Houston Methodist

Projects

Projects per year 2000 2016 2018 2019 2020 2021 2022 2023 2024 2046

• 193 Not started
• 541 Active
• 826 Finished

Projects per year

Search results

• Active

  Glutathione, Brain Metabolism and Inflammation in Alzheimer's Disease

  Masdeu, J. C. (PI)

  9/30/20 → 4/30/25

  Project: Federal Funding Agencies

• Spatiotemporal modeling of cancer-niche interactions in breast cancer bone metastasis

  Wong, S. T. (PI), Chang, J. C. (Key Personnel) & Sheng, J. (Key Personnel)

  9/15/20 → 8/31/25

  Project: Federal Funding Agencies

• Age-related TDP-43 neuropathology: using disease-driving mechanisms to guide classification

  Cykowski, M. D. (PI)

  9/15/20 → 3/31/25

  Project: Federal Funding Agencies

• CPRIT RNA Therapeutics Core

  Cooke, J. P. (PI), Godin, B. (Key Personnel) & Kiss, D. L. (Key Personnel)

  8/31/20 → 8/30/25

  Project: State

• HF - preCardia System EFS for Treatment of ADHF preCardia, Inc.

  Yousefzai, R. (PI), Ahsan, S. A. (Key Personnel), Bhimaraj, A. (Key Personnel), Goel, S. (Key Personnel), Gorthi, J. R. (Key Personnel), Guha, A. (Key Personnel), Hussain, I. (Key Personnel), Kassi, M. (Key Personnel), Kim, J. H. (Key Personnel) & Suarez, E. E. (Key Personnel)

  8/28/20 → …

  Project: Clinical Trial

• Elucidating spinal sensorimotor network components that underlie recovery of motor functions via lumbosacral epidural electrical stimulation in humans with spinal cord injury

  Sayenko, D. (PI)

  8/15/20 → 7/31/25

  Project: Federal Funding Agencies

• Understanding the mechanisms that regulate cytoplasmic capping and defining its contributions to post-transcriptional gene regulation

  Kiss, D. L. (PI)

  8/15/20 → 6/30/25

  Project: Federal Funding Agencies

• A Study of Biological Markers for the Nervous and Immune Systems and Free Radical Mediated Processes in Amyotrophic Lateral Sclerosis (ALS)

  Appel, S. H. (PI), Beers, D. (Key Personnel), Greene, E. P. (Key Personnel), Lai, E. C. (Key Personnel), Liao, B. (Key Personnel), Shroff, S. (Key Personnel) & Zhao, W. (Key Personnel)

  8/13/20 → …

  Project: Clinical Trial

• Neuro-Afib Study

  Gadhia, R. R. (PI), Garg, T. (Key Personnel) & Hodics, T. M. (Key Personnel)

  8/6/20 → …

  Project: Clinical Trial

• Outcome-Driven Approach to Minimize the Risks of Facial Distortion Following CMF Surgery

  Gateno, J. (PI)

  8/1/20 → 7/31/26

  Project: Federal Funding Agencies

• Systematic identification of astrocyte-tumor crosstalk regulating brain metastatic tumors

  Wong, S. T. (PI), Zhao, H. (PI) & Sheng, J. (Key Personnel)

  8/1/20 → 1/31/25

  Project: Federal Funding Agencies

• HEALEY ALS Platform Trial - Regimen-Specific Appendix C - For CNM-Au8

  Appel, S. H. (PI), Shroff, S. (PI), Greene, E. P. (CoI) & Liao, B. (CoI)

  7/24/20 → 7/23/25

  Project: Non Profit

• Massachusetts General Hospital Healey Center for ALS - Healey ALS Platform Trial

  Appel, S. H. (PI), Shroff, S. (PI) & Greene, E. P. (CoI)

  7/24/20 → 7/23/25

  Project: Non Profit

• HEALEY ALS Platform Trial - Regimen-Specific Appendix E - For SLS-005, also known as Trehalose injection, 90.5 mg/mL for intravenous infusion.

  Shroff, S. (PI)

  7/24/20 → 7/23/25

  Project: Non Profit

• HEALEY ALS Platform Trial - Regimen-Specific Appendix B - For verdiperstat (also known as BHV-3241)

  Appel, S. H. (PI), Shroff, S. (PI), Greene, E. P. (CoI) & Liao, B. (CoI)

  7/24/20 → 7/23/25

  Project: Non Profit

• HEALEY ALS Platform Trial - Regimen-Specific Appendix A - For 0.3mh/kg SC zilucoplan administered once daily and placebo

  Appel, S. H. (PI), Shroff, S. (PI), Greene, E. P. (CoI) & Liao, B. (CoI)

  7/24/20 → 7/23/25

  Project: Non Profit

• Neuro-Afib Study - Retrospective Phase (Phase I)

  Gadhia, R. R. (PI) & Garg, T. (CoI)

  7/13/20 → 7/12/45

  Project: Non Profit

• Evaluation of the Portico¿ NG Transcatheter Aortic Valve in High and Extreme Risk Patients with Symptomatic Severe Aortic Stenosis (ABT-CIP-10297)

