Bruna Corradetti, PhD, MSc

  • 969 Citations
  • 21 h-Index
20082020

Research output per year

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Personal profile

Personal profile

Bruna Corradetti received a Ph.D. in Biomolecular Science from Polytechnic University of Marche (Italy) in 2012 working on the development of stem cell-based therapeutic approaches for the treatment of spontaneous tendon injuries. In 2013 she was appointed as Assistant Professor in Genetics in the same university and joined the Houston Methodist Research Institute in the context of a Fellowship for Molecular Medicine. There, Dr. Corradetti expanded her research to material science and nanotechnology and to their applications in the fields of tissue engineering, regenerative medicine, and immunomodulation. She conceived and developed naturally inspired platforms and delivery systems able to support tissue regeneration by modulating stem and immune cells behavior. Since 2015 Dr. Corradetti has served as Associate Member for the Houston Methodist Research Institute and in 2016 as Visiting Professor at the Department of Mechanics and Materials at ETH Zurich working with Prof. Chiara Daraio.

In 2016 Dr. Corradetti was nominated Fellow of the Academy of Translational Medicine Professionals and since then she serves as Secretary of the European Society for Translational Medicine. In 2017 Dr. Corradetti has been recognized among the “100 Italian Excellences.” Dr. Corradetti has published more than 40 peer-reviewed papers and served as the sole Editor of the book entitled “The Immune Response to Implanted Materials and Devices. The Impact of the Immune System on the Success of an Implant” published by Springer International in 2017.

In 2018 Dr. Corradetti has joined the Houston Methodist Research Institute as Assistant Research Professor and was appointed as Associate Professor in the School of Medicine at Swansea University (Wales, UK). Her work is partially supported through the Sêr Cymru II program, funded by the European Commission through the Horizon 2020 Marie Skłodowska-Curie Actions (MSCA) COFUND scheme and the Welsh European Funding Office (WEFO) under the European Regional Development Fund (ERDF).

Research interests

- Natural and bio-inspired artificial platforms for the delivery of RNA therapeutics.

- Biomimetic strategies to improve tissue regeneration and modulate the immune response.

- Synthetic biomimetic extracellular matrices for the healing of chronic wounds and cell transplantation.

- Development of exosome-based vaccines to induce anti-cancer immune response.

Education/Academic qualification

PhD, Universitá Politecnica delle Marche

20092012

Biotechnology, MSc, Universitá Politecnica delle Marche

20062008

Biology, BS, Università Politecnica delle Marche

20002005

External positions

Adjunct Associate Professor, Swansea University

Jul 16 2018 → …

Research Area Keywords

  • Nanomedicine
  • Regenerative Medicine
  • Immunobiology & Inflammation
  • Cancer
  • Molecular Medicine

Free-text keywords

  • Exosomes
  • Stem cells
  • Tissue engineering
  • Immunomodulation
  • Immunotherapy
  • Ovarian cancer
  • Macrophages
  • RNA therapeutics

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Projects

Research Output

Enhanced In Vivo Vascularization of 3D-Printed Cell Encapsulation Device Using Platelet-Rich Plasma and Mesenchymal Stem Cells

Paez-Mayorga, J., Capuani, S., Farina, M., Lotito, M. L., Niles, J. A., Salazar, H. F., Rhudy, J., Esnaola, L., Chua, C. Y. X., Taraballi, F., Corradetti, B., Shelton, K. A., Nehete, P. N., Nichols, J. E. & Grattoni, A., Oct 1 2020, In : Advanced Healthcare Materials. 9, 19, 2000670.

Research output: Contribution to journalArticle

  • FGF-2-Induced Human Amniotic Mesenchymal Stem Cells Seeded on a Human Acellular Amniotic Membrane Scaffold Accelerated Tendon-to-Bone Healing in a Rabbit Extra-Articular Model

    Zhang, J., Liu, Z., Li, Y., You, Q., Yang, J., Jin, Y., Zou, G., Tang, J., Ge, Z., Liu, Y. & Corradetti, B., 2020, In : Stem Cells International. 2020, 4701476.

    Research output: Contribution to journalArticle

  • Immunotherapeutic Transport Oncophysics: Space, Time, and Immune Activation in Cancer

    Nizzero, S., Shen, H., Ferrari, M. & Corradetti, B., Jan 1 2020, In : Trends in Cancer. 6, 1, p. 40-48 9 p.

    Research output: Contribution to journalReview article

  • Neovascularized implantable cell homing encapsulation platform with tunable local immunosuppressant delivery for allogeneic cell transplantation

    Paez-Mayorga, J., Capuani, S., Hernandez, N., Farina, M., Chua, Y. X., Blanchard, R., Sizovs, A., Liu, H. C., Fraga, D. W., Niles, J. A., Salazar, H. F., Corradetti, B., Sikora, A. G., Kloc, M., Li, X. C., Gaber, A. O., Nichols, J. & Grattoni, A., Oct 2020, In : Biomaterials. 257, 120232.

    Research output: Contribution to journalArticle

  • 1 Scopus citations

    Bioactive Immunomodulatory Compounds: A Novel Combinatorial Strategy for Integrated Medicine in Oncology? BAIC Exposure in Cancer Cells

    Corradetti, B., Vaiasicca, S., Mantovani, M., Virgili, E., Bonucci, M. & Hammarberg Ferri, I., Aug 1 2019, In : Integrative Cancer Therapies. 18

    Research output: Contribution to journalArticle

  • 2 Scopus citations

    Prizes

    "100 Italian Excellence" award

    Corradetti, Bruna (Recipient), Nov 2017

    Prize: National/international honor

    BPW-CUP leadership award

    Corradetti, Bruna (Recipient), Oct 19 2019

    Prize: Prize (including medals and awards)

  • Co-Fund Fellowship

    Corradetti, Bruna (Recipient), Aug 1 2018

    Prize: Fellowship awarded competitively

  • Fellowship in Molecular Medicine

    Corradetti, Bruna (Recipient), Dec 2012

    Prize: Fellowship awarded competitively

  • MAPTA Postdoctoral Summer Travel Award

    Corradetti, Bruna (Recipient), Jul 2014

    Prize: Prize (including medals and awards)