Houston Methodist

Projects

Projects per year 2000 2013 2016 2018 2019 2020 2021 2022 2023 2024 2046

• 192 Not started
• 536 Active
• 818 Finished

Projects per year

Search results

• Active

  Role of tumor microenvironment-derived cholesterol in CD8+ T-cell exhaustion

  Yi, Q. (PI)

  8/1/19 → 7/31/25

  Project: Federal Funding Agencies

• Anticoagulation in Intracerebral Hemorrhage (ICH) Survivors for Stroke Prevention and Recovery (ASPIRE)

  Britz, G. W. (PI)

  7/1/19 → 4/30/26

  Project: Federal Funding Agencies

• Phase III Study of Daratumumab/rHuPH20 (NSC- 810307) + Lenalidomide or Lenalidomide as Post-Autologous Stem Cell Transplant Maintenance Therapy in Patients with Multiple Myeloma (MM) Using Minimal Residual Disease to Direct Therapy Duration (DRAMMATIC

  Ganguly, S. (PI)

  6/27/19 → 6/26/29

  Project: Non Profit

• Multicenter, Registry Study of Avance® Nerve Graft Utilization, Evaluations and Outcomes in Peripheral Nerve Injury Repair

  Ellsworth, IV, W. A. (PI) & Albright, S. (Key Personnel)

  6/14/19 → …

  Project: Clinical Trial

• Edwards PASCAL CLASP IID/IIF Pivotal Clinical Trial (CLASP IID/IIF)

  Kleiman, N. (PI), Faza, N. (Key Personnel), Goel, S. (Key Personnel), Guha, A. (Key Personnel), Kassi, M. (Key Personnel), Lawrie, G. M. (Key Personnel), Little, S. H. (Key Personnel), Reardon, M. J. (Key Personnel) & Yousefzai, R. (Key Personnel)

  6/11/19 → …

  Project: Clinical Trial

• Study ROR-PH-303, ADVANCE EXTENSION, is an open-label extension (OLE) study for participants with WHO Group 1 PAH who have participated in another Phase 2 or Phase 3 study of ralinepag

  Safdar, Z. (PI), Sahay, S. (Key Personnel) & Syed, M. U. (Key Personnel)

  5/17/19 → …

  Project: Clinical Trial

• Neuromuscular Observational Research (MOVR) Data Hub Protocol

  Greene, E. P. (PI), Appel, S. H. (Key Personnel) & Shroff, S. (Key Personnel)

  5/17/19 → …

  Project: Clinical Trial

• A Phase III, Long-Term, Randomized, Double-blind, Placebo-controlled Trial of Troriluzole in Adult Subjects With Spinocerebellar Ataxia.

  Billnitzer, A. (PI)

  5/10/19 → …

  Project: Clinical Trial

• Daratumab to Enhance therapeutic Effectiveness of Revlimid in Smoldering Myeloma (DETER-SMM)

  Ganguly, S. (PI)

  4/30/19 → 4/29/29

  Project: Non Profit

• A prospective, multi-center, observational study of the safety, tolerability and effectiveness of SPINRAZA in adult patients with Spinal Muscular Atrophy

  Greene, E. P. (CoI) & Shroff, S. (CoI)

  4/26/19 → 4/25/44

  Project: Non Profit

• A Multicenter, Registry Study of Avance® Nerve Graft Utilization, Evaluations and Outcomes in Peripheral Nerve Injury Repair

  Spiegel, A. (PI)

  3/21/19 → …

  Project: Clinical Trial

• Study ROR-PH-301, ADVANCE OUTCOMES, is designed to assess the efficacy and safety of ralinepag when added to pulmonary arterial hypertension standard of care or PAH-specific background therapy in subjects with World Health Organization Group 1 PAH

  Safdar, Z. (PI), Sahay, S. (Key Personnel) & Syed, M. U. (Key Personnel)

  3/21/19 → …

  Project: Clinical Trial

• NRG-BR004: A Randomized, Double-Blind, Phase III Trial of Paclitaxel/Trastuzumab/Pertuzumab with Atezolizumab or Placebo in First-Line HER2-Positive Metastatic Breast Cancer

  Geyer, C. E. (PI), Niravath, P. A. (PI), Chang, J. C. (CoI) & Darcourt, J. (CoI)

