Jenny C. Chang

2022

A comparative efficacy study of diagnostic digital breast tomosynthesis and digital mammography in BI-RADS 4 breast cancer diagnosis

Ezeana, C. F., Puppala, M., Wang, L., Chang, J. C. & Wong, S. T. C., Aug 2022, In: European Journal of Radiology. 153, 110361.

Research output: Contribution to journal › Article › peer-review

Open Access

A Phase 2 Trial of Enhancing Immune Checkpoint Blockade by Stereotactic Radiation and In Situ Virus Gene Therapy in Metastatic Triple-Negative Breast Cancer

Sun, K., Xu, Y., Zhang, L., Niravath, P., Darcourt, J., Patel, T., Teh, B. S., Farach, A. M., Guerrero, C., Mathur, S., Sultenfuss, M. A., Gupta, N., Schwartz, M. R., Haley, S. L., Nair, S., Li, X., Nguyen, T. T. A., Butner, J. D., Ensor, J., Mejia, J. A., & 5 othersMei, Z., Butler, E. B., Chen, S. H., Bernicker, E. H. & Chang, J. C., Oct 14 2022, In: Clinical cancer research : an official journal of the American Association for Cancer Research. 28, 20, p. 4392-4401 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Clinical factors and association with treatment modalities in patients with breast cancer and brain metastases who develop leptomeningeal metastases

Puri, A., Mylavarapu, C., Xu, J., Patel, T. A., S.Teh, B., Tremont-Lukats, I., Chang, J. C. & Niravath, P., Jun 2022, In: Breast Cancer Research and Treatment. 193, 3, p. 613-623 11 p.

Research output: Contribution to journal › Article › peer-review

Systemic Nos2 Depletion and Cox inhibition limits TNBC disease progression and alters lymphoid cell spatial orientation and density

Somasundaram, V., Ridnour, L. A., Cheng, R. Y., Walke, A. J., Kedei, N., Bhattacharyya, D. D., Wink, A. L., Edmondson, E. F., Butcher, D., Warner, A. C., Dorsey, T. H., Scheiblin, D. A., Heinz, W., Bryant, R. J., Kinders, R. J., Lipkowitz, S., Wong, S. T., Pore, M., Hewitt, S. M., McVicar, D. W., & 6 othersAnderson, S. K., Chang, J., Glynn, S. A., Ambs, S., Lockett, S. J. & Wink, D. A., Dec 2022, In: Redox Biology. 58, p. 102529

Research output: Contribution to journal › Article › peer-review

Tocilizumab overcomes chemotherapy resistance in mesenchymal stem-like breast cancer by negating autocrine IL-1A induction of IL-6

Chung, A. W., Kozielski, A. J., Qian, W., Zhou, J., Anselme, A. C., Chan, A. A., Pan, P. Y., Lee, D. J. & Chang, J. C., Dec 2022, In: npj Breast Cancer. 8, 1, 30.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

Utility of Cell-Free DNA Detection in Transplant Oncology

Reddy, T., Esmail, A., Chang, J. C., Ghobrial, R. M. & Abdelrahim, M., Feb 1 2022, In: Cancers. 14, 3, 743.

Research output: Contribution to journal › Review article › peer-review

Open Access

8 Scopus citations

Utilization of Immunotherapy for the Treatment of Hepatocellular Carcinoma in the Peri-Transplant Setting: Transplant Oncology View

Abdelrahim, M., Esmail, A., Saharia, A., Abudayyeh, A., Abdel-Wahab, N., Diab, A., Murakami, N., Kaseb, A. O., Chang, J. C., Gaber, A. O. & Ghobrial, R. M., Apr 1 2022, In: Cancers. 14, 7, 1760.

