and Cellular Cardiology. 42, 2, p. 449-452 4 p.

    Research output: Contribution to journalArticle

  54. Recurrent Device Thrombi During Mechanical Circulatory Support With an Axial-flow Pump Is a Treatable Condition and Does Not Preclude Successful Long-term Support

    Jahanyar, J., Noon, G. P., Koerner, M. M., Youker, K. A., Malaisrie, S. C., Ngo, U. Q., Torre, G. & Loebe, M., Feb 1 2007, In : Journal of Heart and Lung Transplantation. 26, 2, p. 200-203 4 p.

    Research output: Contribution to journalArticle

  55. Decorin-mediated Transforming Growth Factor-β Inhibition Ameliorates Adverse Cardiac Remodeling

    Jahanyar, J., Joyce, D. L., Southard, R. E., Loebe, M., Noon, G. P., Koerner, M. M., Torre, G. & Youker, K. A., Jan 1 2007, In : Journal of Heart and Lung Transplantation. 26, 1, p. 34-40 7 p.

    Research output: Contribution to journalArticle

  56. 2006
  57. Myocardial contrast echocardiography of radiofrequency ablation lesions

    Panescu, D., Rao, L., Ding, C., Sun, H., Youker, K. A., Nagueh, S. & Khoury, D. S., Dec 1 2006, Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. p. 6689-6692 4 p. 4030633

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  58. Free fatty acids inhibit insulin signaling-stimulated endothelial nitric oxide synthase activation through upregulating PTEN or inhibiting Akt kinase

    Xing, L. W., Zhang, L., Youker, K. A., Zhang, M. X., Wang, J., LeMaire, S. A., Coselli, J. S. & Shen, Y. H., Aug 1 2006, In : Diabetes. 55, 8, p. 2301-2310 10 p.

    Research output: Contribution to journalArticle

  59. 2005
  60. Quantitative changes in mast cell populations after left ventricular assist device implantation

    Akgul, A., Youker, K. A., Noon, G. P. & Loebe, M., May 1 2005, In : ASAIO Journal. 51, 3, p. 275-280 6 p.

    Research output: Contribution to journalArticle

  61. Fluorescence imaging microscopy of cellular markers in ischemic vs non-ischemic cardiomyopathy after left ventricular unloading

    Bick, R. J., Bagwell, S. H., Jones, C. E., Poindexter, B. J., Buja, L. M., Youker, K. A., Grigore, A., Clubb, F., Radovancevic, B. & Frazier, O. H., Apr 1 2005, In : Journal of Heart and Lung Transplantation. 24, 4, p. 454-461 8 p.

    Research output: Contribution to journalArticle

  62. Placement of a left ventricular assist device in a patient with dextrocardia

    Southard, R. E., Nelson, J. C., Joyce, D. L., Thompson, L. O., Skrabal, C. A., Torre, G., Youker, K. A., Noon, G. P. & Loebe, M., Mar 1 2005, In : Journal of Heart and Lung Transplantation. 24, 3, p. 338-339 2 p.

    Research output: Contribution to journalArticle

  63. Organ-specific regulation of pro-inflammatory molecules in heart, lung, and kidney following brain death

    Skrabal, C. A., Thompson, L. O., Potapov, E. V., Southard, R. E., Joyce, D. L., Youker, K. A., Noon, G. P. & Loebe, M., Jan 1 2005, In : Journal of Surgical Research. 123, 1, p. 118-125 8 p.

    Research output: Contribution to journalArticle

  64. Plasma neurohormone levels correlate with left ventricular functional and morphological improvement in LVAD patients

    Thompson, L. O., Skrabal, C. A., Loebe, M., Lafuente, J. A., Roberts, R. R., Akgul, A., Jones, V., Bruckner, B. A., Thohan, V., Noon, G. P. & Youker, K. A., Jan 1 2005, In : Journal of Surgical Research. 123, 1, p. 25-32 8 p.

    Research output: Contribution to journalArticle

  65. 2004
  66. Intramyocardial lipid accumulation in the failing human heart resembles the lipotoxic rat heart

    Sharma, S., Adrogue, J. V., Golfman, L., Uray, I., Lemm, J., Youker, K. A., Noon, G. P., Frazier, O. H. & Taegtmeyer, H., Nov 1 2004, In : FASEB Journal. 18, 14, p. 1692-1700 9 p.

    Research output: Contribution to journalArticle

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