Projects per year
Personal profile
Personal profile
Dr. Masdeu trained in Psychiatry at the University of Valencia in Spain and in Neurology at Mt. Sinai Hospital in Chicago. He then served as a Fellow in Neuropathology at Peter Bent Brigham Hospital at Harvard Medical School. He was an Assistant and Associate Professor of Neurology at the Albert Einstein School of Medicine in New York, and has served as a Professor and Chair of Neurology at New York Medical College. Dr. Masdeu became a Professor and Chair of Neurology and Neuroscience at the University of Navarre Medical School in Pamplona, Spain. From 2008-2014, Dr. Masdeu was a senior staff physician and scientist in the Section of Integrative Neuroimaging of the Clinical Brain Disorders Branch at the National Institutes of Health. He is chairman of the Neuroimaging Research Group of the World Federation of Neurology. He has been a director of the American Academy of Neurology and president of the American Society of Neuroimaging. Since 2007, he has been Editor-in-Chief of the Journal of Neuroimaging. He is the author of 144 peer-reviewed papers, 62 book chapters, and seven books, including Localization in Clinical Neurology, a standard in the field, now in its 6th edition. Dr. Masdeu joined the Houston Methodist Research Institute in 2014.
Research interests
Dr. Masdeu’s main areas of research have been the following:
-Clarifying the neurobiology of Alzheimer’s disease and other neurodegenerative disorders
-Using spontaneous lesion models and/or imaging to map the localization of function in the human brain
-Developing novel neuroimaging signs and implementing neuroimaging as a biomarker of neurological disease
Education/Academic qualification
Neuropathology, Postdoctoral Fellowship, Brigham and Women’s Hospital
Neuroscience, PhD, Facultad de Medicina de la Universidad de Navarra, Pamplona
Research Area Keywords
- Neurosciences
Free-text keywords
- Alzheimer’s disease
- Brain lesions
- Neuroimaging
- Psychoses
- Beta-amyloid
Fingerprint
- 1 Similar Profiles
Collaborations and top research areas from the last five years
-
A Phase I Clinical Trial, Using Interleukin-2 (IL-2) and Abatacept in Patients with Frontotemporal Disorders
Faridar, A. (PI), Appel, S. H. (Key Personnel), Masdeu, J. C. (Key Personnel) & Pascual, B. (Key Personnel)
6/10/24 → …
Project: Clinical Trial
-
Biomarker in Aging-Related Disorders (BARD)
Toledo, J. B. (PI), Faridar, A. (Key Personnel), Masdeu, J. C. (Key Personnel) & Pascual, B. (Key Personnel)
4/23/24 → …
Project: Clinical Trial
-
Veri-T: A Phase 1, Randomized, Double-Blind, Placebo- Controlled, Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy Study of Oral Verdiperstat (BHV-3241) in Patients With Semantic Variant Primary Progressive Aphasia (svPPA
Masdeu, J. C. (PI)
6/15/23 → 9/30/25
Project: Non Profit
-
Selective PET imaging of astrocytes and microglia in Alzheimer's disease
Masdeu, J. C. (PI), Pascual, B. (Key Personnel) & Sangu, M. (Key Personnel)
1/19/23 → …
Project: Clinical Trial
-
Alzheimer?s Disease Neuroimaging Initiative 4 (ADNI4)
Masdeu, J. C. (PI)
9/15/22 → 7/31/25
Project: Non Profit
-
Brain aging rejuvenation factors in adults with genetic and sporadic neurodegenerative disease
Casaletto, K. B., Saloner, R., Kornak, J., Staffaroni, A. M., Villeda, S., Paolillo, E., VandeBunte, A. M., Cadwallader, C. J., Lario Lago, A., Webb, J., Chen, C., Rascovsky, K., Miyagawa, T., Ramos, E. M., Masdeu, J. C., Pantelyat, A., Tartaglia, M. C., Bozoki, A., Pressman, P. S. & Rademakers, R. & 25 others, , 2025, In: Brain Communications. 7, 1, fcae432.Research output: Contribution to journal › Article › peer-review
Open Access -
Brain inflammation co-localizes highly with tau in mild cognitive impairment due to early-onset Alzheimer's disease
Appleton, J., Finn, Q., Zanotti-Fregonara, P., Yu, M., Faridar, A., Nakawah, M. O., Zarate, C., Carrillo, M. C., Dickerson, B. C., Rabinovici, G. D., Apostolova, L. G., Masdeu, J. C. & Pascual, B., Jan 1 2025, In: Brain. 148, 1, p. 119-132 14 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Differences in baseline cognitive performance between participants with early-onset and late-onset Alzheimer's disease: Comparison of LEADS and ADNI
the LEADS Consortium 1 for the Alzheimer's Disease Neuroimaging Initiative, Jan 2025, In: Alzheimer's and Dementia. 21, 1, e14218.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
État Criblé: High-Resolution MRI and Metabolism
Alzheimer Disease Neuroimaging Initiative, Feb 25 2025, In: Neurology. 104, 4, p. e213358Research output: Contribution to journal › Article › peer-review
-
The POINTER Imaging baseline cohort: Associations between multimodal neuroimaging biomarkers, cardiovascular health, and cognition
for the U.S. POINTER Study Group, Jan 2025, In: Alzheimer's and Dementia. 21, 1, e14399.Research output: Contribution to journal › Article › peer-review
Open Access