Research output: Contribution to journal › Review article › peer-review

Open Access

11 Scopus citations

Vitamin E Enhances Cancer Immunotherapy by Reinvigorating Dendritic Cells via Targeting Checkpoint SHP1

Yuan, X., Duan, Y., Xiao, Y., Sun, K., Qi, Y., Zhang, Y., Ahmed, Z., Moiani, D., Yao, J., Li, H., Zhang, L., Yuzhalin, A. E., Li, P., Zhang, C., Badu-Nkansah, A., Saito, Y., Liu, X., Kuo, W. L., Ying, H., Sun, S. C., & 3 othersChang, J. C., Tainer, J. A. & Yu, D., Jul 1 2022, In: Cancer Discovery. 12, 7, p. 1743-1759 17 p.

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

2021

Acetyl-CoA Synthetase 2: A Critical Linkage in Obesity-Induced Tumorigenesis in Myeloma

Li, Z., Liu, H., He, J., Wang, Z., Yin, Z., You, G., Wang, Z., Davis, R. E., Lin, P., Bergsagel, P. L., Manasanch, E. E., Wong, S. T. C., Esnaola, N. F., Chang, J. C., Orlowski, R. Z., Yi, Q. & Yang, J., Jan 5 2021, In: Cell Metabolism. 33, 1, p. 78-93.e7

Research output: Contribution to journal › Article › peer-review

Open Access

26 Scopus citations

Analysis of the Implementation of Telehealth Visits for Care of Patients With Cancer in Houston During the COVID-19 Pandemic

Darcourt, J. G., Aparicio, K., Dorsey, P. M., Ensor, J. E., Zsigmond, E. M., Wong, S. T., Ezeana, C. F., Puppala, M., Heyne, K. E., Geyer, C. E., Phillips, R. A., Schwartz, R. L. & Chang, J. C., Jan 1 2021, In: JCO oncology practice. 17, 1, p. e36-e43

Research output: Contribution to journal › Article › peer-review

Open Access

53 Scopus citations

ANETT: PhAse II trial of NEoadjuvant TAK-228 plus Tamoxifen in patients with hormone receptor-positive breast cancer

Koca, E., Niravath, P. A., Ensor, J., Patel, T. A., Li, X., Hemati, P., Wong, H., Qian, W., Boone, T., Zhao, J., Ramshesh, P. V., Cohen, A. L., Murthy, A., Nair, S., Darcourt, J. G., Belcheva, A., Kaklamani, V. G. & Chang, J. C. N., Jul 2021, In: Breast Cancer Research and Treatment. 188, 2, p. 433-439 7 p.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

A phase 1/2 clinical trial of the nitric oxide synthase inhibitor L-NMMA and taxane for treating chemoresistant triple-negative breast cancer

Chung, A. W., Anand, K., Anselme, A. C., Chan, A. A., Gupta, N., Venta, L. A., Schwartz, M. R., Qian, W., Xu, Y., Zhang, L., Kuhn, J., Patel, T., Rodriguez, A. A., Belcheva, A., Darcourt, J., Ensor, J., Bernicker, E., Pan, P. Y., Chen, S. H., Lee, D. J., & 2 othersNiravath, P. A. & Chang, J. C., Dec 15 2021, In: Science translational medicine. 13, 624, abj5070.

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

A Phase II Study of the Efficacy and Safety of Chloroquine in Combination With Taxanes in the Treatment of Patients With Advanced or Metastatic Anthracycline-refractory Breast Cancer

Anand, K., Niravath, P., Patel, T., Ensor, J., Rodriguez, A., Boone, T., Wong, S. T. & Chang, J. C., Jun 2021, In: Clinical Breast Cancer. 21, 3, p. 199-204 6 p.

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

A randomized, placebo-controlled phase 2 study of paclitaxel in combination with reparixin compared to paclitaxel alone as front-line therapy for metastatic triple-negative breast cancer (fRida)

for the fRida Trial Investigators, Nov 2021, In: Breast Cancer Research and Treatment. 190, 2, p. 265-275 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

19 Scopus citations

A targetable LIFR−NF-κB−LCN2 axis controls liver tumorigenesis and vulnerability to ferroptosis

Yao, F., Deng, Y., Zhao, Y., Mei, Y., Zhang, Y., Liu, X., Martinez, C., Su, X., Rosato, R. R., Teng, H., Hang, Q., Yap, S., Chen, D., Wang, Y., Chen, M. J. M., Zhang, M., Liang, H., Xie, D., Chen, X., Zhu, H., & 5 othersChang, J. C., You, M. J., Sun, Y., Gan, B. & Ma, L., Dec 2021, In: Nature Communications. 12, 1, 7333.

