Aaron D. Thome, Ph.D. grew up in Houston, Texas and completed his bachelor's degree in Biomedical Science at Texas A&M University in College Station, Texas. Following this, he completed his doctorate work at the Center for Neurodegeneration and Experimental Therapeutics (CNET) at the University of Alabama at Birmingham (UAB).  Dr. Thome's research here focused on microglial and neuroinflammatory mechanisms attributed to alpha-synuclein in models of Parkinson's disease. He then completed his Edwards Post-Doctoral Fellowship at the Houston Methodist Neurological Institute under Stanley H. Appel, M.D., the Edwards Distinguished Endowed Chair for ALS and Stanley H. Appel Department of Neurology Chair. Dr. Thome is currently primary faculty in the Houston Methodist Neurological Institute, Stanley H. Appel Department of Neurology, and Assistant Research Member for the Houston Methodist Research Institute.

Current research interest involves elucidating the underlying neuroinflammatory mechanisms in neurodegenerative disease, specifically in Parkinson's and Alzheimer's disease. His research utilizes human clinical samples and mouse pre-clinical models of disease to identify stage-specific immune changes in neurodegeneration and to develop translational therapeutics for immune modulation to target disease progression.