Dale J. Hamilton, MD

  • 814 Citations
  • 15 h-Index
20042020

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Article
2020

Discovery of class i histone deacetylase inhibitors based on romidpesin with promising selectivity for cancer cells

Zhang, K., Yao, Y., Tu, Z., Liao, C., Wang, Z., Qiu, Y., Chen, D., Hamilton, D. J., Li, Z. & Jiang, S., Feb 2020, In : Future Medicinal Chemistry. 12, 4, p. 311-323 13 p.

Research output: Contribution to journalArticle

1 Scopus citations
2019

Cholesterol Induces CD8+ T Cell Exhaustion in the Tumor Microenvironment

Ma, X., Bi, E., Lu, Y., Su, P., Huang, C., Liu, L., Wang, Q., Yang, M., Kalady, M. F., Qian, J., Zhang, A., Gupte, A. A., Hamilton, D. J., Zheng, C. & Yi, Q., Jul 2 2019, In : Cell Metabolism. 30, 1, p. 143-156.e5

Research output: Contribution to journalArticle

36 Scopus citations

Glycolytic Switch Is Required for Transdifferentiation to Endothelial Lineage

Lai, L., Reineke, E. L., Hamilton, D. J. & Cooke, J. P., Jan 2 2019, In : Circulation. 139, 1, p. 119-133 15 p.

Research output: Contribution to journalArticle

6 Scopus citations

Single-Molecule Force Measurement Guides the Design of Multivalent Ligands with Picomolar Affinity

Yang, Z., Jiang, S., Li, F., Qiu, Y., Gu, J., Pettigrew, R. I., Ferrari, M., Hamilton, D. J. & Li, Z., Apr 8 2019, In : Angewandte Chemie - International Edition. 58, 16, p. 5272-5276 5 p.

Research output: Contribution to journalArticle

4 Scopus citations

The Role of Estrogen in Protection of Skeletal Muscle Function in Diastolic Dysfunction

Chatterjee, S., Li, S., Zhang, A., Vedula, I., AlRukby, J., Hamilton, D. J. & Gupte, A. A., Jul 29 2019, In : Circulation Research. 125

Research output: Contribution to journalArticle

2018

Improved cardiovascular function in old mice after N-Acetyl cysteine and glycine supplemented diet: Inflammation and mitochondrial factors

Cieslik, K. A., Sekhar, R. V., Granillo, A., Reddy, A., Medrano, G., Heredia, C. P., Entman, M. L., Hamilton, D. J., Li, S., Reineke, E. L., Gupte, A. A., Zhang, A. & Taffet, G., 2018, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 73, 9, p. 1167-1177 11 p.

Research output: Contribution to journalArticle

7 Scopus citations

Improved Cardiovascular Function in Old Mice After N-Acetyl Cysteine and Glycine Supplemented Diet: Inflammation and Mitochondrial Factors

Cieslik, K. A., Sekhar, R. V., Granillo, A., Reddy, A., Medrano, G., Heredia, C. P., Entman, M. L., Hamilton, D. J., Li, S., Reineke, E., Gupte, A. A., Zhang, A. & Taffet, G. E., Aug 10 2018, In : The journals of gerontology. Series A, Biological sciences and medical sciences. 73, 9, p. 1167-1177 11 p.

Research output: Contribution to journalArticle

Polymer Functionalization of Isolated Mitochondria for Cellular Transplantation and Metabolic Phenotype Alteration

Wu, S., Zhang, A., Li, S., Chatterjee, S., Qi, R., Segura-Ibarra, V., Ferrari, M., Gupte, A., Blanco, E. & Hamilton, D. J., Mar 1 2018, In : Advanced Science. 5, 3, p. 1700530-n/a 1700530.

Research output: Contribution to journalArticle

7 Scopus citations
2017
74 Scopus citations

Tead1 is required for maintaining adult cardiomyocyte function, and its loss results in lethal dilated cardiomyopathy

Liu, R., Lee, J., Kim, B. S., Wang, Q., Buxton, S. K., Balasubramanyam, N., Kim, J. J., Dong, J., Zhang, A., Li, S., Gupte, A. A., Hamilton, D. J., Martin, J. F., Rodney, G. G., Coarfa, C., Wehrens, X. H., Yechoor, V. K. & Moulik, M., Sep 7 2017, In : JCI insight. 2, 17

Research output: Contribution to journalArticle

10 Scopus citations

The Failing Heart: Energy Supply, Processing, and Transfer

Hamilton, D. J., Apr 18 2017, In : Methodist DeBakey cardiovascular journal. 13, 1, p. 3

Research output: Contribution to journalArticle

2016
15 Scopus citations

Estrogen receptor alpha activation enhances mitochondrial function and systemic metabolism in high fat-fed ovariectomized mice.

Hamilton, D. J., Minze, L. J., Cao, T. N., Lyon, C. J., Geiger, P. C., Hsueh, W. A. & Gupte, A. A., Apr 2016, In : Physiological Reports. 4, 17, p. e12913

Research output: Contribution to journalArticle

25 Scopus citations

Full expression of cardiomyopathy is partly dependent on B-cells: A pathway that involves cytokine activation, immunoglobulin deposition, and activation of apoptosis

Cordero-Reyes, A. M., Youker, K. A., Trevino, A. R., Celis, R., Hamilton, D. J., Flores-Arredondo, J. H., Orrego, C. M., Bhimaraj, A., Estep, J. D. & Torre-Amione, G., 2016, In : Journal of the American Heart Association. 5, 1, p. 1-12 12 p.

