Research outputs

  1. 2019
  2. MAP4K4 Inhibition Promotes Survival of Human Stem Cell-Derived Cardiomyocytes and Reduces Infarct Size In Vivo

    Fiedler, L. R., Chapman, K., Xie, M., Maifoshie, E., Jenkins, M., Golforoush, P. A., Bellahcene, M., Noseda, M., Faust, D., Jarvis, A., Newton, G., Paiva, M. A., Harada, M., Stuckey, D. J., Song, W., Habib, J., Narasimham, P., Aqil, R., Sanmugalingam, D., Yan, R. & 14 othersPavanello, L., Sano, M., Wang, S. C., Sampson, R. D., Kanayaganam, S., Taffet, G., Michael, L. H., Entman, M. L., Tan, T. H., Harding, S. E., Low, C. M. R., Tralau-Stewart, C., Perrior, T. & Schneider, M. D., Apr 4 2019, In : Cell Stem Cell. 24, 4, p. 579-591.e12

    Research output: Contribution to journalArticle

  3. Postnatal undernutrition alters adult female mouse cardiac structure and function leading to limited exercise capacity

    Ferguson, D. P., Monroe, T. O., Heredia, C. P., Fleischmann, R., Rodney, G. G., Taffet, G. & Fiorotto, M. L., Jan 1 2019, In : Journal of Physiology.

    Research output: Contribution to journalArticle

  4. 2018
  5. Improved Cardiovascular Function in Old Mice After N-Acetyl Cysteine and Glycine Supplemented Diet: Inflammation and Mitochondrial Factors

    Cieslik, K. A., Sekhar, R. V., Granillo, A., Reddy, A., Medrano, G., Heredia, C. P., Entman, M. L., Hamilton, D. J., Li, S., Reineke, E., Gupte, A. A., Zhang, A. & Taffet, G. E., Aug 10 2018, In : The journals of gerontology. Series A, Biological sciences and medical sciences. 73, 9, p. 1167-1177 11 p.

    Research output: Contribution to journalArticle

  6. Multicomponent Interventions Reduce High-Risk Medications for Delirium in Hospitalized Older Adults

    Adeola, M., Azad, R., Kassie, G. M., Shirkey, B., Taffet, G., Liebl, M. & Agarwal, K., Aug 1 2018, In : Journal of the American Geriatrics Society. 66, 8, p. 1638-1645 8 p.

    Research output: Contribution to journalArticle

  7. Transient activation of AMPK preceding left ventricular pressure overload reduces adverse remodeling and preserves left ventricular function

    Nam, D. H., Kim, E., Benham, A., Park, H-K., Soibam, B., Taffet, G. E., Kaelber, J. T., Suh, J. H., Taegtmeyer, H., Entman, M. L. & Reineke, E. L., Jul 19 2018, In : FASEB journal : official publication of the Federation of American Societies for Experimental Biology. p. fj201800602R

    Research output: Contribution to journalArticle

  8. Short-Term Global Cardiovascular Disease Risk Prediction in Older Adults

    Saeed, A., Nambi, V., Sun, W., Virani, S. S., Taffet, G., Deswal, A., Selvin, E., Matsushita, K., Wagenknecht, L. E., Hoogeveen, R., Coresh, J., de Lemos, J. A. & Ballantyne, C. M., Jun 5 2018, In : Journal of the American College of Cardiology. 71, 22, p. 2527-2536 10 p.

    Research output: Contribution to journalArticle

  9. Improved cardiovascular function in old mice after N-Acetyl cysteine and glycine supplemented diet: Inflammation and mitochondrial factors

    Cieslik, K. A., Sekhar, R. V., Granillo, A., Reddy, A., Medrano, G., Heredia, C. P., Entman, M. L., Hamilton, D. J., Li, S., Reineke, E. L., Gupte, A. A., Zhang, A. & Taffet, G., Jan 1 2018, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 73, 9, p. 1167-1177 11 p.

