John P. Cooke, MD, PhD

Projects

Projects per year 2013 2013 2015 2019 2020 2025

• 8 Active
• 25 Finished

Projects per year

Search results

• Active

  Determinants of COVID19-induced venous thrombosis and targeted therapy assessed with bioengineered Vein-Chip.

  Cooke, J. P.

  5/1/21 → 4/30/25

  Project: Federal Funding Agencies

• RE-ENERGIZE FONTAN - RandomizEd Exercise INtERvention desiGned to MaximIZE Fitness in Pediatric FONTAN patients

  Cooke, J. P.

  3/26/21 → 2/28/25

  Project: Federal Funding Agencies

• CPRIT RNA Therapeutics Core

  Cooke, J. P., Godin, B. & Kiss, D. L.

  8/31/20 → 8/30/25

  Project: State

• Reversal of Heart Failure: Role of Vascular Recovery

  Cooke, J. P. & Youker, K. A.

  7/15/20 → 3/31/24

  Project: Federal Funding Agencies

• Targeting novel checkpoint regulator to control viral myocarditis

  Xing, J., Cooke, J. P., Li, X. C. & Zhang, Z.

  7/1/20 → 6/30/23

  Project: Non Profit

• Exercise Intervention for Strong and Fit Pediatric Fontan Patients (StrongFitFontan)

  Cooke, J. P.

  3/10/20 → 2/28/25

  Project: Federal Funding Agencies

• Pathological flow-induced endothelial damage and plaque erosion

  Cooke, J. P. & Le, N.

  7/15/19 → 6/30/23

  Project: Federal Funding Agencies

• Long non-coding RNA mediated chromatin remodeling in angiogenesis

  Cooke, J. P.

  7/1/19 → 6/30/24

  Project: Federal Funding Agencies

• Finished

  Nanozyme Therapy for Chronic Venous Stasis Dermatitis: New Approach for a Major Unmet Clinical Need

  Cooke, J. P.

  4/1/21 → 3/31/23

  Project: Federal Funding Agencies

• Computational epigenetics modeling of cell identity genes

  Cooke, J. P.

  11/1/20 → 12/31/22

  Project: Federal Funding Agencies

• Biodegradability and Biocompatiblity of a Shape Memory Polymer Wrap to Improve Saphenous Vein Graft Patency in Peripheral and Coronary Artery Bypass Grafting Surgeries

  Peden, E. K., Cooke, J. P. & Karmonik, C.

  4/15/20 → 10/31/21

  Project: Federal Funding Agencies

• A NOVEL HISTONE MODIFICATION MEDIATES DNA ACCESSIBILITY: ROLE OF INOS

  Cooke, J. P.

  1/1/20 → 12/31/21

  Project: Non Profit

• Hemodynamic Optimization and Preclinical Assessment of a Shape Memory Polymer Wrap to Reduce Hemodialysis Access Site Failures

  Peden, E. K., Cooke, J. P. & Karmonik, C.

  10/1/19 → 4/30/22

  Project: Federal Funding Agencies

• The role of steroid receptor coactivator-2 in coordinating stress-activated angiogenesis in the myocardium

  Pownall, H. J., Blanco, E. & Cooke, J. P.

  7/1/19 → 6/30/22

  Project: Non Profit

• Computational epigenetics modeling of cell identity genes

  Cao, Q., Cooke, J. P. & Fang, L.

  7/1/18 → 11/1/20

  Project: Federal Funding Agencies

• Role of S-nitrosylation in Transdifferentiation

  Cooke, J. P. & Cao, Q.

  4/1/18 → 11/30/22

  Project: Federal Funding Agencies

• Transdifferentiation of fibroblasts to endothelial cells contributes to angiogenesis - Role of TLR3 signaling

  Cooke, J. P. & Pownall, H. J.

  7/1/17 → 9/30/20

  Project: Non Profit

• Identification of transcriptional/epigenetic facilitators and barriers to nuclear reprogramming by single cell RNA-sequencing within and outside the ?Goldilocks? zone?

  Cooke, J. P.

  University of Maryland

  5/1/16 → 4/30/17

  Project: Federal Funding Agencies

• AIBP Mediates a Novel Interplay between Cholesterol Metabolism and Lymphangiogenesis

  Fang, L., Cooke, J. P. & Pownall, H. J.

  National Heart Lung and Blood Institute

  4/1/16 → 1/31/22

  Project: Federal Funding Agencies

• Telomerase Therapy for Progeria

  Cooke, J. P.

  The Progeria Research Foundation

  9/1/15 → 2/28/17

  Project: Non Profit

• Role of Sirtuins in macrophage-mediated regeneration in the diabetic heart

  Cooke, J. P. & Amirthalingam Thandavarayan, R.

  American Heart Association

  7/1/15 → 6/30/17

  Project: Non Profit

• Referral site for Cardiovascular Cell Therapy Research Network (CCTRN)

  Cooke, J. P.

  Texas Heart Institute

  7/1/15 → 2/28/16

  Project: Non Profit

• CPRIT Core for RNA Therapeutics and Research

  Cooke, J. P. & Wang, R.

  Cancer Prevention and Res Inst of Texas

  6/1/15 → 11/30/20

  Project: State

• Transdifferentiation of Functional Endothelial Cells from Fibroblasts Using Small Molecules

  Cooke, J. P.

  American Heart Association

  1/1/15 → 12/31/16

  Project: Non Profit

• DDAH as a Novel Target in Pulmonary Fibrosis

  Cooke, J. P.

  National Heart Lung and Blood Institute

  3/15/14 → 2/13/16

  Project: Federal Funding Agencies

• The Role of the Nicotinic Cholinergic Pathway in Retinopathy of Prematurity

  Cooke, J. P.

  National Eye Institute

  9/1/13 → 8/31/15

  Project: Federal Funding Agencies

• Telomere extension using nucleoside-modified mRNA and exosomes as a novel therapeutic approach

  Cooke, J. P.

  Stanford University

  9/1/13 → 5/31/15

  Project: Federal Funding Agencies

• Basic and Translational Research of iPSC-Based Hematologic and Vascular Therapies

  Cooke, J. P.

  National Heart Lung and Blood Institute

  8/8/13 → 10/31/17

  Project: Federal Funding Agencies

• Safe, Rapid Telomere Extension to Prevent and Treate Hypertension

  Cooke, J. P.

  Stanford University

  7/1/13 → 4/30/15

  Project: Federal Funding Agencies

• Transflammation: Its Role in Direct Reprogramming

  Cooke, J. P. & Sayed, N.

  Univ of Maryland, Baltimore

  7/1/13 → 4/30/16

  Project: Federal Funding Agencies

• RNAcore for the Progenitor Cell Biology Consortium

  Cooke, J. P.

  Univ of Maryland, Baltimore

  7/1/13 → 4/30/17

  Project: Federal Funding Agencies

• Safe, rapid telomere extension in diverse progenitor cell types using nucleoside-modified mRNA encoding telomerase

  Cooke, J. P.

  Stanford University

  5/1/13 → 8/31/14

  Project: Federal Funding Agencies

• Cell Characterization and Imaging for Regenerative Therapies in Ischemic Diseases

  Cooke, J. P.

  Stanford University

  3/1/13 → 2/28/15

  Project: Federal Funding Agencies