  3/12/19 → 2/28/25

  Project: Non Profit

• A Phase III Randomized, Placebo-Controlled Study of Pembrolizumab (MK-3475, NSC #776864)) in addition to Paclitaxel and Carboplatin for Measurable Stage III or IVA, Stage IVB or Recurrent Endometrial Cancer

  Kamat, A. A. (PI), Darcourt, J. (CoI), Singh, M. (CoI), Suri, A. (CoI) & Zaid, T. (CoI)

  3/1/19 → 2/28/25

  Project: Non Profit

• EA5163/S1709 INSIGNA: A Randomized, Phase III Study of Firstline Immunotherapy alone or in Combination with Chemotherapy in Induction/Maintenance or Postprogression in Advanced Nonsquamous Non¿Small Cell Lung Cancer (NSCLC) with Immunobiomarker SIGNature

  Bernicker, E. H. (CoI), Darcourt, J. (CoI) & Zhang, J. (CoI)

  2/28/19 → 2/27/44

  Project: Non Profit

• Resubmission_R01_Subcontract_MD Anderson-Early Detection of Hepatocellular Carcinoma

  Victor, III, D. W. (PI)

  2/19/19 → …

  Project: Clinical Trial

• Circulating tumor DNA 5-hydroxymethylcytosine as a novel biomarker for cancers.

  Li, Z. (PI), Abdelrahim, M. (Key Personnel), Chang, J. C. (Key Personnel), Darcourt, J. (Key Personnel), Pingali, S. R. (Key Personnel), Sahay, S. (Key Personnel), Shah, S. (Key Personnel), Singh, M. (Key Personnel), Zhang, J. (Key Personnel), Zhou, S. (Key Personnel) & Zu, Y. (Key Personnel)

  1/10/19 → …

  Project: Clinical Trial

• Effects of epidural and transcutaneous spinal stimulation

  Sayenko, D. (PI), Barber, S. (Key Personnel), Britz, G. W. (Key Personnel), Horner, P. J. (Key Personnel), Kaldis, T. (Key Personnel), Karmonik, C. (Key Personnel) & Villapol, S. (Key Personnel)

  9/27/18 → …

  Project: Clinical Trial

• Prevention of De Novo HCV with Antiviral HCV Therapy Post-Liver and Post-Kidney Transplant

  Ghobrial, R. M. (PI)

  9/18/18 → 9/17/43

  Project: Non Profit

• Idiopathic Pulmonary Fibrosis and Interstitial Lung Disease Prospective Outcomes Registry (IPF/ILD-PRO)

  Safdar, Z. (PI), Huang, H. J. (Key Personnel), Sahay, S. (Key Personnel) & Syed, M. U. (Key Personnel)

  8/2/18 → …

  Project: Clinical Trial

• QoL after bladder surgery in neurogenic bladder patients

  Khavari, R. (PI) & Boone, T. B. (Key Personnel)

  6/28/18 → …

  Project: Clinical Trial

• Mechanism of Intratumoral Transport of Particulate Drugs

  Chen, S.-H. (PI)

  6/15/18 → 8/31/25

  Project: Federal Funding Agencies

• TAILOR RT: A RANDOMIZED TRIAL OF REGIONAL RADIOTHERAPY IN BIOMARKER LOW RISK NODE POSITIVE AND T3N0 BREAST CANCER

  Teh, B. S. (PI), Chang, J. C. (CoI), Farach, A. M. (CoI), Haque, W. M. (CoI), Morgan, P. B. (CoI), Niravath, P. A. (CoI), Shadle, K. M. (CoI), Shkedy, C. (CoI) & Singh, M. (CoI)

  5/30/18 → 5/29/28

  Project: Non Profit

• IMAG-MRI Based Calf Muscle Perfusion To Assess Patients with Symptomatic PAD

  Shah, D. J. (PI), Le, L. (Key Personnel), Lumsden, A. B. (Key Personnel), Nabi, F. (Key Personnel), Peden, E. K. (Key Personnel) & Rahimi, M. (Key Personnel)

  4/20/18 → …

  Project: Clinical Trial

• Corrona Inflammatory Bowel Disease (IBD) Registry

  Abraham, B. P. (PI) & Fan, C. (Key Personnel)