    Research output: Contribution to journalArticle

  10. Prevalence of Cognitive Impairment Among Elderly Patients Upon Hospital Admission Using Mini-Cog™ Assessments Performed by Advanced Pharmacy Practice Experience Students

    Bui, N. A., Adeola, M., Azad, R., Swan, J. T., Agarwal, K. S., Sharma, M., Liebl, M. G. & Taffet, G., 2018, (Accepted/In press) In : Journal of Pharmacy Practice.

    Research output: Contribution to journalArticle

  11. 2017
  12. Cardiac Resynchronization Therapy in Older Adults with Heart Failure

    Lam, P. H., Taffet, G., Ahmed, A. & Singh, S., Jul 1 2017, In : Heart Failure Clinics. 13, 3, p. 581-587 7 p.

    Research output: Contribution to journalReview article

  13. Dissecting the role of myeloid and mesenchymal fibroblasts in age-dependent cardiac fibrosis

    Trial, J. A., Heredia, C. P., Taffet, G. E., Entman, M. L. & Cieslik, K. A., Jul 1 2017, In : Basic Research in Cardiology. 112, 4, 34.

    Research output: Contribution to journalArticle

  14. Murine echocardiography of left atrium, aorta, and pulmonary artery

    Granillo, A., Pena, C. A., Pham, T., Pandit, L. M. & Taffet, G., Feb 20 2017, In : Journal of Visualized Experiments. 2017, 120, e55214.

    Research output: Contribution to journalArticle

  15. Hospital and physician rating websites: Ethical challenges without context

    Taffet, G., Jan 31 2017, Ethical Considerations and Challenges in Geriatrics. Springer International Publishing, p. 137-145 9 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  16. Steroid receptor coactivator-2 (SRC-2) coordinates cardiomyocyte paracrine signaling to promote pressure overload-induced angiogenesis

    Suh, J. H., Lai, L., Nam, D., Kim, J., Jo, J., Taffet, G. E., Kim, E., Kaelber, J. T., Lee, H. K., Entman, M. L., Cooke, J. P. & Reineke, E. L., 2017, In : Journal of Biological Chemistry. 292, 52, p. 21643-21652 10 p.

    Research output: Contribution to journalArticle

  17. 2016
  18. Unrecognized Cognitive Impairment and Its Effect on Heart Failure Readmissions of Elderly Adults

    Agarwal, K. S., Kazim, R., Xu, S., Borson, S. & Taffet, G., Nov 1 2016, In : Journal of the American Geriatrics Society. 64, 11, p. 2296-2301 6 p.

    Research output: Contribution to journalArticle

  19. Left atrial volume and pulmonary artery diameter are noninvasive measures of age-related diastolic dysfunction in mice

    Medrano, G., Hermosillo-Rodriguez, J., Pham, T., Granillo, A., Hartley, C. J., Reddy, A., Osuna, P. M., Entman, M. L. & Taffet, G., Sep 1 2016, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 71, 9, p. 1141-1150 10 p.

    Research output: Contribution to journalArticle

  20. Measures of healthspan as indices of aging in Mice-A recommendation

    Richardson, A., Fischer, K. E., Speakman, J. R., De Cabo, R., Mitchell, S. J., Peterson, C. A., Rabinovitch, P., Chiao, Y. A., Taffet, G., Miller, R. A., Rentería, R. C., Bower, J., Ingram, D. K., Ladiges, W. C., Ikeno, Y., Sierra, F. & Austad, S. N., Apr 1 2016, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 71, 4, p. 427-430 4 p.

    Research output: Contribution to journalArticle

  21. TNF/Ang-II synergy is obligate for fibroinflammatory pathology, but not for changes in cardiorenal function

    Mayr, M., Duerrschmid, C., Medrano, G., Taffet, G., Wang, Y., Entman, M. L. & Haudek, S. B., Apr 1 2016, In : Physiological Reports. 4, 8, e12765.

    Research output: Contribution to journalArticle

  22. Plasma Levels of Endothelial Microparticles Bearing Monomeric C-reactive Protein are Increased in Peripheral Artery Disease

    Crawford, J. R., Trial, J., Nambi, V., Hoogeveen, R. C., Taffet, G. & Entman, M. L., Feb 18 2016, (Accepted/In press) In : Journal of Cardiovascular Translational Research. p. 1-10 10 p.

