Personal profile
Personal profile
Dr. Eleftherios Mylonakis, is Chair of Department of Medicine at Houston Methodist Hospital. Prior to joining HMH, Dr. Mylonakis was Charles C.J. Carpenter Professor of Infectious Disease and. Chief of Infectious Diseases at the Warren Alpert Medical School of Brown University where he was also Professor of Molecular Microbiology and Immunology and Assistant Dean for Longitudinal Medical Research. Prior to his 10 years at Brown, Dr. Mylonakis was Attending Physician at Massachusetts General Hospital and rose through the ranks at Harvard Medical School up to Associate Professor.
Research interests
Dr. Mylonakis studies host and microbial factors of infection and the discovery of antimicrobial agents. His research encompasses both clinical and laboratory studies and the use of mammalian and invertebrate model hosts systems to identify novel antimicrobial compounds and the elucidation of evolutionarily conserved aspects of microbial virulence and the host response. He has eight patents, has edited five books, and published over 450 articles in the peer-reviewed literature.
External positions
Professor of Medicine, Weill Cornell Medicine
Jul 1 2023 → …
Divisions
- Infectious Disease
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Collaborations and top research areas from the last five years
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Advances in methicillin-resistant Staphylococcus aureus drug discovery: developments and challenges
Vassilopoulos, S. & Mylonakis, E., Jan 23 2026, (E-pub ahead of print) In: Expert Opinion on Drug Discovery. 21, 2, p. 231-244 14 p.Research output: Contribution to journal › Review article › peer-review
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Arthropod-Derived Antimicrobial Peptides as Potential AMR Therapeutics: A Special Focus on the Lasioglossins
Kumar, A., Mishra, B., Mylonakis, E., Konar, A. & Basu, A., Jun 2026, In: Journal of Peptide Science. 32, 6, p. e70099 e70099.Research output: Contribution to journal › Review article › peer-review
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CAMPER: mechanistic artificial intelligence for designing peptides that target MRSA persisters
Shehadeh, F., Mishra, B., Ferrer-Espada, R., Basu, A., Felix, L. O., Dellis, C., Ganesan, N., Zhang, L., Martens, A. T., Goulev, Y., Sherman, M. B., Paulsson, J., Naik, M. T., Sotiriadis, P. P. & Mylonakis, E., Mar 9 2026, In: Nature Communications. 17, 1, 3689.Research output: Contribution to journal › Article › peer-review
Open Access -
Candesartan cilexetil disrupts methicillin-resistant Staphylococcus aureus membrane and potentiates gentamicin and polymyxin B activity
Tharmalingam, N., Kovacs, R. W., Scarpa de Mello, S., Baldwin, P. R., Jayanthan, H. S., Arulsamy, K., Rajmuthiah, R., Rossatto, F. C. P., Manz, K. E., DeGiorgis, J. A., Acevedo, O., Gilmore, M. S., Ludtke, S. J., Pennell, K. D., Ausubel, F. M. & Mylonakis, E., Mar 15 2026, In: Nature Communications. 17, 1, 4012.Research output: Contribution to journal › Article › peer-review
Open Access -
Effect of background asthma and atopic conditions on prophylaxis and treatment of COVID-19 infection
Chen, R., Lyu, J., Talapatra, K., Ali, S., Mylonakis, E., Norton, T. D. & Geba, G. P., Feb 28 2026, (E-pub ahead of print) In: Annals of Allergy, Asthma and Immunology. 136, 6, p. 671-680.e4Research output: Contribution to journal › Article › peer-review
Open Access
Prizes
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Presidential Award - NIH Competitiveness
Mylonakis, E. (Recipient), 2024
Prize: Prize (including medals and awards)