Research output: Contribution to journal › Article › peer-review

Open Access

34 Scopus citations

Benchmarks for Academic Oncology Faculty

Anthony, L., Atweh, G., Bhatia, R., Carey, L. A., Chang, J. C., Edelman, M. J., Kantoff, P. W., Markham, M. J., Messersmith, W., Nelson, E. L., Oettel, K., O'Regan, R., Verschraegen, C. F. & Vose, J. M., Mar 1 2021, In: JCO oncology practice. 17, 3, p. e440-e444

Research output: Contribution to journal › Review article › peer-review

Enhancing Inflammation Targeting Using Tunable Leukocyte-Based Biomimetic Nanoparticles

Zinger, A., Sushnitha, M., Naoi, T., Baudo, G., De Rosa, E., Chang, J., Tasciotti, E. & Taraballi, F., Apr 27 2021, In: ACS Nano. 15, 4, p. 6326-6339 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

24 Scopus citations

Measuring Ovarian Escape in Premenopausal Estrogen Receptor-Positive Breast Cancer Patients on Ovarian Suppression Therapy

Burns, E., Koca, E., Xu, J., McLean, E., Lee, R., Patel, T., Chang, J. & Niravath, P., Jun 2021, In: Oncologist. 26, 6, p. e936-e942

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Sacituzumab govitecan, a Trop-2-directed antibody-drug conjugate, for patients with epithelial cancer: final safety and efficacy results from the phase I/II IMMU-132-01 basket trial

Bardia, A., Messersmith, W. A., Kio, E. A., Berlin, J. D., Vahdat, L., Masters, G. A., Moroose, R., Santin, A. D., Kalinsky, K., Picozzi, V., O'Shaughnessy, J., Gray, J. E., Komiya, T., Lang, J. M., Chang, J. C., Starodub, A., Goldenberg, D. M., Sharkey, R. M., Maliakal, P., Hong, Q., & 3 othersWegener, W. A., Goswami, T. & Ocean, A. J., Jun 2021, In: Annals of Oncology. 32, 6, p. 746-756 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

65 Scopus citations

Targeting mTOR and DNA repair pathways in residual triple negative breast cancer post neoadjuvant chemotherapy

Anand, K., Patel, T., Niravath, P., Rodriguez, A., Darcourt, J., Belcheva, A., Boone, T., Ensor, J. & Chang, J., Jan 8 2021, In: Scientific Reports. 11, 1, 82.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

2020

A comprehensive overview of metaplastic breast cancer: clinical features and molecular aberrations

Reddy, T. P., Rosato, R. R., Li, X., Moulder, S., Piwnica-Worms, H. & Chang, J. C., Nov 4 2020, In: Breast Cancer Research. 22, 1, 121.

Research output: Contribution to journal › Review article › peer-review

Open Access

38 Scopus citations

A Deep Learning-Based Decision Support Tool for Precision Risk Assessment of Breast Cancer

He, T., Puppala, M., Ezeana, C. F., Huang, Y-S., Chou, P-H., Yu, X., Chen, S., Wang, L., Yin, Z., Danforth, R. L., Ensor, J., Chang, J., Patel, T. & Wong, S. T. C., Jan 2020, In: JCO Clinical Cancer Informatics. 3, p. 1-12 12 p.