    Research output: Contribution to journalArticle

  23. Prognostic significance of anaemia in patients with heart failure with preserved and reduced ejection fraction: Results from the MAGGIC individual patient data meta-analysis

    Berry, C., Poppe, K. K., Gamble, G. D., Earle, N. J., Ezekowitz, J. A., Squire, I. B., McMurray, J. J. V., McAlister, F. A., Komajda, M., Swedberg, K., Maggioni, A. P., Ahmed, A., Whalley, G. A., Doughty, R. N., Tarantini, L., Granger, C., Køber, L., Massie, B., Pocock, S., Somaratne, J. & 147 othersAndersson, B., Bayes-Genis, A., Cowie, M., Cubbon, R., Gonzalez-Juanatey, J., Gorini, M., Gotsman, I., Grigorian-Shamagian, L., Guazzi, M., Kearney, M., Di Lenarda, A., Lenzen, M., Lucci, D., Macín, S., Madsen, B., Martínez-Sellés, M., Oliva, F., Rich, M., Richards, M., Senni, M., Taffet, G., Tribouilloy, C., Troughton, R., Tsutsui, H., Ariti, C., Dobson, J., Hall, C., Lainchbury, J., Hogg, K., Norrie, J., Stevenson, K., Brett, M., Pfeffer, M. A., Held, P., Michelson, E. L., Olofsson, B., Östergren, J., Yusuf, S., Torp-Pedersen, C., Scholte op Reimer, W., Boersma, E., Vantrimpont, P. J. M. J., Follath, F., Cleland, J., Zwas, D., Planer, D., Azaz-Livshits, T., Admon, D., Lotan, C., Keren, A., Varela-Roman, A., Mazón-Ramos, P., Rigeiro-Veloso, P., Bandin-Dieguez, M. A., Myers, J., Arena, R., Armstrong, P. W., Cujec, B., Paterson, I., Wood, D. A., Coats, A. J. S., Thompson, S. G., Suresh, V., Poole-Wilson, P. A., Sutton, G. C., Robles, J. A. G., Prieto, L., Muñoa, M. D., Frades, E., Díaz-Castro, O., Almendral, J., Faggiano, P., Bertoli, D., Porcu, M., Opasich, C., Tavazzi, L., Kirk, V., Bay, M., Parner, J., Krogsgaard, K., Herzog, T. M., Boesgaard, S., Hassager, C., Nielsen, O. W., Aldershvile, J., Nielsen, H., Kober, L., Perna, E. R., Cimbaro Canella, J. P., Alvarenga, P., Pantich, R., Ríos, N., Farias, E. F., Badaracco, J. R., Hansen, J. F., Stokholm, K. H., Brons, J., Husum, D., Mortensen, L. S., Vazquez, R., Puig, T., Fernandez-Palomeque, C., Bardají, A., Pascual-Figal, D., Ordoñez-Llanos, J., Valdes, M., Gabarrus, A., Pavon, R., Pastor, L., Fiol, M., Nieto, V., Macaya, C., Cinca, J., Cygankiewitz, I., Bayes De Luna, A., Newton, J. D., Blackledge, H. M., Wright, S. P., Kerzner, R., Gage, B. F., Freedland, K. E., Huynh, B. C., Rovner, A., Carney, R. M., Teasdale, T. A., Bleyer, A. J., Kutka, N. J., Luchi, R. J., Rusinaru, D., Mahjoub, H., Soulière, V., Lévy, F., Peltier, M., Tsuchihashi, M., Takeshita, A., MacCarthy, P. A., Nolan, J., Lee, A. J., Prescott, R. J., Shah, A. M., Brooksby, W. P., Fox, K. A. A., Basante, P., Trillo, R., Garcia-Seara, J., Martinez-Sande, J. L. & Gude, F., 2016, In : QJM. 109, 6, p. 377-382 6 p.

