Antonio Gotto, MD, DPhil

  • 75439 Citations
  • 98 h-Index
1958 …2020

Research output per year

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Personal profile

Personal profile

Dr. Antonio M. Gotto is the Stephen and Suzanne Weiss Dean of Weill Cornell Medical College in New York, New York, where he is also Professor of Medicine. In addition, Dr. Gotto is Provost for Medical Affairs of Cornell University. He joined Houston Methodist Research Institute in 2011. Previously, at Baylor College of Medicine in Houston, Texas, he was the Bob and Vivian Smith Professor and Chairman of the Department of Medicine, Scientific Director of the DeBakey Heart Center, and the JS Abercrombie Chair for Atherosclerosis and Lipoprotein Research. He also served as Chief of the Internal Medicine Service at The Methodist Hospital in Houston. Dr. Gotto's postgraduate work included doctoral studies at Oxford University in England as a Rhodes Scholar, and residency training at the Massachusetts General Hospital in Boston, Massachusetts.

As a lifelong supporter of educational efforts aimed at cardiovascular risk reduction, Dr. Gotto has been National President of the American Heart Association and President of the International Atherosclerosis Society. He is a member of the Institute of Medicine and the American Academy of Arts and Sciences and a recipient of many honors, including the Gold Heart Award from the American Heart Association, the 2000 Distinguished Alumnus award from Vanderbilt University and the Vanderbilt University School of Medicine, honorary doctoral degrees from the University of Bologna and Abilene Christian University, honorary professorships from the University of Buenos Aires and Francisco Marroquin University (Guatemala), and the Order of the Lion from the Republic of Finland. Dr. Gotto was the 2004 recipient of the International Okamoto Award from the Japan Vascular Disease Research Foundation. In 2004 Dr. Gotto was also named Honorary Member of the Society for Progress in Internal Medicine (Ludwig Heilmeyer Society) in Germany. In 2010, he received the Maurice R. Greenberg Distinguished Service Award, the highest honor bestowed by New York-Presbyterian/Weill Cornell on members of the medical staff.

Dr. Gotto speaks nationally and internationally on cardiovascular disease and has contributed more than 500 scholarly articles and books to the medical literature. In addition, he is coauthor of a series of books that explain the origins and treatment of cardiovascular disease to the general public.

Research interests

In the field of atherosclerosis, his basic science research interests include clinical disorders of lipid transport and the structure, metabolism, and function of lipoproteins and apolipoproteins. He and his associates were the first to achieve complete synthesis of a plasma apolipoprotein (apo C-I); they also determined the complete cDNA and amino acid sequence of apo B-100, one of the largest proteins ever sequenced and a key protein in atherosclerosis. In addition, Dr. Gotto has played a leading role in several landmark clinical trials demonstrating that cholesterol-lowering drug treatment can reduce the risk of heart disease.

Education/Academic qualification

MD, Vanderbilt University

Jul 1 1961Jun 30 1965

Award Date: Jun 30 1965

Biochemistry, D Phil, University of Oxford

Free-text keywords

  • Lipoproteins and apolipoproteins
  • Atherosclerosis
  • Lipid metabolism
  • Statins

Research Area Keywords

  • Heart & Vascular
  • Clinical Care
  • Clinical Translation & Trials

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Research Output

Association of Bempedoic Acid Administration with Atherogenic Lipid Levels in Phase 3 Randomized Clinical Trials of Patients with Hypercholesterolemia

Banach, M., Duell, P. B., Gotto, A., Laufs, U., Leiter, L. A., Mancini, G. B. J., Ray, K. K., Flaim, J. A., Ye, Z. & Catapano, A. L., Jan 1 2020, In : JAMA Cardiology.

Research output: Contribution to journalArticle

  • The alcohol–high-density lipoprotein athero-protective axis

    Rosales, C., Gillard, B. K., Gotto, A. & Pownall, H. J., Jul 1 2020, In : Biomolecules. 10, 7, p. 1-16 16 p., 987.

    Research output: Contribution to journalReview article

  • Cholesterol: Can't Live With It, Can't Live Without It

    Pownall, H. J. & Gotto, A., Jan 1 2019, In : Methodist DeBakey cardiovascular journal. 15, 1, p. 9-15 7 p.

    Research output: Contribution to journalReview article

  • 1 Scopus citations

    Efficacy and safety of statin therapy in older people: a meta-analysis of individual participant data from 28 randomised controlled trials

    Cholesterol Treatment Trialists' Collaboration, Feb 2 2019, In : The Lancet. 393, 10170, p. 407-415 9 p.

    Research output: Contribution to journalArticle

  • 121 Scopus citations

    Intensive Lipid Lowering in Elderly Patients

    Gotto, A. M., Sep 2019, In : JAMA Cardiology. 4, 9, p. 855-856 2 p.

    Research output: Contribution to journalComment/debate

    3 Scopus citations