Jenny C. Chang, MD

Projects

Projects per year 2010 2014 2016 2020 2045

• 23 Active
• 24 Not started
• 31 Finished

Projects per year

Search results

• Active

  IMPACT ON SURVIVAL OF FAITH-BASED SPIRITUAL CARE OR PSYCHOTHERAPY COMBINED WITH PALLIATIVE CARE VERSUS PALLIATIVE CARE ALONE IN PATIENTS WITH NON-CURATIVE MALIGNANCIES

  Mai, H. P., Abdelrahim, M., Chang, J. C., Ganguly, S., Heyne, K., Mathur, S., Niravath, P. A., Pingali, S. R., Shah, S., Sun, K., Venta, L. A. & Zhang, J.

  6/19/24 → …

  Project: Clinical Trial

• REVIVE: Replens Versus Intra-Vaginal Estrogen for the Treatment of Vaginal Dryness on Aromatase Inhibitor Therapy

  Niravath, P. A., Antosh, D., Chang, J. C., High, R. A., Mai, H. P., Singh, M., Sun, K. & Zaid, T.

  5/17/24 → …

  Project: Clinical Trial

• Breast Cancer Screening & Diagnostics for Black Individuals in the Houston Area (Susan G. Komen)

  Chang, J. C.

  1/1/24 → 12/31/24

  Project: Non Profit

• Dual targeting of PI3K and NOS pathways in Metaplastic Breast Cancer (MBC)

  Chang, J. C.

  7/8/23 → 6/30/28

  Project: Federal Funding Agencies

• Targeting Nitric Oxide Synthase (NOS) pathway to remodel obesity induced tumor inflammation in patients with TNBC

  Chang, J. C.

  12/1/22 → 11/30/24

  Project: State

• A phase II multi-center trial evaluating dual targeting of the PI3K/AKT and NOS pathways for treating metaplastic breast cancer (MpBC)

  Chang, J. C.

  6/10/22 → 5/31/27

  Project: Federal Funding Agencies

• Fulvestrant Plus Abemaciclib With or Without Run-In of Fulvestrant in Er-Positive, Her2-Negative Metastatic Breast Cancer

  Chang, J. C., Mai, H. P., Mathur, S., Niravath, P. A. & Sun, K.

  7/15/21 → …

  Project: Clinical Trial

• Multicenter Phase I/Ib Trial of Olaparib in Combination With Vorinostat in Patients With Relapsed/Refractory and/or Metastatic Breast Cancer

  Chang, J. C., Mai, H. P., Niravath, P. A. & Sun, K.

  2/9/21 → …

  Project: Clinical Trial

• Spatiotemporal modeling of cancer-niche interactions in breast cancer bone metastasis

  Wong, S. T., Chang, J. C. & Sheng, J.

  9/15/20 → 8/31/25

  Project: Federal Funding Agencies

• Convergent AI for Precise Breast Cancer Risk Assessment

  Wong, S. T., Chang, J. C. & Ensor, Jr., J. E.

  6/1/20 → 5/31/25

  Project: Federal Funding Agencies

• Sample and Data Collection for Houston Methodist Cancer Center Research

  Chang, J. C., Bernicker, E. H., Darcourt, J., Heyne, K., Niravath, P. A. & Singh, M.

  4/9/20 → …

  Project: Clinical Trial

• ALLIANCE A221602: OLANZAPINEWITH ORWITHOUT FOSAPREPITANT FOR THE PREVENTION OF CHEMOTHERAPY INDUCED NAUSEA AND VOMITING (CINV) IN PATIENTS RECEIVING HIGHLY EMETOGENIC CHEMOTHERAPY (HEC): A PHASE III RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL

  Darcourt, J., Bernicker, E. H., Chang, J. C., Geyer, C. E., Heyne, K. & Niravath, P. A.