    Research output: Contribution to journalArticle

  24. 2015
  25. PHD2/3-dependent hydroxylation tunes cardiac response to β-adrenergic stress via phospholamban

    Xie, L., Pi, X., Townley-Tilson, W. H. D., Li, N., Wehrens, X. H. T., Entman, M. L., Taffet, G. E., Mishra, A., Peng, J., Schisler, J. C., Meissner, G. & Patterson, C., Jul 1 2015, In : Journal of Clinical Investigation. 125, 7, p. 2759-2771 13 p.

    Research output: Contribution to journalArticle

  26. Heart failure with preserved ejection fraction in the elderly: Scope of the problem

    Upadhya, B., Taffet, G., Cheng, C. P. & Kitzman, D. W., Jun 1 2015, In : Journal of Molecular and Cellular Cardiology. 83, p. 73-87 15 p.

    Research output: Contribution to journalArticle

  27. High-Sensitivity troponin t and cardiovascular events in systolic blood pressure categories atherosclerosis risk in communities study

    Pokharel, Y., Sun, W., De Lemos, J. A., Taffet, G. E., Virani, S. S., Ndumele, C. E., Mosley, T. H., Hoogeveen, R. C., Coresh, J., Wright, J. D., Heiss, G., Boerwinkle, E. A., Bozkurt, B., Solomon, S. D., Ballantyne, C. M. & Nambi, V., Jan 1 2015, In : Hypertension. 65, 1, p. 78-84 7 p.

    Research output: Contribution to journalArticle

  28. Cardiovascular physiology in the older adults

    Dai, X., Hummel, S. L., Salazar, J. B., Taffet, G., Zieman, S. & Schwartz, J. B., 2015, In : Journal of Geriatric Cardiology. 12, 3, p. 196-201 6 p.

    Research output: Contribution to journalArticle

  29. Substance P receptor antagonism: A potential novel treatment option for viral-myocarditis

    Robinson, P., Taffet, G., Engineer, N., Khumbatta, M., Firozgary, B., Reynolds, C., Pham, T., Bulsara, T. & Firozgary, G., 2015, In : BioMed Research International. 2015, 645153.

    Research output: Contribution to journalArticle

  30. 2014
  31. Hypernatremia in the geriatric population

    Shah, M. K., Workeneh, B. & Taffet, G., Nov 19 2014, In : Clinical Interventions in Aging. 9, p. 1987-1992 6 p.

    Research output: Contribution to journalArticle

  32. Vascular and parenchymal amyloid pathology in an Alzheimer disease knock-in mouse model: Interplay with cerebral blood flow

    Li, H., Guo, Q., Inoue, T., Polito, V. A., Tabuchi, K., Hammer, R. E., Pautler, R. G., Taffet, G. & Zheng, H., Aug 9 2014, In : Molecular Neurodegeneration. 9, 1, 28.

    Research output: Contribution to journalArticle

  33. Young Little mice express a premature cardiovascular aging phenotype

    Reddy, A. K., Hartley, C. J., Pham, T. T., Darlington, G., Entman, M. L. & Taffet, G., Mar 17 2014, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 69 A, 2, p. 152-159 8 p.

    Research output: Contribution to journalArticle

  34. Adverse fibrosis in the aging heart depends on signaling between myeloid and mesenchymal cells; role of inflammatory fibroblasts

    Cieslik, K. A., Trial, J., Crawford, J. R., Taffet, G. & Entman, M. L., Jan 1 2014, In : Journal of Molecular and Cellular Cardiology. 70, p. 56-63 8 p.

    Research output: Contribution to journalArticle

  35. 2013
  36. The survival of patients with heart failure with preserved or reduced left ventricular ejection fraction: An individual patient data meta-analysis: Meta-analysis Global Group in Chronic Heart Failure (MAGGIC)

    Meta-analysis Global Group in Chronic Heart Failure (MAGGIC), Dec 20 2013, In : European Heart Journal. 33, 14, p. 1750-1757 8 p.

    Research output: Contribution to journalArticle

  37. Considerations for managing chronic obstructive pulmonary disease in the elderly

    Taffet, G., Donohue, J. F. & Altman, P. R., Dec 13 2013, In : Clinical Interventions in Aging. 9, p. 23-30 8 p.