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Antihistamine drug ebastine inhibits cancer growth by targeting polycomb group protein EZH2

Li, Q., Liu, K. Y., Liu, Q., Wang, G., Jiang, W., Meng, Q., Yi, Y., Yang, Y., Wang, R., Zhu, S., Li, C., Wu, L., Zhao, D., Yan, L., Zhang, L., Kim, J. S., Zu, X., Kozielski, A. J., Qian, W., Chang, J. C., & 3 othersPatnaik, A., Chen, K. & Cao, Q., Oct 1 2020, In: Molecular Cancer Therapeutics. 19, 10, p. 2023-2033 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

A window-of-opportunity trial of the CXCR1/2 inhibitor reparixin in operable HER-2-negative breast cancer

Goldstein, L. J., Perez, R. P., Yardley, D., Han, L. K., Reuben, J. M., Gao, H., McCanna, S., Butler, B., Ruffini, P. A., Liu, Y., Rosato, R. R. & Chang, J. C., Jan 10 2020, In: Breast Cancer Research. 22, 1, 4.

Research output: Contribution to journal › Article › peer-review

Open Access

45 Scopus citations

Clinical evaluation of germline polymorphisms associated with capecitabine toxicity in breast cancer: TBCRC-015

the Translational Breast Cancer Research Consortium (TBCRC), Jun 1 2020, In: Breast Cancer Research and Treatment. 181, 3, p. 623-633 11 p.

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Correction to: A window-of-opportunity trial of the CXCR1/2 inhibitor reparixin in operable HER-2-negative breast cancer (Breast Cancer Research (2020) 22: 4 DOI: 10.1186/s13058-019-1243-8)

Goldstein, L. J., Perez, R. P., Yardley, D., Han, L. K., Reuben, J. M., Gao, H., McCanna, S., Butler, B., Ruffini, P. A., Liu, Y., Rosato, R. R. & Chang, J. C., May 20 2020, In: Breast Cancer Research. 22, 1, 52.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Emerging treatment strategies for breast cancer brain metastasis: from translational therapeutics to real-world experience

Ren, D., Cheng, H., Wang, X., Vishnoi, M., Teh, B. S., Rostomily, R., Chang, J. C., Wong, S. T. & Zhao, H., Jun 30 2020, (E-pub ahead of print) In: Therapeutic Advances in Medical Oncology. 12

Research output: Contribution to journal › Review article › peer-review

Open Access

12 Scopus citations

Erratum: Bromodomain and extraterminal protein inhibition blocks growth of triple-negative breast cancers through the suppression of aurora kinases (J. Biol. Chem. (2016) 291 (23756-23768) DOI: 10.1074/jbc.M116.738666)

Sahni, J. M., Gayle, S. S., Weber Bonk, K. L., Vite, L. C., Yori, J. L., Webb, B., Ramos, E. K., Seachrist, D. D., Landis, M. D., Chang, J. C., Bradner, J. E. & Keri, R. A., Jul 3 2020, In: Journal of Biological Chemistry. 295, 27, p. 9266 1 p.

Research output: Contribution to journal › Comment/debate › peer-review

Open Access

1 Scopus citations

Inhibition of EZH2 Catalytic Activity Selectively Targets a Metastatic Subpopulation in Triple-Negative Breast Cancer

Yomtoubian, S., Lee, S. B., Verma, A., Izzo, F., Markowitz, G., Choi, H., Cerchietti, L., Vahdat, L., Brown, K. A., Andreopoulou, E., Elemento, O., Chang, J., Inghirami, G., Gao, D., Ryu, S. & Mittal, V., Jan 21 2020, In: Cell Reports. 30, 3, p. 755-770.e6

Research output: Contribution to journal › Article › peer-review

49 Scopus citations

MEK activation modulates glycolysis and supports suppressive myeloid cells in TNBC

Franklin, D. A., Sharick, J. T., Ericsson-Gonzalez, P. I., Sanchez, V., Dean, P. T., Opalenik, S. R., Cairo, S., Judde, J. G., Lewis, M. T., Chang, J. C., Sanders, M. E., Cook, R. S., Skala, M. C., Bordeaux, J., Orozco Bender, J., Vaupel, C., Geiss, G., Hinerfeld, D. & Balko, J. M., Aug 6 2020, In: JCI insight. 5, 15, e134290.

