Projects per year
Personal profile
Personal profile
Dr. Masdeu trained in Psychiatry at the University of Valencia in Spain and in Neurology at Mt. Sinai Hospital in Chicago. He then served as a Fellow in Neuropathology at Peter Bent Brigham Hospital at Harvard Medical School. He was an Assistant and Associate Professor of Neurology at the Albert Einstein School of Medicine in New York, and has served as a Professor and Chair of Neurology at New York Medical College. Dr. Masdeu became a Professor and Chair of Neurology and Neuroscience at the University of Navarre Medical School in Pamplona, Spain. From 2008-2014, Dr. Masdeu was a senior staff physician and scientist in the Section of Integrative Neuroimaging of the Clinical Brain Disorders Branch at the National Institutes of Health. He is chairman of the Neuroimaging Research Group of the World Federation of Neurology. He has been a director of the American Academy of Neurology and president of the American Society of Neuroimaging. Since 2007, he has been Editor-in-Chief of the Journal of Neuroimaging. He is the author of 144 peer-reviewed papers, 62 book chapters, and seven books, including Localization in Clinical Neurology, a standard in the field, now in its 6th edition. Dr. Masdeu joined the Houston Methodist Research Institute in 2014.
Research interests
Dr. Masdeu’s main areas of research have been the following:
-Clarifying the neurobiology of Alzheimer’s disease and other neurodegenerative disorders
-Using spontaneous lesion models and/or imaging to map the localization of function in the human brain
-Developing novel neuroimaging signs and implementing neuroimaging as a biomarker of neurological disease
Education/Academic qualification
Neuropathology, Postdoctoral Fellowship, Brigham and Women’s Hospital
Neuroscience, PhD, Facultad de Medicina de la Universidad de Navarra, Pamplona
Research Area Keywords
- Neurosciences
Free-text keywords
- Alzheimer’s disease
- Brain lesions
- Neuroimaging
- Psychoses
- Beta-amyloid
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Collaborations and top research areas from the last five years
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A Phase I Clinical Trial, Using Interleukin-2 (IL-2) and Abatacept in Patients with Frontotemporal Disorders
Faridar, A., Appel, S. H., Masdeu, J. C. & Pascual, B.
6/10/24 → …
Project: Clinical Trial
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Biomarker in Aging-Related Disorders (BARD)
Toledo, J. B., Faridar, A., Masdeu, J. C. & Pascual, B.
4/23/24 → …
Project: Clinical Trial
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Selective PET imaging of astrocytes and microglia in Alzheimer's disease
Masdeu, J. C., Pascual, B. & Sangu, M.
1/19/23 → …
Project: Clinical Trial
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Anterior insula is more vulnerable than posterior insula to TDP-43 pathology in common dementias and ALS
Lochner, R. H., Arumanayagam, A. S., Powell, S. Z., Masdeu, J. C., Pascual, B. & Cykowski, M. D., May 1 2024, In: Journal of Neuropathology and Experimental Neurology. 83, 5, p. 307-317 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Examining Associations Between Smartphone Use and Clinical Severity in Frontotemporal Dementia: Proof-of-Concept Study
ALLFTD consortium, 2024, In: JMIR Aging. 7, e52831.Research output: Contribution to journal › Article › peer-review
Open Access -
Reliability and Validity of Smartphone Cognitive Testing for Frontotemporal Lobar Degeneration
Staffaroni, A. M., Clark, A. L., Taylor, J. C., Heuer, H. W., Sanderson-Cimino, M., Wise, A. B., Dhanam, S., Cobigo, Y., Wolf, A., Manoochehri, M., Forsberg, L., Mester, C., Rankin, K. P., Appleby, B. S., Bayram, E., Bozoki, A., Clark, D., Darby, R. R., Domoto-Reilly, K., Fields, J. A., & 30 others , 2024, (Accepted/In press) In: JAMA Network Open. p. E244266Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Research Participants' Perspectives on Precision Diagnostics for Alzheimer's Disease
Smith, H. S., Robinson, J. O., Levchenko, A., Pereira, S., Pascual, B., Bradbury, K., Arbones, V., Fong, J., Shulman, J. M., Mcguire, A. L. & Masdeu, J., Jan 30 2024, In: Journal of Alzheimer's Disease. 97, 3, p. 1261-1274 14 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Advances in the neuroimaging of motor disorders
Weil, E. L., Nakawah, M. O. & Masdeu, J. C., Jan 2023, Handbook of Clinical Neurology. Elsevier B.V., Vol. 195. p. 359-381 23 p. (Handbook of clinical neurology).Research output: Chapter in Book/Report/Conference proceeding › Chapter