Projects per year
Personal profile
Personal profile
Dr. Cesar Arias has over 25 years of experience in the field of antimicrobial resistance. His career has focused on the clinical and molecular aspects of antimicrobial resistance (AMR) with emphasis on gram-positive organisms. He became interested in infectious disease (ID) because of its prominence as a public health problem and also because ID spans all aspects of clinical medicine. After medical school, he attended the University of London where he focused on clinical microbiology and performed research on the molecular biology of capsule genes in S. pneumoniae, developing molecular tools for capsule typing of this important pathogen. He obtained his PhD at Cambridge in 2000, studying the molecular mechanisms of vancomycin resistance in enterococci. During graduate studies, he discovered a new enzyme and elucidated a novel mechanism for synthesis of D-serine in bacteria. After completing residency at UTHealth McGovern Medical School as well as a fellowship in ID (joint program with UT MD Anderson Cancer Center), he expanded studies on staphylococci and enterococci.
He was the recipient of a K99/R00 NIH Pathway to Independence Award and now holds an NIH K24 mid-career investigator award to increase patient-oriented and mentoring activities on antimicrobial resistance. He has also founded two overseas research units (Molecular Genetics and Antimicrobial Resistance Unit and the International Center for Microbial Genomics) focused on AMR at Universidad El Bosque, Bogota, Colombia. His most recent research has concentrated on elucidating the mechanistic basis of resistance to daptomycin with focus on enterococci and to dissect the molecular epidemiology and clinical impact of multidrug-resistant organisms as part of the NIH-funded Antimicrobial Resistance Leadership Group. A major component of the research on MDR organisms is the use of genomics as a major tool to dissect the molecular epidemiology and population structure of MDR bacteria.
External positions
Professor of Medicine, Weill Cornell Medical College
Oct 1 2022 → …
Research Area Keywords
- Infectious Disease & Pathology
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Collaborations and top research areas from the last five years
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Antimicrobial Resistance Training Program in the Texas Medical Center (AMR-TPT)
7/1/24 → 6/30/29
Project: Federal Funding Agencies
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POR and Training Program on Multidrug-Resistant Organisms
7/1/22 → 6/30/26
Project: Federal Funding Agencies
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VENOUS: A translational study of enterococcal bacteremia
6/1/22 → 5/31/25
Project: Federal Funding Agencies
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Dynamics of Colonization and Infection by Multidrug-resistant Pathogens in Immunocompromised and Critically Ill Patients (DYNAMITE)
9/1/21 → 7/31/26
Project: Federal Funding Agencies
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A rapid host–protein test for differentiating bacterial from viral infection: Apollo diagnostic accuracy study
Bachur, R. G., Kaplan, S. L., Arias, C. A., Ballard, N., Carroll, K. C., Cruz, A. T., Gordon, R., Halabi, S., Harris, J. D., Hulten, K. G., Jacob, T., Kellogg, M. D., Klein, A., Mishan, P. S., Motov, S. M., Peck-Palmer, O. M., Ryan, L. M., Shapira, M., Suits, G. S., Wang, H. E., & 2 others , Jun 2024, In: Journal of the American College of Emergency Physicians Open. 5, 3, p. e13167 e13167.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Clinical Features and Genomic Epidemiology of Bloodstream Infections due to Enterococcal Species Other Than Enterococcus faecalis or E. faecium in Patients With Cancer
Axell-House, D. B., Ashley, P. A., Egge, S. L., Tran, T. T., Pedroza, C., Zhang, M., Dinh, A. Q., Simar, S. R., Sahasrabhojane, P. V., Miller, W. R., Shelburne, S. A., Hanson, B. M. & Arias, C. A., Jun 1 2024, In: Open Forum Infectious Diseases. 11, 6, p. ofae288Research output: Contribution to journal › Article › peer-review
Open Access -
Differential in vitro susceptibility to ampicillin/ceftriaxone combination therapy among Enterococcus faecalis infective endocarditis clinical isolates
Westbrook, K. J., Chilambi, G. S., Stellfox, M. E., Nordstrom, H. R., Li, Y., Iovleva, A., Shah, N. H., Jones, C. E., Kline, E. G., Squires, K. M., Miller, W. R., Tran, T. T., Arias, C. A., Doi, Y., Shields, R. K. & Tyne, D. V., Apr 1 2024, In: Journal of Antimicrobial Chemotherapy. 79, 4, p. 801-809 9 p.Research output: Contribution to journal › Article › peer-review
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ESKAPE pathogens: antimicrobial resistance, epidemiology, clinical impact and therapeutics
Miller, W. R. & Arias, C. A., Oct 2024, In: Nature Reviews Microbiology. 22, 10, p. 598-616 19 p.Research output: Contribution to journal › Review article › peer-review
24 Scopus citations -
Increased mortality in hospital- compared to community-onset carbapenem-resistant enterobacterales infections
Antibacterial Resistance Leadership Group , Sep 5 2024, (E-pub ahead of print) In: The Journal of antimicrobial chemotherapy.Research output: Contribution to journal › Article › peer-review