Research output: Contribution to journal › Article › peer-review

Open Access

12 Scopus citations

Metastatic triple-negative breast cancer: Established and emerging treatments

Puri, A., Reddy, T. P., Patel, T. A. & Chang, J. C., Sep 2020, In: Breast Journal. 26, 9, p. 1793-1796 4 p.

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Simultaneous targeting of HER family pro-survival signaling with Pan-HER antibody mixture is highly effective in TNBC: a preclinical trial with PDXs

Reddy, T. P., Choi, D. S., Anselme, A. C., Qian, W., Chen, W., Lantto, J., Horak, I. D., Kragh, M., Chang, J. C. & Rosato, R. R., May 15 2020, In: Breast cancer research : BCR. 22, 1, p. 48 1 p.

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

2019

A combinatorial biomarker predicts pathologic complete response to neoadjuvant lapatinib and trastuzumab without chemotherapy in patients with HER2+ breast cancer

Veeraraghavan, J., De Angelis, C., Mao, R., Wang, T., Herrera, S., Pavlick, A. C., Contreras, A., Nuciforo, P., Mayer, I. A., Forero, A., Nanda, R., Goetz, M. P., Chang, J. C., Wolff, A. C., Krop, I. E., Fuqua, S. A. W., Prat, A., Hilsenbeck, S. G., Weigelt, B., Reis-Filho, J. S., & 4 othersGutierrez, C., Osborne, C. K., Rimawi, M. F. & Schiff, R., Jun 1 2019, In: Annals of Oncology. 30, 6, p. 927-933 7 p., mdz076.

Research output: Contribution to journal › Article › peer-review

Open Access

29 Scopus citations

A randomized, controlled phase II trial of neoadjuvant ado-trastuzumab emtansine, lapatinib, and nab-paclitaxel versus trastuzumab, pertuzumab, and paclitaxel in HER2-positive breast cancer (TEAL study)

Patel, T., Ensor, Jr., J. E., Creamer, S. L., Boone, T., Rodriguez, A. A., Niravath, P. A., Darcourt, J., Meisel, J. L., Li, X., Zhao, J., Kuhn, J. G., Rosato, R. R., Qian, W., Belcheva, A., Schwartz, M. R., Kaklamani, V. G. & Chang, J. C., Sep 2 2019, In: Breast Cancer Research. 21, 1, 100.

Research output: Contribution to journal › Article › peer-review

Open Access

23 Scopus citations

Autophagy inhibition elicits emergence from metastatic dormancy by inducing and stabilizing Pfkfb3 expression

La Belle Flynn, A., Calhoun, B. C., Sharma, A., Chang, J. C., Almasan, A. & Schiemann, W. P., Aug 14 2019, In: Nature Communications. 10, 1, 3668.

Research output: Contribution to journal › Article › peer-review

Open Access

70 Scopus citations

Cancer therapeutic targeting using mutant–p53-specific siRNAs

Ubby, I., Krueger, C., Rosato, R., Qian, W., Chang, J. & Sabapathy, K., May 2 2019, In: Oncogene. 38, 18, p. 3415-3427 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

20 Scopus citations

Detection of breast cancer stem cell gene mutations in circulating free DNA during the evolution of metastases

Liu, Z. B., Ezzedine, N. E., Eterovic, A. K., Ensor, Jr., J. E., Huang, H. J., Albanell, J., Choi, D. S., Lluch, A., Liu, Y., Rojo, F., Wong, H., Martínez-Dueñas, E., Guerrero-Zotano, Á., Shao, Z. M., Darcourt, J., Mills, G. B., Dave, B. & Chang, J. C., Nov 1 2019, In: Breast Cancer Research and Treatment. 178, 2, p. 251-261 11 p.