  4/3/18 → …

  Project: Clinical Trial

• A phase III, multicenter, randomized, study of atezolizumab/placebo administered in combination with paclitaxel, carboplatin, and bevacizumab to patients with newly-diagnosed stage III or stage IV ovarian, fallopian tube, or primary peritoneal cancer

  Kamat, A. A. (PI), Alaniz, A. (CoI), Bernicker, E. H. (CoI), Darcourt, J. (CoI), Heyne, K. (CoI), Singh, M. (CoI), Suri, A. (CoI) & Zaid, T. (CoI)

  3/13/18 → 3/12/43

  Project: Non Profit

• Transcatheter Mitral Valve Replacement With the Medtronic Intrepid TMVR System in Patients With Severe Symptomatic Mitral Regurgitation. (APOLLO)

  Kleiman, N. (PI), Ahsan, S. A. (Key Personnel), Chang, S.-M. (Key Personnel), Faza, N. (Key Personnel), Goel, S. (Key Personnel), Hussain, I. (Key Personnel), Kim, J. H. (Key Personnel), Little, S. H. (Key Personnel), Nabi, F. (Key Personnel), Reardon, M. J. (Key Personnel) & Yousefzai, R. (Key Personnel)

  2/13/18 → …

  Project: Clinical Trial

• Role of Brain Inflammation in Alzheimer’s Disease

  Masdeu, J. C. (PI), Faridar, A. (Key Personnel), Nakawah, M. O. (Key Personnel) & Pascual, B. (Key Personnel)

  2/7/18 → …

  Project: Clinical Trial

• Phase I-II Study Evaluating HSV-tk + Valacyclovir Gene Therapy

  Baskin, D. S. (PI), Butler, E. B. (Key Personnel) & Teh, B. S. (Key Personnel)

  1/15/18 → …

  Project: Clinical Trial

• Clinical Research Consortium for Spinocerebellar Ataxias (CRC-SCA) to Study Natural History Study of and Genetic Modifiers in Spinocerebellar Ataxias (SCA)

  Billnitzer, A. (PI)

  12/15/17 → …

  Project: Clinical Trial

• Modulation of tumor inflammatory factor for immune therapy

  Chen, S.-H. (PI) & Pan, P.-Y. (Project Director)

  9/22/17 → 8/31/25

  Project: Federal Funding Agencies

• LONGITUDINAL EARLY ONSET ALZHEIMERâ??S DISEASE (LEADS)

  Masdeu, J. C. (PI), Faridar, A. (CoI), Nakawah, M. O. (CoI) & Pascual, B. (CoI)

  9/15/17 → 5/31/25

  Project: Non Profit

• Phase I-II Study Evaluating HSV-tk + Valacyclovir Gene Therapy Combination with Radiotherapy and Chemotherapy for Recurrent Glioblastoma Multiforme

  Baskin, D. S. (PI), Butler, E. B. (Key Personnel) & Teh, B. S. (Key Personnel)

  8/23/17 → …

  Project: Clinical Trial

• Learning-Based Approach for Personalized Craniomaxillofacial Surgical Planning

  Gateno, J. (PI), Alfi, D. (Key Personnel) & Fung, S. H. (Key Personnel)

  7/1/17 → 6/30/25

  Project: Federal Funding Agencies

• Natural History and Biospecimen Repository for Dystonia

  Ondo, W. G. (PI)

  6/30/17 → …

  Project: Clinical Trial

• Development of therapeutic mRNA vaccine

  6/28/17 → 6/28/27

  Project: Non Profit

• PHASE III, RANDOMIZED, DOUBLE-BLIND, PLACEBO- CONTROLLED, PARALLEL-GROUP, STUDY OF AB103 AS COMPARED TO PLACEBO IN PATIENTS WITH NECROTIZING SOFT TISSUE INFECTIONS (NSTI)

  Dhala, A. (CoI), Martinez, S. (CoI), Mobley, C. M. (CoI) & Ochoa, R. A. (CoI)

  6/20/17 → 6/19/42

  Project: Federal Funding Agencies

• National Ataxia Foundation (NAF) - Clinical Research Consortium for the Study of Cerebellar Ataxias

