Projects per year
Personal profile
Personal profile
Dr. Eleftherios Mylonakis, is Chair of Department of Medicine at Houston Methodist Hospital. Prior to joining HMH, Dr. Mylonakis was Charles C.J. Carpenter Professor of Infectious Disease and. Chief of Infectious Diseases at the Warren Alpert Medical School of Brown University where he was also Professor of Molecular Microbiology and Immunology and Assistant Dean for Longitudinal Medical Research. Prior to his 10 years at Brown, Dr. Mylonakis was Attending Physician at Massachusetts General Hospital and rose through the ranks at Harvard Medical School up to Associate Professor.
Research interests
Dr. Mylonakis studies host and microbial factors of infection and the discovery of antimicrobial agents. His research encompasses both clinical and laboratory studies and the use of mammalian and invertebrate model hosts systems to identify novel antimicrobial compounds and the elucidation of evolutionarily conserved aspects of microbial virulence and the host response. He has eight patents, has edited five books, and published over 450 articles in the peer-reviewed literature.
External positions
Professor of Medicine, Weill Cornell Medicine
Jul 1 2023 → …
Divisions
- Infectious Disease
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Collaborations and top research areas from the last five years
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Sepsis-Induced Immune Paralysis
Gotur, D. B. (PI) & Mylonakis, E. (Key Personnel)
9/11/25 → …
Project: Clinical Trial
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SciClone-Thymalfasin (thymosin alpha 1; Ta1) as an enhancer of vaccine response among older adults receiving booster doses of COVID-19
Mylonakis, E. (PI), Gotur, D. B. (Key Personnel) & Youssef, J. G. (Key Personnel)
10/30/24 → …
Project: Clinical Trial
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Natural Phenolic Compounds against Oral Candidiasis (OC)
Mylonakis, E. (PI)
8/9/24 → 7/31/29
Project: Federal Funding Agencies
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RECOVER-SLEEP: A Platform Protocol for Evaluation of Interventions for Sleep Disturbances in Post-Acute Sequelae of SARS-CoV-2 Infection (PASC)
Mylonakis, E. (PI)
4/30/24 → 12/31/26
Project: Federal Funding Agencies
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Structural and functional alterations in mitochondria of patients with multi-organ injury and sepsis
Gotur, D. B. (PI), Hamilton, D. J. (Key Personnel) & Mylonakis, E. (Key Personnel)
4/3/24 → …
Project: Clinical Trial
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Antimicrobial peptide developed with machine learning sequence optimization targets drug resistant Staphylococcus aureus in mice
Mishra, B., Basu, A., Shehadeh, F., Felix, L. O., Kollala, S. S., Chhonker, Y. S., Naik, M. T., Dellis, C., Zhang, L., Ganesan, N., Murry, D. J., Gu, J., Sherman, M. B., Ausubel, F. M., Sotiriadis, P. P. & Mylonakis, E., Jun 16 2025, In: Journal of Clinical Investigation. 135, 12, e185430.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Comparative Efficacy of Treatment Regimens for Chronic Hepatitis D Virus Infection: A Systematic Review and Network Meta-Analysis
Ouranos, K., Mylona, E. K., Dellis, C., Bakaloudi, D. R., Shehadeh, F., Noureddin, M., Kalligeros, M. & Mylonakis, E., Aug 2025, In: Liver International. 45, 8, e70232.Research output: Contribution to journal › Article › peer-review
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Evaluating Short-course Antibiotic Therapy for Pediatric Community-acquired Pneumonia: A Systematic Review and Meta-analysis
Bolormaa, E., Kang, C. R., Choe, Y. J., Yoo, Y., Lee, J. S., Park, J. Y., Choe, S. A., Tansarli, G. S. & Mylonakis, E., Jul 2025, In: Pediatric Infectious Disease Journal. 44, 7, p. 637-644 8 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Evaluation of the Feasibility and Efficacy of Point-of-Care Antibody Tests for Biomarker-Guided Management of Coronavirus Disease 2019
Reilly, C., Mylonakis, E., Dewar, R., Young, B., Nordwall, J., Bhagani, S., Chia, P. Y., Davis, R., Files, C., Ginde, A. A., Hatlen, T., Helleberg, M., Hayanga, A., Jensen, T. O., Jain, M. K., Kalomenidis, I., Kim, K., Lallemand, P., Lindegaard, B. & Menon, A. & 22 others, , Mar 15 2025, In: Journal of Infectious Diseases. 231, 3, p. 677-683 7 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Gellan gum formulations containing natural polyphenolic compounds to treat oral candidiasis
Ganesan, N., Felix, L. O., Mishra, B., Zhang, L., Dellis, C., Shehadeh, F., Wu, D., Cruz, L. A., Arce, R. M. & Mylonakis, E., Sep 2025, In: Microbiology Spectrum. 13, 9, e00798-25.Research output: Contribution to journal › Article › peer-review
Open Access
Prizes
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Presidential Award - NIH Competitiveness
Mylonakis, E. (Recipient), 2024
Prize: Prize (including medals and awards)