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Developing a model to predict accrual to cancer clinical trials: Data from an NCI designated cancer center

Iruku, P., Goros, M., Gelfond, J., Chang, J., Padalecki, S., Mesa, R. & Kaklamani, V. G., Sep 2019, In: Contemporary Clinical Trials Communications. 15, 100421.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Erratum: Triple-negative breast cancers with amplication of JAK2 at the 9p24 locus demonstrate JAK2-specic dependence (Science Translational Medicine (2019) 11, 476, (eaaw6162), 10.1126/scitranslmed.aaw6162)

Balko, J. M., Schwarz, L. J., Luo, N., Estrada, M. V., Giltnane, J. M., Dávila-González, D., Wang, K., Sánchez, V., Dean, P. T., Combs, S. E., Hicks, D., Pinto, J. A., Landis, M. D., Doimi, F. D., Yelensky, R., Miller, V. A., Stephens, P. J., Rimm, D. L., Gómez, H., Chang, J. C., & 3 othersSanders, M. E., Cook, R. S. & Arteaga, C. L., Jan 23 2019, In: Science translational medicine. 11, 476, eaaw6162.

Research output: Contribution to journal › Review article › peer-review

Hydroxytyrosol inhibits cancer stem cells and the metastatic capacity of triple-negative breast cancer cell lines by the simultaneous targeting of epithelial-to-mesenchymal transition, Wnt/β-catenin and TGFβ signaling pathways

Cruz-Lozano, M., González-González, A., Marchal, J. A., Muñoz-Muela, E., Molina, M. P., Cara, F. E., Brown, A. M., García-Rivas, G., Hernández-Brenes, C., Lorente, J. A., Sanchez-Rovira, P., Chang, J. C. & Granados-Principal, S., Dec 1 2019, In: European Journal of Nutrition. 58, 8, p. 3207-3219 13 p.

Research output: Contribution to journal › Article › peer-review

30 Scopus citations

Prognosis of lymphotropic invasive micropapillary breast carcinoma analyzed by using data from the National Cancer Database

Lewis, G. D., Xing, Y., Haque, W. M., Patel, T., Schwartz, M., Chen, A., Farach, A. M., Hatch, S. S., Butler, E. B., Chang, J. C. & Teh, B. S., Oct 21 2019, In: Cancer Communications. 39, 1, 60.

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

The impact of molecular status on survival outcomes for invasive micropapillary carcinoma of the breast

Lewis, G. D., Xing, Y., Haque, W. M., Patel, T., Schwartz, M. R., Chen, A. C., Farach, A. M., Hatch, S. S., Butler, E. B., Chang, J. C. & Teh, B. S., Nov 1 2019, In: Breast Journal. 25, 6, p. 1171-1176 6 p.

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

2018

A Behavior-Modification, Clinical-Grade Mobile Application to Improve Breast Cancer Survivors' Accountability and Health Outcomes

Stubbins, R., He, T., Yu, X., Puppala, M., Ezeana, C. F., Chen, S., Valdivia y Alvarado, M., Ensor, J., Rodriguez, A., Niravath, P., Chang, J., Wong, S. T. C. & Patel, T., Nov 1 2018, In: JCO Clinical Cancer Informatics. 2, p. 1-11 11 p.

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Activating Transcription Factor 4 Modulates TGFβ-Induced Aggressiveness in Triple-Negative Breast Cancer via SMAD2/3/4 and mTORC2 Signaling

González-González, A., Muñoz-Muela, E., Marchal, J. A., Cara, F. E., Molina, M. P., Cruz-Lozano, M., Jiménez, G., Verma, A., Ramírez, A., Qian, W., Chen, W., Kozielski, A. J., Elemento, O., Martín-Salvago, M. D., Luque, R. J., Rosa-Garrido, C., Landeira, D., Quintana-Romero, M., Rosato, R. R., García, M. A., & 9 othersRamirez-Tortosa, C. L., Kim, H., Rodriguez-Aguayo, C., Lopez-Berestein, G., Sood, A. K., Lorente, J. A., Sánchez-Rovira, P., Chang, J. C. & Granados-Principal, S., Nov 15 2018, In: Clinical Cancer Research. 24, 22, p. 5697-5709 13 p.