Research output: Contribution to journalArticle

35 Scopus citations

Molecular Imaging and Precision Medicine

Gupte, A. A. & Hamilton, D. J., Feb 1 2016, In : Cardiology. 133, 3, p. 178-180 3 p.

Research output: Contribution to journalArticle

5 Scopus citations
2015

A PKM2 signature in the failing heart

Rees, M. L., Subramaniam, J., Li, Y., Hamilton, D. J., Frazier, O. H. & Taegtmeyer, H., Apr 10 2015, In : Biochemical and Biophysical Research Communications. 459, 3, p. 430-436 7 p.

Research output: Contribution to journalArticle

29 Scopus citations

Differential mitochondrial function in remodeled right and non-remodeled left ventricles in pulmonary hypertension.

Gupte, A. A., Cordero-Reyes, A. M., Youker, K., Matsunami, R. K., Engler, D. A., Loebe, M., Ashrith, G., Torre, G. & Hamilton, D. J., Sep 2015, In : Journal of Cardiac Failure. p. Epub

Research output: Contribution to journalArticle

Hypertensive Emergency Following Embolization of a Large Adrenal Myelolipoma_Adrenal Medullary Infarction, Pheochromocytoma or Acute Sympathetic Discharge?

Ansari, M., Dela Garza, M., Deavers, M., Balogh, J., Rosenberg, W. R., Hai, S., Ruppe, M. & Hamilton, D. J., 2015, In : AACE Clinical Case Reports. 1, 4, p. e216-e220 5 p.

Research output: Contribution to journalArticle

2014

Freshly isolated mitochondria from failing human hearts exhibit preserved respiratory function

Cordero-Reyes, A. M., Gupte, A. A., Youker, K. A., Loebe, M., Hsueh, W. A., Torre-Amione, G., Taegtmeyer, H. & Hamilton, D. J., Mar 2014, In : Journal of Molecular and Cellular Cardiology. 68, p. 98-105 8 p.

Research output: Contribution to journalArticle

34 Scopus citations

Mechanical unloading promotes myocardial energy recovery in human heart failure

Gupte, A. A., Hamilton, D. J., Cordero-Reyes, A. M., Youker, K. A., Yin, Z., Estep, J. D., Stevens, R. D., Wenner, B., Ilkayeva, O., Loebe, M., Peterson, L. E., Lyon, C. J., Wong, S. T. C., Newgard, C. B., Torre-Amione, G., Taegtmeyer, H. & Hsueh, W. A., Jun 2014, In : Circulation: Cardiovascular Genetics. 7, 3, p. 266-276 11 p.

Research output: Contribution to journalArticle

40 Scopus citations

Transcriptome analysis of human adipocytes implicates the NOD-like receptor pathway in obesity-induced adipose inflammation

Yin, Z., Deng, T., Peterson, L. E., Yu, R., Lin, J., Hamilton, D. J., Reardon, P. R., Sherman, V., Winnier, G., Zhan, M., Lyon, C. J., Wong, S. T. C. & Hsueh, W. A., Aug 25 2014, In : Molecular and cellular endocrinology. 394, 1-2, p. 80-87 8 p.

Research output: Contribution to journalArticle

36 Scopus citations
2013

Class II major histocompatibility complex plays an essential role in obesity-induced adipose inflammation

Deng, T., Lyon, C. J., Minze, L. J., Lin, J., Zou, J., Liu, J. Z., Ren, Y., Yin, Z., Hamilton, D. J., Reardon, P. R., Sherman, V., Wang, H. Y., Phillips, K. J., Webb, P., Wong, S. T. C., Wang, R. F. & Hsueh, W. A., Mar 5 2013, In : Cell Metabolism. 17, 3, p. 411-422 12 p.

Research output: Contribution to journalArticle

184 Scopus citations

High-fat feeding-induced hyperinsulinemia increases cardiac glucose uptake and mitochondrial function despite peripheral insulin resistance

Gupte, A. A., Minze, L. J., Reyes, M., Ren, Y., Wang, X., Brunner, G., Ghosn, M., Cordero-Reyes, A. M., Ding, K., Pratico, D., Morrisett, J., Shi, Z. Z., Hamilton, D. J., Lyon, C. J. & Hsueh, W. A., Aug 1 2013, In : Endocrinology. 154, 8, p. 2650-2662 13 p.

Research output: Contribution to journalArticle

20 Scopus citations
2009

Prospects for future advancements in islet cell transplantation

Sabek, O., Hamilton, D. J. & Gaber, A. O., Feb 1 2009, In : Minerva Chirurgica. 64, 1, p. 59-73 15 p.

Research output: Contribution to journalArticle

3 Scopus citations
2004

Achievement of insulin independence via pancreatic islet transplantation using a remote isolation center: A first-year review

Barshes, N. R., Lee, T., Goodpasture, S., Brunicardi, F. C., Alejandro, R., Ricordi, C., Soltes, G., Barth, M., Hamilton, D. J. & Goss, J. A., May 1 2004, In : Transplantation Proceedings. 36, 4, p. 1127-1129 3 p.

Research output: Contribution to journalArticle

35 Scopus citations

Development of a human pancreatic islet-transplant program through a collaborative relationship with a remote islet-isolation center

Goss, J. A., Goodpastor, S. E., Brunicardi, F. C., Barth, M. H., Soltes, G. D., Garber, A. J., Hamilton, D. J., Alejandro, R. & Ricordi, C., Feb 15 2004, In : Transplantation. 77, 3, p. 462-466 5 p.

Research output: Contribution to journalArticle

57 Scopus citations