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Keith A. Youker, PhD

  • 7256 Citations
  • 41 h-Index
1989 …2020

Research output per year

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Personal profile

Personal profile

Dr. Keith Youker earned his Ph.D. in Cardiovascular Sciences from Baylor College of Medicine and was the first graduate from this program. The program initially used a broad knowledge approach to training including course work from medical school, graduate school, and cardiovascular core courses designed for basic scientists to work in clinical cardiovascular research. His dissertation work earned him a nomination for the Sigma Xi “Excellence in Science Dissertation Award”. Since graduation, Dr. Youker has been a faculty member in both the departments of Medicine and Surgery at Baylor College of Medicine prior to joining Houston Methodist Hospital. He has served as an ad hoc reviewer for the journals of Circulation, American Journal of Pathology, ASAIO and the Journal of Heart and Lung Transplantation. Dr. Youker’s primary focus has been in heart failure with a particular interest in inflammation and its role in the progression of heart failure. Dr. Youker prefers a hands-on approach in the laboratory and is expert in many areas from electron microscopy to molecular biology techniques and has earned a reputation of excellence in cardiovascular immunopathology research.

Research interests

Dr. Youker focuses on research of the immune system in heart failure and metabolism in heart failure.

Education/Academic qualification

Cardiovascular Sciences, PhD, Baylor College of Medicine

Free-text keywords

  • Immunology
  • Cardiac
  • Transplantation
  • LVAD
  • Heart Failure

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Projects

Reversal of Heart Failure: Role of Vascular Recovery

Chen, K., Cooke, J. P., Meng, S. & Youker, K. A.

7/15/20 → 3/31/24

Project: Federal Funding Agencies

Association of LVAD inflow cannula position with the development of acquired VWD and altered angiogenesis

Kassi, M., Bhimaraj, A., Graviss, E. A., Guha, A., Kim, J. H., Trachtenberg, B. H. & Youker, K. A.

10/30/19 → …

Project: Clinical Trial

Research Output

Erratum: Inducible lung epithelial resistance requires multisource reactive oxygen species generation to protect against viral infections (mBio, (2018) 9(3), e00696-18, 10.1128/mBio.00696-18)

Kirkpatrick, C. T., Wang, Y., Leiva Juarez, M. M., Shivshankar, P., Pantaleón García, J., Plumer, A. K., Kulkarni, V. V., Ware, H. H., Gulraiz, F., Chavez Cavasos, M. A., Martinez Zayas, G., Wali, S., Rice, A. P., Liu, H., Tour, J. M., Sikkema, W. K. A., Cruz Solbes, A. S., Youker, K. A., Tuvim, M. J., Dickey, B. F. & 1 others, Evans, S. E., Mar 1 2019, In : mBio. 10, 2, e00496-19.

Research output: Contribution to journal › Comment/debate

    • Mitochondrial hyperacetylation in the failing hearts of obese patients mediated partly by a reduction in SIRT3: The involvement of the mitochondrial permeability transition pore

    García-Rivas, G., Castillo, E. C., Morales, J. A., Chapoy-Villanueva, H., Silva-Platas, C., Treviño-Saldaña, N., Guerrero-Beltrán, C. E., Bernal-Ramírez, J., Torres-Quintanilla, A., García, N., Youker, K. & Torre-Amione, G., 2019, In : Cellular Physiology and Biochemistry. 53, 3, p. 465-479 15 p.

    Research output: Contribution to journal › Article

    • 3 Scopus citations

    Vulnerable Atherosclerotic Plaque Imaging by Small-Molecule High-Affinity Positron Emission Tomography Radiopharmaceutical

    Yang, Z., Li, F., Yelamanchili, D., Zeng, Z., Rosales, C., Youker, K. A., Shen, H., Ferrari, M., Mahmarian, J., Pownall, H. J., Hamilton, D. J. & Li, Z., Aug 1 2019, In : advanced therapeutics. 2, 8

    Research output: Contribution to journal › Article

    • Efficacy of sustained delivery of GC-1 from a Nanofluidic system in a spontaneously obese non-human primate: a case study

    Filgueira, C. S., Bruno, G., Smith, Z. W., Chua, Y. X., Ballerini, A., Folci, M., Gilbert, A. L., Jain, P., Sastry, J. K., Nehete, P. N., Shelton, K. A., Hill, L. R., Ali, A., Youker, K. A. & Grattoni, A., Jun 1 2018, In : Biomedical Microdevices. 20, 2, 49.

    Research output: Contribution to journal › Article

    • 3 Scopus citations

    Inducible lung epithelial resistance requires multisource reactive oxygen species generation to protect against viral infections

    Kirkpatrick, C. T., Wang, Y., Leiva Juarez, M. M., Shivshankar, P., Pantaleón García, J., Plumer, A. K., Kulkarni, V. V., Ware, H. H., Gulraiz, F., Chavez Cavasos, M. A., Martinez Zayes, G., Wali, S., Rice, A. P., Liu, H., Tour, J. M., Sikkema, W. K. A., Cruz Solbes, A. S., Youker, K. A., Tuvim, M. J., Dickey, B. F. & 1 others, Evans, S. E., May 1 2018, In : mBio. 9, 3, e00696-18.

    Research output: Contribution to journal › Article

    • 4 Scopus citations