Projects per year
Personal profile
Personal profile
Dr. Eugene C. Lai is a clinician-scientist who has a special interest in the causes and treatments of neurodegenerative diseases, such as Parkinson’s disease, Alzheimer’s disease, amyotrophic lateral sclerosis, and other related disorders. Dr. Lai has expertise in the assessment of motor function and quality of life. He is the principal investigator or co-investigator of many clinical research studies. His work has appeared in more than one hundred scientific publications and book chapters, and has lectured widely on topics in neurodegenerative diseases.
Research interests
Dr. Lai's research interests are in the causes and treatments of neurodegenerative diseases and the assessment of motor function and quality of life of patients with movement disorders and dementias.
Education/Academic qualification
MD, Baylor College of Medicine
May 1 1990 → Jun 1 1994
Award Date: Jun 1 1994
Baylor College of Medicine
Research Area Keywords
- Neurosciences
- Systems Medicine & Bioinformatics
- Clinical Translation & Trials
Free-text keywords
- Neurodegenerative disease
- Motor function assessment
- Movement disorders
- Dementia
- Quality of life
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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A Study of Biological Markers for the Nervous and Immune Systems and Free Radical Mediated Processes in Amyotrophic Lateral Sclerosis (ALS)
Appel, S. H. (PI), Beers, D. (Key Personnel), Greene, E. P. (Key Personnel), Lai, E. C. (Key Personnel), Liao, B. (Key Personnel), Shroff, S. (Key Personnel) & Zhao, W. (Key Personnel)
8/13/20 → …
Project: Clinical Trial
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Phase IIa Double-Blind, Placebo-Controlled Study to Evaluate the Safety ofOral Fingolimod in Patients with ALS
Greene, E. P. (PI), Appel, S. H. (CoI) & Lai, E. C. (CoI)
Massachusetts General Hospital
5/13/13 → 5/12/38
Project: Non Profit
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CD4+ CD25+ regulatory T cells as Potential Biomarkers of Pathogenesis and Response to Therapy in CIDP Patients
Greene, E. P. (PI), Appel, S. H. (Project Director) & Lai, E. C. (Project Director)
GBS/CIDP Foundation International
8/22/12 → 6/30/14
Project: Non Profit
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LONG-TERM STUDY OF DEEP BRAIN STIMULATION FOR PARKINSON'S DISEASE: A LONGITUDINAL FOLOW-UP STUDY OF THE VA/NINDS CSP #468 COHORT
Lai, E. C. (PI) & Atassi, F. (CoI)
Chicago Assn for Res and Ed in Science
3/1/11 → 2/28/15
Project: Federal Funding Agencies
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Peripheral monocyte transcriptional signatures of inflammation and oxidative stress in Parkinson's disease
Thome, A. D., Wang, J., Atassi, F., Thonhoff, J. R., Faridar, A., Zhao, W., Beers, D. R., Lai, E. C. & Appel, S. H., Jul 23 2025, In: Frontiers in immunology. 16, p. 1571074Research output: Contribution to journal › Article › peer-review
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Peripheral monocyte transcriptional signatures of inflammation and oxidative stress in Parkinson’s disease
Thome, A. D., Wang, J., Atassi, F., Thonhoff, J. R., Faridar, A., Zhao, W., Beers, D. R., Lai, E. C. & Appel, S. H., 2025, In: Frontiers in immunology. 16, 1571074.Research output: Contribution to journal › Article › peer-review
Open Access -
Prevalence of Delirium After Abdominal Surgery and Association With Ketamine: A Retrospective, Propensity-Matched Cohort Study
Faisal, H., Qamar, F., Hsu, E. S., Xu, J., Lai, E. C., Wong, S. T. & Masud, F. N., Jan 11 2024, In: Critical care explorations. 6, 1, p. E1032Research output: Contribution to journal › Article › peer-review
Open Access -
Usability and Tolerability of Virtual Reality-Based Cognitive Stimulation in Healthy Elderly Volunteers—A Feasibility Clinical Trial
Faisal, H., Lim, W., Dattagupta, A., Lin, P., Gupta, R., Lai, E. C., Xu, J., Wong, S. T. & Masud, F. N., 2024, (Accepted/In press) In: Games for Health Journal. 14, 2, p. 136-145 10 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Performing Dynamic Weight-Shifting Balance Exercises With a Smartphone-Based Wearable Telerehabilitation System for Home Use by Individuals With Parkinson's Disease: A Proof-of-Concept Study
Lee, B. C., An, J., Kim, J. & Lai, E. C., 2023, In: IEEE Transactions on Neural Systems and Rehabilitation Engineering. 31, p. 456-463 8 p.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations
Prizes
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Honorary Professor of Qingdao Municipal Hospital, Qingdao University
Lai, E. C. (Recipient), Sep 2 2016
Prize: Appointment
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Houston Methodist GME Teaching Award
Lai, E. C. (Recipient), Jun 1 2016
Prize: Prize (including medals and awards)