  Ashizawa, T. (PI)

  6/16/17 → 12/31/24

  Project: Non Profit

• A Double-blind, Randomized, Controlled Dose Escalation Trial of Autologous Mesenchymal Stromal Cells in Living Donor Kidney Transplant Recipients

  Gaber, A. O. (PI), Knight, R. J. (Key Personnel), Moore, L. W. (Key Personnel) & Sabek, O. (Key Personnel)

  5/15/17 → …

  Project: Clinical Trial

• Carotid Revascularization and Medical Management for Asymptomatic Carotid stenosis - Hemodynamics (CREST-H)

  Chiu, D. (PI), Gadhia, R. R. (CoI), Misra, V. (CoI) & Volpi, J. J. (CoI)

  5/15/17 → 7/31/27

  Project: Federal Funding Agencies

• NSABP B-51 A Randomized Phase III Clinical Trial Evaluating Post-Mastectomy Chestwall and Regional Nodal XRT and Post-Lumpectomy Regional Nodal XRT in Patients with Positive Axillary

  12/9/16 → 12/9/41

  Project: Non Profit

• A RANDOMIZED PHASE III DOUBLE BLINDED PLACEBO CONTROLLED TRIAL OFASPIRIN AS ADJUVANT THERAPY FOR HER2 NEGATIVE BREAST CANCER: THE ABCTRIAL

  Arentz, C. (PI), Abdelrahim, M. (CoI), Bernicker, E. H. (CoI), Chang, J. C. (CoI), Heyne, K. (CoI), Niravath, P. A. (CoI), Singh, M. (CoI) & Zhang, J. (CoI)

  12/8/16 → 12/7/41

  Project: Non Profit

• NMDA Receptor in Psychosis: Specific Auto-Antibodies

  Masdeu, J. C. (PI), Faridar, A. (Key Personnel), Nakawah, M. O. (Key Personnel), Pascual, B. (Key Personnel) & Toledo, J. B. (Key Personnel)

  11/14/16 → …

  Project: Clinical Trial

• IMAG-The MITRAREVERSE Study

  Shah, D. J. (PI), Faza, N. (Key Personnel), Little, S. H. (Key Personnel) & Nabi, F. (Key Personnel)

  10/24/16 → …

  Project: Clinical Trial

• EAY131 - Molecular Analysis for Therapy Choice (MATCH)

  Bernicker, E. H. (PI), Chang, J. C. (CoI), Darcourt, J. (CoI), Heyne, K. (CoI), Kamat, A. A. (CoI), Pingali, S. R. (CoI) & Singh, M. (CoI)

  9/20/16 → 9/20/41

  Project: Federal Funding Agencies

• Neuroimaging in AD

  Masdeu, J. C. (PI), Faridar, A. (Key Personnel), Karmonik, C. (Key Personnel), Nakawah, M. O. (Key Personnel), Pascual, B. (Key Personnel), Roman, G. C. (Key Personnel) & Toledo, J. B. (Key Personnel)

  9/15/16 → …

  Project: Clinical Trial

• Imaging Dementia-Evidence for Amyloid Scanning (IDEAS) Study

  Masdeu, J. C. (PI)

  7/14/16 → 7/13/41

  Project: Non Profit

• MRI Prognosis Study

  Shah, D. J. (PI), Chamsi-Pasha, M. A. (Key Personnel), El-Tallawi, C. (Key Personnel), Faza, N. (Key Personnel), Graviss, E. A. (Key Personnel), Malahfji, M. (Key Personnel), Nabi, F. (Key Personnel) & Nagueh, S. (Key Personnel)

  6/14/16 → …

  Project: Clinical Trial

• PBR28 PET

  Masdeu, J. C. (PI), Appel, S. H. (Key Personnel), Faridar, A. (Key Personnel), Karmonik, C. (Key Personnel), Nakawah, M. O. (Key Personnel) & Pascual, B. (Key Personnel)

  6/7/16 → …

  Project: Clinical Trial

• Long-Term Nicotine Treatment of Mild Cognitive Treatment

  Masdeu, J. C. (PI) & Pascual, B. (CoI)

  6/1/16 → 1/31/25

  Project: Federal Funding Agencies