Projects per year
Personal profile
Personal profile
Dr. Taraballi earned her B.S. in Biological Sciences and her M.S. in Biochemistry at University of Milan – Bicocca, Italy. After another M.S. in Structural Biochemistry, she earned her Ph.D. in Nanostructures and Nanotechnologies from a joint program of the Materials Science Department of University of Milan, Bicocca with the Lawrence National Berkeley Laboratory.
Dr. Taraballi is currently an Assistant Professor and serves as Director of the Center for Musculoskeletal Regeneration at Houston Methodist Research Institute affiliated to the Department of Orthopedics and Sports Medicine at Houston Methodist Hospital. At the same time, Dr. Taraballi is also affiliated faculty to the Center for RNA therapeutics, the Department of Nanomedicine and the Neal Cancer Center of Houston Methodist Academic Institute.
Dr. Taraballi’s research is focused on the development of smart biomaterials, both injectable and implantable, to target the immune system toward tissue restoration. Dr. Taraballi’s contributions to the field of nanomedicine are truly extraordinary. Her research paved the way for novel drug delivery platforms capable of precise targeting, enhancing drug efficacy while minimizing side effects. Her innovative work has shown great promise in treating various diseases, including cancer, neurological disorders, and orthopedic conditions. Throughout her career, Dr. Taraballi has been a strong advocate for education and mentorship. She actively participates in mentoring young scientists and students, inspiring the next generation to pursue careers in STEM fields. Her dedication to fostering scientific curiosity has left a lasting impact on many aspiring researchers. Dr. Taraballi’s success can be attributed not only to her resources but also to her unwavering commitment to making the world a better place. Her belief in the power of interdisciplinary collaboration and her willingness to embrace challenges have propelled her forward in her journey of scientific exploration and innovation.
Research interests
- mRNA therapeutics for orthopedic applications
- mRNA vaccine development and validation in small and large animal models.
- Translational bioaterials fabrication and functionalization to tune the immune system towards tissue homeostasis for reconstructive surgery
- cGMP fabrication of devices and regulatory studies for validation
- Development of smart nano-biomaterials to tune the immune system
- Enhancing immunemodulatories capabilities of mesenchymal stem cells from different sources for surgical adjiuvant. (Clinical trials)
- Evaluation of local delivery of antibiotics to fight surgical-related infections (Clinial trials)
Research Area Keywords
- Nanomedicine
- Orthopedics & Sports Medicine
- Infectious Disease & Pathology
- Immunobiology & Inflammation
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- 6 Similar Profiles
Collaborations and top research areas from the last five years
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Biomimetic Nanoparticles-Mediated Delivery of Immunomodulating Nucleic Acids as a Strategy to Anticipate Melanoma Drug Resistance
Taraballi, F. (PI)
9/1/23 → 8/31/26
Project: Federal Funding Agencies
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A Local Immunoactive Patch for the Treatment of Chronic Wounds
Taraballi, F. (PI)
1/15/23 → 1/14/26
Project: Federal Funding Agencies
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Intraosseous vs. Intravenous Vancomycin Administration in Total Shoulder Arthroplasty: Changing the Paradigm
McCulloch, P. (PI), Park, K. (Key Personnel) & Taraballi, F. (Key Personnel)
Project: Clinical Trial
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PROTEOMICS BASED MAPPING OF CARDIAC EXTRACELLULAR MATRIX TO DEFINE SEX AND AGE-DEPENDENT CHANGES
Taraballi, F. (PI)
8/1/23 → 4/30/24
Project: Federal Funding Agencies
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CXCL9 as an immune anti-melanoma therapy in combination with BRAF inhibition
Taraballi, F. (PI)
1/1/21 → 12/31/22
Project: Non Profit
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Advantages of nanoencapsulation in the delivery of therapeutics for bone regeneration
Banche-Niclot, F. & Taraballi, F., 2025, (Accepted/In press) In: Nanomedicine.Research output: Contribution to journal › Editorial › peer-review
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RNA therapies for musculoskeletal conditions
Mancino, C., Franke, M., Greco, A., Sontam, T., Mcculloch, P., Corbo, C. & Taraballi, F., Jan 10 2025, In: Journal of Controlled Release. 377, p. 756-766 11 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
1034 Development of HLA class I expressing humanized patient-derived xenograft (hu-PDX) mouse models for the study of mRNA-based cancer vaccines in triple-negative breast cancer
Chervo, M. F., Qian, W., Ortega Martinez, K. A., Zhou, J., Shroff, R., Mancino, C., Rojas, L. G., Taraballi, F., Cooke, J. P., Gollihar, J. D. & Chang, J. C., Nov 1 2024, In: J Immunother Cancer. 12, Suppl 2, p. A1155Research output: Contribution to journal › Article › peer-review
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Adipocyte derived exosomes promote cell invasion and challenge paclitaxel efficacy in ovarian cancer
Williams, M. E., Howard, D., Donnelly, C., Izadi, F., Parra, J. G., Pugh, M., Edwards, K., Lutchman-Sigh, K., Jones, S., Margarit, L., Francis, L., Conlan, R. S., Taraballi, F. & Gonzalez, D., Sep 16 2024, In: Cell Communication and Signaling. 22, 1, 443.Research output: Contribution to journal › Article › peer-review
Open Access -
Electrospun Chitosan-Based Nanofibrous Coating for the Local and Sustained Release of Vancomycin
Serpelloni, S., Williams, M. E., Caserta, S., Sharma, S., Rahimi, M. & Taraballi, F., Mar 12 2024, In: ACS Omega. 9, 10, p. 11701-11717 17 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations
Prizes
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EnMed Mentorship award
Taraballi, F. (Recipient), Aug 12 2022
Prize: Prize (including medals and awards)
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ON-ICRS Research Fellowship 2018
Taraballi, F. (Recipient), 2018
Prize: Fellowship awarded competitively