Projects per year
Personal profile
Personal profile
Dr. Zhao joined the Houston Methodist Research Institute in 2008. She is a member of the American Association for Cancer Research and the International Association for Biological and Medical Research. She has been published in prestigious journals including Science Translational Medicine, Cancer Cell, Cancer Research, et al.
Research interests
Dr. Zhao's research uses systems biology approaches to study and combat brain metastatic cancer. Her projects integrate "dry lab" computational modeling with "wet lab" experimental testing to discover effective treatment strategies and explore personalized drug combinations.
Education/Academic qualification
Biological Sciences, Postdoctoral Fellowship, Harvard University
Molecular Imaging & Systems Biology, Postdoctoral Fellowship, Houston Methodist
Neurology, PhD, Shanghai Medical College of Fudan University
Divisions
- Medical Oncology
Fingerprint
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Sample and Data Collection for Hematologic disorders section, Houston Methodist Cancer Center
Pingali, S. R. (PI), Ganguly, S. (Key Personnel), Heyne, K. (Key Personnel), Hu, C.-C. A. (Key Personnel), Jin, M. M. (Key Personnel), Rice, L. (Key Personnel), Shah, S. (Key Personnel), Yang, J. (Key Personnel), Yi, Q. (Key Personnel), Zhao, H. (Key Personnel) & Zieske, A. W. (Key Personnel)
Project: Clinical Trial
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Systematic identification of astrocyte-tumor crosstalk regulating brain metastatic tumors
Zhao, H. (PI)
2/1/22 → 1/31/25
Project: Federal Funding Agencies
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Systematic identification of astrocyte-tumor crosstalk regulating brain metastatic tumors
Wong, S. T. (PI), Zhao, H. (PI) & Sheng, J. (Key Personnel)
8/1/20 → 1/31/25
Project: Federal Funding Agencies
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Systematic identification of astrocyte-tumor crosstalk regulating brain metastatic tumors
Wong, S. T. (PI), Zhao, H. (PI), Rostomily, R. C. (Key Personnel) & Sheng, J. (Key Personnel)
2/15/20 → 1/31/25
Project: Federal Funding Agencies
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Modeling tumor-stroma crosstalk in lung cancer to identify targets for therapy
Wong, S. T. (PI), Li, F. (Key Personnel) & Zhao, H. (Key Personnel)
7/2/15 → 6/30/20
Project: Federal Funding Agencies
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Artificial Intelligence-Powered Insights into Polyclonality and Tumor Evolution
Zhao, H., Ideker, T. & Wong, S. T. C., 2025, In: Research. 8, 0765.Research output: Contribution to journal › Article › peer-review
Open Access -
GD3 synthase drives resistance to p53-induced apoptosis in breast cancer by modulating mitochondrial function
Anand, V., El-Dana, F., Baran, N., Borgman, J., Yin, Z., Zhao, H., Wong, S. T., Andreeff, M. & Battula, V. L., Aug 11 2025, In: Oncogene. 44, 30, p. 2646-2661 16 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Hydroxytyrosol, a Component of Olive Oil for Breast Cancer Prevention in Women at High Risk of Cancer
Puri, A., Yin, Z., Granados-Principal, S., Ensor, J., Guzman, L., Rosato, R., Zhao, H., Wong, S., Wang, L., Patel, T. & Chang, J. C., 2025, In: International Journal of Breast Cancer. 2025, 1, 8831168.Research output: Contribution to journal › Article › peer-review
Open Access -
Multiscale 3D spatial analysis of the tumor microenvironment using whole-tissue digital histopathology
Kermany, D. S., Ahn, J. Y., Vasquez, M., Zhang, W., Wang, L., Liu, K., Xu, Z., Cho, M. S., Carlos-Alcalde, W., Lee, H., Raghunathan, R., Sheng, J., Hao, X., Zhao, H., Afshar-Kharghan, V., Zhang, X. H. F. & Wong, S. T. C., Mar 2025, In: Cancer Communications. 45, 3, p. 386-390 5 p.Research output: Contribution to journal › Letter › peer-review
Open Access2 Scopus citations -
Quantitative Imaging for Enhanced Thyroid Cancer Diagnosis Using Second Harmonic Generation Microscopy and the Windowed Hough Transform
Poon, W., Davarci, O. O., Raghunathan, R., Liu, J., Zhao, H. & Wong, S. T., 2025, Optica.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
Prizes
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Houston Methodist Cancer Symposium Best Abstract Award
Zhao, H. (Recipient), Aug 12 2016
Prize: Prize (including medals and awards)
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Houston Methodist Cornerstone Award
Zhao, H. (Recipient), Feb 2020
Prize: Prize (including medals and awards)