    Research output: Contribution to journalArticle

  38. AICAR-dependent AMPK activation improves scar formation in the aged heart in a murine model of reperfused myocardial infarction

    Cieslik, K. A., Taffet, G., Crawford, J. R., Trial, J., Mejia Osuna, P. & Entman, M. L., Oct 1 2013, In : Journal of Molecular and Cellular Cardiology. 63, p. 26-36 11 p.

    Research output: Contribution to journalArticle

  39. microRNA-22 Promotes Heart Failure through Coordinate Suppression of PPAR/ERR-Nuclear Hormone Receptor Transcription

    Gurha, P., Wang, T., Larimore, A. H., Sassi, Y., Abreu-Goodger, C., Ramirez, M. O., Reddy, A. K., Engelhardt, S., Taffet, G., Wehrens, X. H. T., Entman, M. L. & Rodriguez, A., Sep 27 2013, In : PLoS ONE. 8, 9, e75882.

    Research output: Contribution to journalArticle

  40. Application of speckle-tracking in the evaluation of carotid artery function in subjects with hypertension and diabetes

    Yang, E. Y., Brunner, G., Dokainish, H., Hartley, C. J., Taffet, G., Lakkis, N., Taylor, A. A., Misra, A., McCulloch, M. L., Morrisett, J. D., Virani, S. S., Ballantyne, C. M., Nagueh, S. & Nambi, V., Aug 1 2013, In : Journal of the American Society of Echocardiography. 26, 8

    Research output: Contribution to journalArticle

  41. Incidence of cholinesterase inhibitor therapy initiation among hospitalized patients

    Swan, J. T., Wagle, K. C., Thompson-Moore, N. & Taffet, G., Jun 1 2013, In : Journal of Hospital Medicine. 8, 6, p. 304-308 5 p.

    Research output: Contribution to journalArticle

  42. Initiation of cholinesterase inhibitors in an inpatient setting

    Wagle, K. C., Rowan, P. J., Poon, O. Y. I., Kunik, M. E., Taffet, G. & Braun, U. K., Jun 1 2013, In : American Journal of Alzheimer's Disease and other Dementias. 28, 4, p. 377-383 7 p.

    Research output: Contribution to journalArticle

  43. Aberrant differentiation of fibroblast progenitors contributes to fibrosis in the aged murine heart: Role of elevated circulating insulin levels

    Cieslik, K. A., Trial, J., Carlson, S., Taffet, G. & Entman, M. L., Apr 1 2013, In : FASEB Journal. 27, 4, p. 1761-1771 11 p.

    Research output: Contribution to journalArticle

  44. TNF receptor 1 signaling is critically involved in mediating angiotensin-II-induced cardiac fibrosis

    Duerrschmid, C., Crawford, J. R., Reineke, E. L., Taffet, G., Trial, J., Entman, M. L. & Haudek, S. B., Apr 1 2013, In : Journal of Molecular and Cellular Cardiology. 57, 1, p. 59-67 9 p.

    Research output: Contribution to journalArticle

  45. 2012
  46. SRC-2 Coactivator Deficiency Decreases Functional Reserve in Response to Pressure Overload of Mouse Heart

    Reineke, E. L., York, B., Stashi, E., Chen, X., Tsimelzon, A., Xu, J., Newgard, C. B., Taffet, G. E., Taegtmeyer, H., Entman, M. L. & O'Malley, B. W., Dec 31 2012, In : PLoS ONE. 7, 12, e53395.

    Research output: Contribution to journalArticle

  47. The Cardiovascular System

    Michael, L. H., Taffet, G., Entman, M. L., Reddy, A. K., Hartley, C. J. & Frangogiannis, N. G., Dec 1 2012, The Laboratory Mouse. Elsevier, p. 241-270 30 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  48. An Educational Program to Assist Clinicians in Identifying Elder Investment Fraud and Financial Exploitation

    Mills, W. L., Roush, R. E., Moye, J., Kunik, M. E., Wilson, N. L., Taffet, G. & Naik, A. D., Oct 1 2012, In : Gerontology and Geriatrics Education. 33, 4, p. 351-363 13 p.