  3/6/20 → 3/5/45

  Project: Non Profit

• CTSU - IRB SUBMISSIONA Phase III Trial To Evaluate The Efficacy Of The Addition Of Inotuzumab Ozogamicin (A Conjugated Anti-Cd22 Monoclonal Antibody) To Frontline Therapy In Young Adults (Ages 18-39 Years) With Newly Diagnosed Precursor B-Cell ALL.

  Abdelrahim, M., Bernicker, E. H., Chang, J. C., Heyne, K., Niravath, P. A., Singh, M. & Zhang, J.

  3/6/20 → 3/5/45

  Project: Non Profit

• Imaging the mechanical microenvironment in cancers using ultrasound

  Chua, C. Y. X. & Chang, J. C.

  3/1/20 → 2/28/25

  Project: Federal Funding Agencies

• Novel potential drug targets for treatment of triple negative breast cancer

  Chang, J. C. & Rosato, R. R.

  10/1/19 → 9/30/25

  Project: Non Profit

• NRG-BR004: A Randomized, Double-Blind, Phase III Trial of Paclitaxel/Trastuzumab/Pertuzumab with Atezolizumab or Placebo in First-Line HER2-Positive Metastatic Breast Cancer

  Geyer, C. E., Niravath, P. A., Chang, J. C. & Darcourt, J.

  3/12/19 → 2/28/25

  Project: Non Profit

• TAILOR RT: A RANDOMIZED TRIAL OF REGIONAL RADIOTHERAPY IN BIOMARKER LOW RISK NODE POSITIVE AND T3N0 BREAST CANCER

  Teh, B. S., Chang, J. C., Farach, A. M., Haque, W. M., Morgan, P. B., Niravath, P. A., Shadle, K. M., Shkedy, C. & Singh, M.

  5/30/18 → 5/29/28

  Project: Non Profit

• A RANDOMIZED PHASE III DOUBLE BLINDED PLACEBO CONTROLLED TRIAL OFASPIRIN AS ADJUVANT THERAPY FOR HER2 NEGATIVE BREAST CANCER: THE ABCTRIAL

  Arentz, C., Abdelrahim, M., Bernicker, E. H., Chang, J. C., Heyne, K., Niravath, P. A., Singh, M. & Zhang, J.

  12/8/16 → 12/7/41

  Project: Non Profit

• EAY131 - Molecular Analysis for Therapy Choice (MATCH)

  Bernicker, E. H., Chang, J. C., Darcourt, J., Heyne, K., Kamat, A. A., Pingali, S. R. & Singh, M.

  9/20/16 → 9/20/41

  Project: Federal Funding Agencies

• Stem Cell: Biomarkers Including Putative Stem Cells Markers in Human Breast Cancers

  Chang, J. C., Heyne, K., Niravath, P. A., Singh, M. & Templeton, S.

  3/20/14 → …

  Project: Clinical Trial

• Metastatic Stem Cells-ROLE OF CANCER STEM CELLS IN BREAST CANCER RECURRENCE AND METASTASIS

  Chang, J. C., Niravath, P. A. & Singh, M.

  3/20/14 → …

  Project: Clinical Trial

• A Randomized Double-Blind Placebo-Controlled Biomarker Modulation Study of Vitamin D in premenopausal Women at High Risk for Breast Cancer, Phase IIB

  Chang, J. C. & Singh, M.

  University of Michigan

  6/29/12 → 3/22/37

  Project: Federal Funding Agencies

• NSABP43; NSABP47; ECOG 2108

  Chang, J. C.

  "NSABP Foundation, Inc"

  3/1/11 → 3/25/26

  Project: Non Profit

• Not started

  Phase II Open Label, Study of IMMU-132 in Metastatic Urothelial Cancer After Failure of Platinum-Based Regimen or Anti-PD-1/ PD-L1 Based Immunotherapy

  Abdelrahim, M., Chang, J. C., Heyne, K., Niravath, P. A. & Singh, M.

  Project: Clinical Trial

• (PENELOPE-B) GBG-78 - BIG 1-13 - NSABP-B-54-I A Study of Palbociclib in Addition to Standard Endocrine Treatment in Hormone Receptor Positive Her2 Normal Patients With Residual Disease After Neoadjuvant Chemotherapy and Surgery

  Chang, J. C., Niravath, P. A. & Singh, M.

  Project: Clinical Trial

• Adipose Tissue and Data Collection from Patients with and without the Diagnosis of Cancer at Houston Methodist Hospital

  Pingali, S. R., Angarita, F. A., Chang, J. C., Esnaola, N. F., Sun, K., Yang, J. & Yi, Q.

  Project: Clinical Trial

• A Pilot Study of Hydroxytyrosol, a Component of Olive Oil for Breast Cancer Prevention In Women At High Risk Of Breast Cancer

  Chang, J. C., Arentz, C., Niravath, P. A., Singh, M. & Templeton, S.

  Project: Clinical Trial

• A Randomized, Double-Blind, Phase III Clinical Trial of Neoadjuvant Chemotherapy With Atezolizumab or Placebo in Patients With Triple-Negative Breast Cancer Followed by Adjuvant Continuation of Atezolizumab or Placebo

  Niravath, P. A., Abdelrahim, M., Arentz, C., Chang, J. C., Heyne, K. & Singh, M.

  Project: Clinical Trial

• Katherine, B50, for Treatment of Adjuvant HER2 Positive Breast Cancer

  Chang, J. C., Niravath, P. A. & Singh, M.

  Project: Clinical Trial

• A Study to Assess the Antitumor Activity and Safety of IMAB362 in Combination With Nab-Paclitaxel and Gemcitabine (Nab-P + GEM) as First Line Treatment in Subjects With Claudin 18.2 (CLDN18.2) Positive, Metastatic Pancreatic Adenocarcinoma

  Abdelrahim, M., Chang, J. C., Heyne, K., Niravath, P. A., Singh, M. & Zhang, J.

  Project: Clinical Trial

• Circulating tumor DNA 5-hydroxymethylcytosine as a novel biomarker for cancers.

  Li, Z., Abdelrahim, M., Chang, J. C., Darcourt, J., Pingali, S. R., Sahay, S., Shah, S., Singh, M., Zhang, J., Zhou, S. & Zu, Y.

  Project: Clinical Trial

• A Randomized Phase III Clinical Trial Evaluating Post-Mastectomy Chestwall and Regional Nodal XRT and Post-Lumpectomy Regional Nodal XRT in Patients With Positive Axillary Nodes Before Neoadjuvant Chemotherapy Who Convert to Pathologically Negative

  Niravath, P. A., Butler, E. B., Chang, J. C., Farach, A. M., Haque, W. M., Heyne, K., Morgan, P. B. & Teh, B. S.

  Project: Clinical Trial

• A Phase 3, Multicenter, Randomized, Open-Label, Active-Controlled Study of Trastuzumab Deruxtecan (T-DXd) Versus Trastuzumab Emtansine (T-DM1) in Participants With High-Risk HER2-Positive Primary Breast Cancer Who Have Residual Invasive Disease in Breast

  Mai, H. P., Chang, J. C., Niravath, P. A., Sun, K. & Templeton, S.

  Project: Clinical Trial

• Emotions, Immunology and Breast Cancer: A Pilot Study

  Venta, L. A. & Chang, J. C.

  Project: Clinical Trial

• BO41843: Phase III_GDC-9545 RO7197597_Breast Cancer_Roche BO41843: A Phase III Randomized, Double-Blind, Placebo-Controlled, Multicenter Study Evaluating the Efficacy and Safety of GDC-9545 Combined With Palbociclib Compared With Letrozole Combined With Palbociclib in Patients With Estrogen Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer

  Niravath, P. A., Chang, J. C., Mai, H. P. & Sun, K.

  Project: Clinical Trial

• Acupuncture Trial

  Niravath, P. A., Chang, J. C., Heyne, K., Mai, H. P., Singh, M. & Sun, K.

  Project: Clinical Trial

• Randomized Study of Erlotinib vs Observation in Patients With Completely Resected Epidermal Growth Factor Receptor (EGFR) Mutant Non-small Cell Lung Cancer (NSCLC)

  Zhang, J., Chang, J. C., Heyne, K., Niravath, P. A. & Singh, M.

  Project: Clinical Trial

• Converting HR Breast Cancer Into an Individualized Vaccine

  Chang, J. C., Mai, H. P., Niravath, P. A. & Sun, K.

  Project: Clinical Trial

• Pivotal, Randomized, Open-label Study of Tumor Treating Fields (TTFields, 150kHz) Concomitant With Gemcitabine and Nab-paclitaxel for Front-line Treatment of Locally-advanced Pancreatic Adenocarcinoma

  Abdelrahim, M., Chang, J. C., Heyne, K., Niravath, P. A., Singh, M. & Templeton, S.

  Project: Clinical Trial

• PALbociclib CoLlaborative Adjuvant Study: A Randomized Phase III Trial of Palbociclib With Standard Adjuvant Endocrine Therapy Versus Standard Adjuvant Endocrine Therapy Alone for Hormone Receptor Positive (HR+) / Human Epidermal Growth Factor Receptor 2

  Niravath, P. A., Chang, J. C. & Singh, M.

  Project: Clinical Trial

• A Randomized, Double-Blind, Phase III Trial of Paclitaxel/Trastuzumab/Pertuzumab With Atezolizumab or Placebo in First-Line HER2-Positive Metastatic Breast Cancer

  Niravath, P. A. & Chang, J. C.

  Project: Clinical Trial

• Docetaxel Chemotherapy and Pembrolizumab Plus Interleukin-12 Gene Therapy in Triple Negative Breast Cancer (INTEGRAL)

  Chang, J. C., Mai, H. P., Niravath, P. A., Sun, K. & Venta, L. A.

  Project: Clinical Trial

• A Prospective Registry Study to Evaluate the Effect of the DCISionRT Test on Treatment Decisions in Patients With DCIS Following Breast Conserving Therapy

  Templeton, S., Arentz, C., Chang, J. C., Darcourt, J., Dubrovsky, E., Haque, W. M., Heyne, K., Morgan, P. B., Niravath, P. A. & Singh, M.

  Project: Clinical Trial

• Multicenter Phase II Trial of Durvalumab (MEDI4736) With Trastuzumab and Pertuzumab Combination in HER2-Enriched and HER2-Amplified Breast Cancer (DTP Trial)

  Chang, J. C., Arentz, C., Mai, H. P., Niravath, P. A. & Sun, K.

  Project: Clinical Trial

• Safety, PK and Efficacy of ONC-392 in Monotherapy and in Combination of Anti-PD-1 in Advanced Solid Tumors and NSCLC (PRESERVE-001)

  Chang, J. C., Mai, H. P., Niravath, P. A. & Sun, K.

  Project: Clinical Trial

• A Study Evaluating the Efficacy and Safety of Adjuvant Giredestrant Compared With Physician's Choice of Adjuvant Endocrine Monotherapy in Participants With Estrogen Receptor-Positive, HER2-Negative Early Breast Cancer (lidERA Breast Cancer)

  Sun, K., Chang, J. C., Mai, H. P., Niravath, P. A. & Templeton, S.

  Project: Clinical Trial

• Brain Metastases Registry

  Rostomily, R. C., Baskin, D. S., Bernicker, E. H., Britz, G. W., Butler, E. B., Chang, J. C., Farach, A. M., Fung, S. H. & Teh, B. S.

  Project: Clinical Trial

• Finished

  Novel potential drug targets for treatment of triple-negative breast cancer

  Chang, J. C.

  10/1/23 → 9/30/24

  Project: Non Profit

• Rationally designed orally delivered small molecules that disable erbB receptors in Breast cancer

  Chang, J. C.

  10/1/22 → 9/30/23

  Project: Federal Funding Agencies

• Contractor shall provide certain breast health screening and diagnostic services

  Chang, J. C.

  4/1/22 → 4/1/24

  Project: Non Profit