Projects per year
Personal profile
Personal profile
Dr. Zhao joined the Houston Methodist Research Institute in 2008. She is a member of the American Association for Cancer Research and the International Association for Biological and Medical Research. She has been published in prestigious journals including Science Translational Medicine, Cancer Cell, Cancer Research, et al.
Research interests
Dr. Zhao's research uses systems biology approaches to study and combat brain metastatic cancer. Her projects integrate "dry lab" computational modeling with "wet lab" experimental testing to discover effective treatment strategies and explore personalized drug combinations.
Education/Academic qualification
Biological Sciences, Postdoctoral Fellowship, Brigham and Women’s Hospital, Harvard University, Boston, MA
Neurology, PhD, Shanghai Medical College of Fudan University
Molecular Imaging & Systems Biology, Postdoctoral Fellowship, The Methodist Hospital
Research Area Keywords
- Cancer
Free-text keywords
- Breast cancer
- Brain metastasis
- Systems biology
- Computational modeling
- Imaging
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Network
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Systematic identification of astrocyte-tumor crosstalk regulating brain metastatic tumors
Wong, S. T., Zhao, H. & Sheng, J.
8/1/20 → 1/31/25
Project: Federal Funding Agencies
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Systematic identification of astrocyte-tumor crosstalk regulating brain metastatic tumors
Wong, S. T., Zhao, H., Rostomily, R. C. & Sheng, J.
2/15/20 → 1/31/25
Project: Federal Funding Agencies
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Modeling tumor-stroma crosstalk in lung cancer to identify targets for therapy
Wong, S. T., Li, F. & Zhao, H.
7/2/15 → 6/30/20
Project: Federal Funding Agencies
Research output
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64Cu/177Lu-DOTA-diZD, a Small-Molecule-Based Theranostic Pair for Triple-Negative Breast Cancer
Huang, Y., Yang, Z., Li, F., Zhao, H., Li, C., Yu, N., Hamilton, D. J. & Li, Z., Mar 11 2021, In: Journal of Medicinal Chemistry. 64, 5, p. 2705-2713 9 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Artificial intelligence-augmented, label-free molecular imaging method for tissue identification, cancer diagnosis, and cancer margin detection
Li, J., Liu, J., Wang, Y., He, Y., Liu, K., Raghunathan, R., Shen, S. S., He, T., Yu, X., Danforth, R., Zheng, F., Zhao, H. & Wong, S. T. C., Sep 1 2021, In: Biomedical Optics Express. 12, 9, p. 5559-5582 24 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Deep learning powers cancer diagnosis in digital pathology
He, Y., Zhao, H. & Wong, S. T. C., Mar 2021, In: Computerized Medical Imaging and Graphics. 88, 101820.Research output: Contribution to journal › Review article › peer-review
3 Scopus citations -
Novel STAT3 small-molecule inhibitors identified by structure-based virtual ligand screening incorporating SH2 domain flexibility
Kong, R., Bharadwaj, U., Eckols, T. K., Kolosov, M., Wu, H., Cruz-Pavlovich, F. J. S., Shaw, A., Ifelayo, O. I., Zhao, H., Kasembeli, M. M., Wong, S. T. C. & Tweardy, D. J., Jul 2021, In: Pharmacological Research. 169, 105637.Research output: Contribution to journal › Article › peer-review
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The Progress of Label-Free Optical Imaging in Alzheimer’s Disease Screening and Diagnosis
Liu, K., Li, J., Raghunathan, R., Zhao, H., Li, X. & Wong, S. T. C., Jul 22 2021, In: Frontiers in Aging Neuroscience. 13, 699024.Research output: Contribution to journal › Review article › peer-review
Open Access
Prizes
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Houston Methodist Cancer Symposium Best Abstract Award
Zhao, Hong (Recipient), Aug 12 2016
Prize: Prize (including medals and awards)
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Houston Methodist Cornerstone Award
Zhao, Hong (Recipient), Feb 2020
Prize: Prize (including medals and awards)