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20072022

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Personal profile

Research interests

Dr. Thonhoff’s research focuses on the role of regulatory T cells (Tregs) in ALS. The loss of Treg function is associated with acceleration of disease progression in ALS.  Dr. Thonhoff is exploring the mechanisms through which Treg function is lost in ALS and potential therapies aimed to enhance the neuroprotective function of Tregs. He is also investigating the use of autologous Treg infusions as a therapy for patients with ALS. In addition, he is involved in several clinical trials investigating novel treatments for patients with Myasthenia Gravis, Myotonic Dystrophy and CIDP.

Research Area Keywords

  • Neurosciences
  • Immunobiology & Inflammation

Free-text keywords

  • Neuromuscular disorders
  • Neurodegenerative diseases
  • Amyotrophic Lateral Sclerosis (ALS)
  • Myasthenia Gravis
  • Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
  • Muscular Dystrophy
  • Cellular and genetic therapies
  • Neuroinflammation

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