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Research Area Keywords
- Neurosciences
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Dive into the research topics where Joy Mitra is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Defining the altered FUS-PARP-1-DNA Ligase III axis and its implications to nuclear and mitochondrial genome damage response in Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD)
Hegde, M. (PI), Hamilton, D. J. (Key Personnel), Horner, P. J. (Key Personnel) & Mitra, J. (Key Personnel)
4/15/20 → 8/31/25
Project: Federal Funding Agencies
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A new conditional TDP¿NLS knock-in mouse model generated using CRISPR/Cas9 technology to study the linkage of TDP-43 pathology to motor and cognitive defects in ALS, FTD and ADRD
Hegde, M. (PI) & Mitra, J. (Key Personnel)
4/15/20 → 2/28/23
Project: Federal Funding Agencies
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TDP-43 pathology â?? mediated DNA Repair Deficiency in Amyotrophic Lateral Sclerosis
Hegde, M. (PI) & Mitra, J. (Key Personnel)
8/1/14 → 7/31/15
Project: Non Profit
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Endogenous TDP-43 mislocalization in a novel knock-in mouse model reveals DNA repair impairment, inflammation, and neuronal senescence
Mitra, J., Kodavati, M., Dharmalingam, P., Guerrero, E. N., Rao, K. S., Garruto, R. M. & Hegde, M. L., Mar 8 2025, In: Acta Neuropathologica Communications. 13, 1, p. 54 54.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Hemin-induced transient senescence via DNA damage response: a neuroprotective mechanism against ferroptosis in intracerebral hemorrhage
Malojirao, V. H., Vasquez, V., Kodavati, M., Mitra, J., Provasek, V., Voh, A. T. T., Liopo, A. V., Derry, P. J., Mikheev, A. M., Rostomily, R. C., Horner, P. J., Tour, J. M., Britz, G. W., Kent, T. A. & Hegde, M. L., Apr 17 2025, In: Communications Biology. 8, 1, p. 622 622.Research output: Contribution to journal › Article › peer-review
Open Access -
FUS unveiled in mitochondrial DNA repair and targeted ligase-1 expression rescues repair-defects in FUS-linked motor neuron disease
Kodavati, M., Wang, H., Guo, W., Mitra, J., Hegde, P. M., Provasek, V., Rao, V. H. M., Vedula, I., Zhang, A., Mitra, S., Tomkinson, A. E., Hamilton, D. J., Van Den Bosch, L. & Hegde, M. L., Mar 9 2024, In: Nature Communications. 15, 1, 2156.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Mitochondria-targeted oligomeric α-synuclein induces TOM40 degradation and mitochondrial dysfunction in Parkinson’s disease and parkinsonism-dementia of Guam
Vasquez, V., Kodavati, M., Mitra, J., Vedula, I., Hamilton, D. J., Garruto, R. M., Rao, K. S. & Hegde, M. L., Dec 2024, In: Cell Death and Disease. 15, 12, 914.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
TDP43 interacts with MLH1 and MSH6 proteins in a DNA damage-inducible manner
Provasek, V. E., Kodavati, M., Kim, B., Mitra, J. & Hegde, M. L., Dec 2024, In: Molecular Brain. 17, 1, 32.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations