Professional Information

Dr. Enrica De Rosa is the Director of the Intravital Microscopy Core and the Laboratory Manager of the Nanomedicine Department, at the Houston Methodist Research Institute.
At the Universita' degli Studi di Napoli Federico II she earned her BS and MS in Chemical Engineering in 2001, and in 2004 her PhD in Chemical, Material and Production Engineering, specializing in Biomaterial and Transport Phenomena. During her awarded fully funded PhD scholarship she set up and validated an advanced microscopy technique (FRAP-Fluorescence Recovery After Photobleaching) to locally measure molecular diffusion for drug delivery and tissue engineering application. In 2007 she moved to Houston as senior postdoc in the Nanomedicine department of University of Texas, where she pioneered the development of an implantable subcutaneous nanodevice for long term constant drug delivery and of a weight bearing bio-nano-material able to regenerate the bone tissue in a critical size bone fracture. Her research led to the publication of many papers in well-known peer-reviewed journals. In April 2009 she was awarded the Heinlein Trust Microgravity Award to reward innovation in the use of microgravity to advance biotech, nanotech, combustion, metallurgy, and other fields. Since 2011 she has supported the Nanomedicine department research as Laboratory Manager at the Houston Methodist Research Institute and managed the Intravital Microscopy Core.
With her proficiency in live microscopy she was able to image and quantify drug delivery, targeting accumulation and vessel formation, in several organ and tissues, such as skin, liver, pancreas, brain, muscle, ear, intestine, lymphonodes. One of her recent works published on Nature Materials demonstrated that prototype porous silicon nanoneedles are a new more effective gene delivery method, able to induce 6 fold increase of blood vessel formation in vivo; paving the way for using this platform to successfully promote tissue regeneration and integration of new organs and implants.
In 2016 launched the Intravital Microscopy apparatus as core of the HMRI and under her leadership, research and financial experience the core can offer exceptional IVM services, with cutting edge IVM technology and image analysis tools at competitive prices.

Keywords

    Research Area Keywords

  • Nanomedicine

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Nanoneedles
Concept: Nanoneedles
Weight: 100%
Domain: Engineering & Materials Science
Silicon
Concept: Silicon
Weight: 83%
Domain: Chemical Compounds
Biomimetics
Concept: Biomimetics
Weight: 55%
Domain: Chemical Compounds
Tissue
Concept: Tissue
Weight: 51%
Domain: Engineering & Materials Science
Nanoparticles
Concept: Nanoparticles
Weight: 48%
Domain: Chemical Compounds
Drug delivery
Concept: Drug delivery
Weight: 44%
Domain: Engineering & Materials Science
Proteins
Concept: Proteins
Weight: 44%
Domain: Engineering & Materials Science
oxaliplatin
Concept: oxaliplatin
Weight: 41%
Domain: Medicine & Life Sciences
Molecules
Concept: Molecules
Weight: 40%
Domain: Engineering & Materials Science
Membranes
Concept: Membranes
Weight: 38%
Domain: Chemical Compounds
Research OutputsResearch Output authored by Enrica De Rosa is tagged with the concept

Journals

ACS Nano

ISSNs: 1936-0851

Additional searchable ISSN (Electronic): 1936-086X

American Chemical Society

Journal

4

ACS Applied Materials and Interfaces

ISSNs: 1944-8244

Additional searchable ISSN (Electronic): 1944-8252

American Chemical Society

Journal

2

Advanced Functional Materials

ISSNs: 1616-301X

Additional searchable ISSN (Electronic): 1616-3028

Wiley

Journal

2

Nature Materials

ISSNs: 1476-1122

Additional searchable ISSN (Electronic): 1476-4660

Nature Publishing Group

Journal

2

Pharmaceutics

Additional searchable ISSN (Electronic): 1999-4923

Scopus rating (2018): CiteScore 4.58

Journal

1
has published Research OutputsResearch Output by Enrica De Rosa

Research Network

Visualization: Institutional Network

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Enrica De Rosa

Visualization: Co-author Network

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Enrica De Rosa

Shared Pub. Internal Organizations

Research Institute

Organizational unit: Institutes

21

Academic Institute

Organizational unit: Institutes

21

Department of Orthopedic Surgery

Organizational unit: Departments

13

Regenerative Medicine Program

Organizational unit: Programs

13

Houston Methodist Hospital

Organizational unit: Schools & Hospitals

10
has Research OutputsResearch Output by Enrica De Rosa

Shared Pub. External Organizations

Houston Methodist Hospital

External organization: Medical

7

Houston Methodist Research Institute

External organization: Unknown

6

Univ. of Texas

External organization: Unknown

4

University of Naples - Federico II

External organization: Unknown

4

University of Texas Health Science Center at Houston

External organization: Unknown

4
has Research OutputsResearch Output by Enrica De Rosa

Shared Pub. Internal co-authors

has co-authored Research OutputsResearch Output with Enrica De Rosa

Shared Pub. External co-authors

Jonathan O. Martinez

External person

7

Ciro Chiappini

External person

6

Roberto Molinaro

External person

6

P. Netti

External person

4

Claudia Corbo

External person

4
has co-authored Research OutputsResearch Output with Enrica De Rosa

ID: 51460662