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Research Area Keywords
- Neurosciences
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Projects
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Dr. Appel_Biomarker Study_ALS and other Neurologic Diseases
Appel, S. H., Beers, D., Greene, E. P., Lai, E. C., Liao, B., Shroff, S., Thonhoff, J. R. & Zhao, W.
8/13/20 → …
Project: Clinical Trial
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Immune Mechanisms in Amyotrophic Lateral Sclerosis
Appel, S. H., Beers, D. & Zhao, W.
Muscular Dystrophy Association
5/1/14 → 4/30/17
Project: Non Profit
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Blocking TLR-Activation of Regulatory T cells Slows Disease in ALS
Appel, S. H., Beers, D. & Zhao, W.
Natl Inst of Neuro Disorders and Stroke
3/15/13 → 8/31/15
Project: Federal Funding Agencies
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Using CD4+T Cells as a candidate therapy to slow disease progression in ALS
Appel, S. H., Beers, D. & Zhao, W.
Natl Inst of Neuro Disorders and Stroke
2/15/10 → 4/30/12
Project: Federal Funding Agencies
Research Output
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Elevated acute phase proteins reflect peripheral inflammation and disease severity in patients with amyotrophic lateral sclerosis
Beers, D. R., Zhao, W., Neal, D. W., Thonhoff, J. R., Thome, A. D., Faridar, A., Wen, S., Wang, J. & Appel, S. H., Sep 17 2020, In : Scientific Reports. 10, 1, p. 15295 15295.Research output: Contribution to journal › Article
Open Access -
Immunosuppressive Functions of M2 Macrophages Derived from iPSCs of Patients with ALS and Healthy Controls
Zhao, W., Beers, D. R., Thonhoff, J. R., Thome, A. D., Faridar, A., Wang, J., Wen, S., Ornelas, L., Sareen, D., Goodridge, H. S., Svendsen, C. N. & Appel, S. H., Jun 26 2020, In : iScience. 23, 6, 101192.Research output: Contribution to journal › Article
2 Scopus citations -
Restoring regulatory T-cell dysfunction in Alzheimer's disease through ex vivo expansion
Faridar, A., Thome, A. D., Zhao, W., Thonhoff, J. R., Beers, D. R., Pascual, B., Masdeu, J. C. & Appel, S. H., 2020, In : Brain communications. 2, 2, p. fcaa112Research output: Contribution to journal › Article
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Head-to-head comparison of 11C-PBR28 and 11C-ER176 for quantification of the translocator protein in the human brain
Zanotti-Fregonara, P., Pascual, B., Veronese, M., Yu, M., Beers, D., Appel, S. H. & Masdeu, J. C., Aug 1 2019, In : European Journal of Nuclear Medicine and Molecular Imaging. 46, 9, p. 1822-1829 8 p.Research output: Contribution to journal › Article
5 Scopus citations -
Immune dysregulation in amyotrophic lateral sclerosis: mechanisms and emerging therapies
Beers, D. R. & Appel, S. H., Feb 2019, In : The Lancet Neurology. 18, 2, p. 211-220 10 p.Research output: Contribution to journal › Review article
40 Scopus citations