  Kleiman, N. (PI), Gadhia, R. R. (CoI), Garg, T. (CoI), Goel, S. (CoI), Reardon, M. J. (CoI) & Volpi, J. J. (CoI)

  7/6/20 → 7/5/45

  Project: Non Profit

• A Novel Non-Invasive Approach for Regaining Self-Assisted Standing after Spinal Cord Injury: Combining Transcutaneous Spinal Stimulation and Functional Electrical Stimulation

  Sayenko, D. (PI)

  7/1/20 → 6/30/25

  Project: Non Profit

• Systems-wide analysis of oxidative stress-responsive m6A epitranscriptome

  Weng, Y.-L. (PI) & Krencik, R. C. (Key Personnel)

  6/15/20 → 3/31/26

  Project: Federal Funding Agencies

• Influence of pre-analytical factors in glioblastoma MGMT promoter methylation biomarker assay

  Rostomily, R. C. (PI), Mitra, S. (Key Personnel) & Powell, S.Z.-E. (Key Personnel)

  6/1/20 → 5/31/25

  Project: Federal Funding Agencies

• LONGITUDINAL EARLY ONSET ALZHEIMER¿S DISEASE (LEADS) supplement

  Masdeu, J. C. (PI)

  6/1/20 → 5/31/25

  Project: Federal Funding Agencies

• Convergent AI for Precise Breast Cancer Risk Assessment

  Wong, S. T. (PI), Chang, J. C. (Key Personnel) & Ensor, Jr., J. E. (Key Personnel)

  6/1/20 → 5/31/25

  Project: Federal Funding Agencies

• Prospective Sudden Cardiac Death Risk Stratification Using Cardiac MRI and Echocardiography Machine Learning in Mitral Valve Prolapse.

  Shah, D. J. (PI)

  5/26/20 → 4/30/25

  Project: Federal Funding Agencies

• Registry for Neurological Endpoint Assessments among patients with Ischemic and Hemorrhagic Stroke (REINAH)

  Britz, G. W. (Key Personnel), Horner, P. J. (Key Personnel), Misra, V. (Key Personnel) & Vahidy, F. S. (Key Personnel)

  4/28/20 → …

  Project: Clinical Trial

• Voice Rest Adherence After Phonomicrosurgery

  Yiu, Y. (PI)

  4/20/20 → 3/31/25

  Project: Federal Funding Agencies

• Defining the altered FUS-PARP-1-DNA Ligase III axis and its implications to nuclear and mitochondrial genome damage response in Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD)

  Hegde, M. (PI), Hamilton, D. J. (Key Personnel), Horner, P. J. (Key Personnel) & Mitra, J. (Key Personnel)

  4/15/20 → 3/31/25

  Project: Federal Funding Agencies

• Sample and Data Collection for Houston Methodist Cancer Center Research

  Chang, J. C. (PI), Bernicker, E. H. (Key Personnel), Darcourt, J. (Key Personnel), Heyne, K. (Key Personnel), Niravath, P. A. (Key Personnel) & Singh, M. (Key Personnel)

  4/9/20 → …

  Project: Clinical Trial

• U.S. Study to Protect Brain Health through Lifestyle Intervention to Reduce Risk:Neuroimaging Ancillary Study

  Masdeu, J. C. (PI)

  4/1/20 → 3/31/25

  Project: Federal Funding Agencies

• Novel carbon nanozyme mechanisms for traumatic brain injury therapy

  Hegde, M. (PI)

  4/1/20 → 3/31/25

  Project: Federal Funding Agencies

• Myotonic Dystrophy Compilation of Clinical Findings

  Greene, E. P. (PI), Appel, S. H. (Key Personnel), Ashizawa, T. (Key Personnel), Mathuria, N. (Key Personnel) & Shroff, S. (Key Personnel)

  4/1/20 → …

  Project: Clinical Trial

• A Pilot Randomized Controlled Trial of De Novo Belatacept-Based Immunosuppression in Lung Transplantation

  Huang, H. J. (PI)

  3/26/20 → 3/25/45

  Project: Non Profit

• Exercise Intervention for Strong and Fit Pediatric Fontan Patients (StrongFitFontan)

  Cooke, J. P. (PI)

  3/10/20 → 2/28/25

  Project: Federal Funding Agencies

• CTSU - IRB SUBMISSIONA Phase III Trial To Evaluate The Efficacy Of The Addition Of Inotuzumab Ozogamicin (A Conjugated Anti-Cd22 Monoclonal Antibody) To Frontline Therapy In Young Adults (Ages 18-39 Years) With Newly Diagnosed Precursor B-Cell ALL.

