Projects per year
Personal profile
Research interests
Dr. Leonard’s research focuses on nanomedicine design for polymeric and lipid nanoparticle platforms. She is particularly interested in macrophage modulation via in vivo targeted CRISPR editing in various inflammatory conditions such as atherosclerosis, inflammatory bowel disease, and cancer. She has also developed several disease‐specific 3D in vitro models for drug screening and assessing treatment efficacy metrics
Education/Academic qualification
ME, Technical University of Berlin
PhD, Universität des Saarlandes
Research Area Keywords
- Nanomedicine
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Collaborations and top research areas from the last five years
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Projects
- 2 Finished
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Evaluation of immune responses to CD44-targeted nanovectors for designing a novel anti-tuberculosis host-directed therapy
Godin, B. (PI), Jagannath, C. (PI) & Leonard, F. (Key Personnel)
5/1/20 → 10/31/22
Project: Federal Funding Agencies
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CRISPR-nanoparticle for macrophage reprogramming: New therapeutic strategy for breast cancer liver metastasis
Leonard, F. (PI)
4/1/19 → 3/10/21
Project: Non Profit
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A parametric study of motion and attachment to capillary walls of circulating tumor cells (CTCs) interacting with non-activated and activated platelets
Simic, V., Nikolic, A., Ning, S., Milosevic, M., Leonard, F., Liu, X. & Kojic, M., Jun 2025, In: Computer Methods and Programs in Biomedicine. 264, 108699.Research output: Contribution to journal › Article › peer-review
Open Access -
Modeling critical interaction for metastasis between circulating tumor cells (CTCs) and platelets adhered to the capillary wall
Milosevic, M., Simic, V., Nikolic, A., Shao, N., Kawamura Hashimoto, C., Godin, B., Leonard, F., Liu, X. & Kojic, M., Dec 1 2023, In: Computer Methods and Programs in Biomedicine. 242, 107810.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
Heat-induced SIRT1-mediated H4K16ac deacetylation impairs resection and SMARCAD1 recruitment to double strand breaks
Chakraborty, S., Singh, M., Pandita, R. K., Singh, V., Lo, C. S. C., Leonard, F., Horikoshi, N., Moros, E. G., Guha, D., Hunt, C. R., Chau, E., Ahmed, K. M., Sethi, P., Charaka, V., Godin, B., Makhijani, K., Scherthan, H., Deck, J., Hausmann, M. & Mushtaq, A. & 6 others, , Apr 15 2022, In: iScience. 25, 4, p. 104142 104142.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Design and in vitro characterization of multistage silicon-PLGA budesonide particles for inflammatory bowel disease
Leonard, F., Srinivasan, S., Liu, X., Collnot, E. M., Ferrari, M., Lehr, C. M. & Godin, B., Jun 1 2020, In: European Journal of Pharmaceutics and Biopharmaceutics. 151, p. 61-72 12 p.Research output: Contribution to journal › Article › peer-review
18 Scopus citations -
Immunotherapeutics for head and neck squamous cell carcinoma stem cells
Qian, X., Leonard, F., Wenhao, Y., Sudhoff, H., Hoffmann, T. K., Ferrone, S., Kaufmann, A. M. & Albers, A. E., Feb 1 2020, In: HNO. 68, 2, p. 94-99 6 p.Research output: Contribution to journal › Review article › peer-review
6 Scopus citations