    Research output: Contribution to journalArticle

  49. An online spaced-education game to teach and assess medical students: A multi-institutional prospective trial

    Kerfoot, B. P., Baker, H., Pangaro, L., Agarwal, K., Taffet, G., Mechaber, A. J. & Armstrong, E. G., Oct 1 2012, In : Academic Medicine. 87, 10, p. 1443-1449 7 p.

    Research output: Contribution to journalArticle

  50. Why clinicians need to know about the elder investment fraud and financial exploitation program

    Roush, R. E., Moye, J. A., Mills, W. L., Kunik, M. E., Wilson, N. L., Taffet, G. & Naik, A. D., Jul 1 2012, In : Generations. 36, 2, p. 94-97 4 p.

    Research output: Contribution to journalArticle

  51. Targeted deletion of MicroRNA-22 promotes stress-induced cardiac dilation and contractile dysfunction

    Gurha, P., Abreu-Goodger, C., Wang, T., Ramirez, M. O., Drumond, A. L., Van Dongen, S., Chen, Y., Bartonicek, N., Enright, A. J., Lee, B., Kelm, R. J., Reddy, A. K., Taffet, G., Bradley, A., Wehrens, X. H., Entman, M. L. & Rodriguez, A., Jun 5 2012, In : Circulation. 125, 22, p. 2751-2761 11 p.

    Research output: Contribution to journalArticle

  52. 2011
  53. Cholinesterase inhibitor initiation in hospital setting

    Wagle, K. C., Natali, B. & Taffet, G., Oct 1 2011, In : Journal of the American Geriatrics Society. 59, 10, p. 1988-1989 2 p.

    Research output: Contribution to journalArticle

  54. Disruption of K2P6.1 produces vascular dysfunction and hypertension in mice

    Lloyd, E. E., Crossland, R. F., Phillips, S. C., Marrelli, S. P., Reddy, A. K., Taffet, G., Hartley, C. J. & Bryan, R. M., Oct 1 2011, In : Hypertension. 58, 4, p. 672-678 7 p.

    Research output: Contribution to journalArticle

  55. Deficient synthesis of glutathione underlies oxidative stress in aging and can be corrected by dietary cysteine and glycine supplementation

    Sekhar, R. V., Patel, S. G., Guthikonda, A. P., Reid, M., Balasubramanyam, A., Taffet, G. & Jahoor, F., Sep 1 2011, In : American Journal of Clinical Nutrition. 94, 3, p. 847-853 7 p.

    Research output: Contribution to journalArticle

  56. CCR2 mediates the uptake of bone marrow-derived fibroblast precursors in angiotensin II-induced cardiac fibrosis

    Xu, J., Lin, S. C., Chen, J., Miao, Y., Taffet, G., Entman, M. L. & Wang, Y., Aug 1 2011, In : American Journal of Physiology - Heart and Circulatory Physiology. 301, 2

    Research output: Contribution to journalArticle

  57. Doppler velocity measurements from large and small arteries of mice

    Hartley, C. J., Reddy, A. K., Madala, S., Entman, M. L., Michael, L. H. & Taffet, G., Aug 1 2011, In : American Journal of Physiology - Heart and Circulatory Physiology. 301, 2

    Research output: Contribution to journalArticle

  58. Novel approaches to perioperative assessment and intervention may improve long-term outcomes after colorectal cancer resection in older adults

    Cheema, F. N., Abraham, N. S., Berger, D. H., Albo, D., Taffet, G. E. & Naik, A. D., May 1 2011, In : Annals of Surgery. 253, 5, p. 867-874 8 p.

    Research output: Contribution to journalArticle

  59. Immune-inflammatory dysregulation modulates the incidence of progressive fibrosis and diastolic stiffness in the aging heart

    Cieslik, K. A., Taffet, G., Carlson, S., Hermosillo, J., Trial, J. & Entman, M. L., Jan 1 2011, In : Journal of Molecular and Cellular Cardiology. 50, 1, p. 248-256 9 p.

    Research output: Contribution to journalArticle

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