  Abdelrahim, M. (CoI), Bernicker, E. H. (CoI), Chang, J. C. (CoI), Heyne, K. (CoI), Niravath, P. A. (CoI), Singh, M. (CoI) & Zhang, J. (CoI)

  3/6/20 → 3/5/45

  Project: Non Profit

• ALLIANCE A221602: OLANZAPINEWITH ORWITHOUT FOSAPREPITANT FOR THE PREVENTION OF CHEMOTHERAPY INDUCED NAUSEA AND VOMITING (CINV) IN PATIENTS RECEIVING HIGHLY EMETOGENIC CHEMOTHERAPY (HEC): A PHASE III RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL

  Darcourt, J. (PI), Bernicker, E. H. (CoI), Chang, J. C. (CoI), Geyer, C. E. (CoI), Heyne, K. (CoI) & Niravath, P. A. (CoI)

  3/6/20 → 3/5/45

  Project: Non Profit

• The COMPASSHER2 Trials (COMprehensive Use of Pathologic Response ASSessment to Optimize Therapy in HER2-Positive Breast Cancer): COMPASSHER2 Residual Disease (RD), A Double-Blinded, Phase III Randomized Trial of T-DM1 and Placebo Compared with T-DM1 and

  3/6/20 → 3/5/45

  Project: Non Profit

• INTEGRATION OF IMMUNOTHERAPY INTO ADJUVANT THERAPY FOR RESECTED NSCLC: ALCHEMIST CHEMO-IO (ACCIO)

  Bernicker, E. H. (PI) & Zhang, J. (PI)

  3/6/20 → 3/5/45

  Project: Non Profit

• Imaging the mechanical microenvironment in cancers using ultrasound

  Chua, C. Y. X. (PI) & Chang, J. C. (Key Personnel)

  3/1/20 → 2/28/25

  Project: Federal Funding Agencies

• Molecular mechanism of streptococcal adaptation to host nutritional defenses

  Kumaraswami, M. (PI) & Olsen, R. J. (Key Personnel)

  2/25/20 → 1/31/26

  Project: Federal Funding Agencies

• Ocrelizumab for Psychosis by Autoimmunity (OPA)

  Masdeu, J. C. (PI), Faridar, A. (Key Personnel), Madan, A. (Key Personnel), Nakawah, M. O. (Key Personnel), Pascual, B. (Key Personnel), Toledo, J. B. (Key Personnel) & Weinstein, B. (Key Personnel)

  2/20/20 → …

  Project: Clinical Trial

• Biophysical roles of pre-metastatic niche evolution on transport of circulating tumor cells

  Liu, X. (PI) & Qin, L. (PI)

  2/15/20 → 1/31/26

  Project: Federal Funding Agencies

• Systematic identification of astrocyte-tumor crosstalk regulating brain metastatic tumors

  Wong, S. T. (PI), Zhao, H. (PI), Rostomily, R. C. (Key Personnel) & Sheng, J. (Key Personnel)

  2/15/20 → 1/31/25

  Project: Federal Funding Agencies

• Assessing CSF flow in glymphatics

  Britz, G. W. (PI), Golanov, E. V. (Key Personnel) & Karmonik, C. (Key Personnel)

  2/5/20 → …

  Project: Clinical Trial

• AOCT - Zephyr Valve Registry ZEVR

  Kopas, L. (PI)

  2/3/20 → …

  Project: Clinical Trial

• REDUCE PAS

  Lin, C. H. (PI), Chiu, D. (Key Personnel), Duarte, V. (Key Personnel), Gadhia, R. R. (Key Personnel), Garg, T. (Key Personnel), Kleiman, N. (Key Personnel), Misra, V. (Key Personnel) & Volpi, J. J. (Key Personnel)

  1/28/20 → …

  Project: Clinical Trial

• Chart Review Study Leucovorin 5-FULV

  Abdelrahim, M. (PI)

  1/15/20 → …

  Project: Clinical Trial

• A Phase 2, Randomized, Placebo-Controlled Study to Evaluate Fingolimod for the Abrogation of Interstitial Fibrosis and Tubular Atrophy Following Kidney Transplantation

  Gaber, A. O. (PI), Ghobrial, R. M. (Key Personnel), Graviss, E. A. (Key Personnel), Hobeika, M. J. (Key Personnel), Kloc, M. (Key Personnel), Knight, R. J. (Key Personnel), Moore, L. W. (Key Personnel), Rizk, E. (Key Personnel) & Yi, S. (Key Personnel)

  1/13/20 → …

  Project: Clinical Trial

• Randomized sham-control trial to evaluate the effects of Transcutaneous Tibial Nerve Stimulation for Spinal Cord Injury Neurogenic Bladder

  Khavari, R. (PI)

  11/30/19 → 4/29/26

  Project: Federal Funding Agencies

• Association of LVAD inflow cannula position with the development of acquired VWD and altered angiogenesis

  Kassi, M. (PI), Bhimaraj, A. (Key Personnel), Graviss, E. A. (Key Personnel), Guha, A. (Key Personnel), Hussain, I. (Key Personnel), Kim, J. H. (Key Personnel), Martin, C. M. (Key Personnel) & Youker, K. A. (Key Personnel)

  10/30/19 → …

  Project: Clinical Trial

• 18F-MK-6240 Tau PET and Brain Inflammation in Alzheimer’s Disease

  Masdeu, J. C. (PI), Faridar, A. (Key Personnel), Nakawah, M. O. (Key Personnel), Pascual, B. (Key Personnel) & Roman, G. C. (Key Personnel)

  10/29/19 → …

  Project: Clinical Trial