Research output: Contribution to journal › Article › peer-review

30 Scopus citations

Evaluation of anti-PD-1-based therapy against triple-negative breast cancer patient-derived xenograft tumors engrafted in humanized mouse models

Rosato, R. R., Dávila-González, D., Choi, D. S., Qian, W., Chen, W., Kozielski, A. J., Wong, H., Dave, B. & Chang, J. C., Sep 5 2018, In: Breast Cancer Research. 20, 1, 108.

Research output: Contribution to journal › Article › peer-review

57 Scopus citations

Low PETN levels and PIK3CA mutations predict resistance to neoadjuvant lapatinib and trastuzumab without chemotherapy in patients with HER2 over-expressing breast cancer

Rimawi, M. F., de Angelis, C., Contreras, A., Pareja, F., Geyer, F. C., Burke, K. A., Herrera, S., Wang, T., Mayer, I. A., Forero, A., Nanda, R., Goetz, M. P., Chang, J. C., Krop, I. E., Wolff, A. C., Pavlick, A. C., Fuqua, S. A. W., Gutierrez, C., Hilsenbeck, S. G., Li, M. M., & 4 othersWeigelt, B., Reis-Filho, J. S., Kent Osborne, C. & Schiff, R., Nov 7 2018, In: Breast Cancer Research and Treatment. 167, 3, p. 731-740 10 p.

Research output: Contribution to journal › Article › peer-review

53 Scopus citations

Pharmacological inhibition of NOS activates ASK1/JNK pathway augmenting docetaxel-mediated apoptosis in triple-negative breast cancer

Davila-Gonz alez, D., Choi, D. S., Rosato, R. R., Granados-Principal, S. M., Kuhn, J. G., Li, W. F., Qian, W., Chen, W., Kozielski, A. J., Wong, H., Dave, B. & Chang, J. C., Mar 1 2018, In: Clinical Cancer Research. 24, 5, p. 1152-1162 11 p.

Research output: Contribution to journal › Article › peer-review

51 Scopus citations

The ERβ4 variant induces transformation of the normal breast mammary epithelial cell line MCF-10A; the ERβ variants ERβ2 and ERβ5 increase aggressiveness of TNBC by regulation of hypoxic signaling

Faria, M., Karami, S., Granados-Principal, S., Dey, P., Verma, A., Choi, D. S., Elemento, O., Bawa-Khalfe, T., Chang, J. C., Strom, A. M. & Gustafsson, J. Å., 2018, In: Oncotarget. 9, 15, p. 12201-12211 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

Treatment Outcomes and Prognostic Factors in Male Patients With Stage IV Breast Cancer: A Population-based Study

Chen, W., Huang, Y., Lewis, G. D., Szeja, S. S., Hatch, S. S., Farach, A., Miltenburg, D., Butler, E. B., Chang, J. C. & Teh, B. S., Feb 2018, In: Clinical Breast Cancer. 18, 1, p. e97-e105

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

2017

A randomized phase II neoadjuvant study of cisplatin, paclitaxel with or without everolimus in patients with stage II/III triple-negative breast cancer (TNBC): Responses and long-term outcome correlated with increased frequency of DNA damage response gene mutations, TNBC subtype, AR status, and Ki67

Jovanovic, B., Mayer, I. A., Mayer, E. L., Abramson, V. G., Bardia, A., Sanders, M. E., Kuba, M. G., Estrada, M. V., Beeler, J. S., Shaver, T. M., Johnson, K. C., Sanchez, V., Rosenbluth, J. M., Dillon, P. M., Forero-Torres, A., Chang, J. C., Meszoely, I. M., Grau, A. M., Lehmann, B. D., Shyr, Y., & 4 othersSheng, Q., Chen, S. C., Arteaga, C. L. & Pietenpol, J. A., Aug 1 2017, In: Clinical Cancer Research. 23, 15, p. 4035-4045 11 p.

Research output: Contribution to journal › Article › peer-review

83 Scopus citations

Jenny C. Chang, MD

Research output

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