Houston Methodist

Projects

Projects per year 2000 2016 2018 2019 2020 2021 2022 2023 2024 2046

• 193 Not started
• 541 Active
• 826 Finished

Projects per year

Search results

• Active

  Methods and devices to assist and improve cerebrospinal fluid drainage

  Britz, G. W. (PI)

  7/1/22 → 6/30/25

  Project: Federal Funding Agencies

• Combining Transcutaneous Spinal Stimulation and Exoskeleton Training in the Rehabilitation of Spinal Cord Injury.

  Sayenko, D. (PI), Kaldis, T. (Key Personnel) & Tabatabai, L. S. (Key Personnel)

  6/20/22 → …

  Project: Clinical Trial

• A PHASE III, RANDOMIZED, OPEN-LABEL, MULTICENTER STUDY EVALUATING THE EFFICACY AND SAFETY OF ADJUVANT GIREDESTRANT COMPARED WITH PHYSICIAN's CHOICE OF ADJUVANT ENDOCRINE MONOTHERAPY IN PATIENTS WITH ESTROGEN RECEPTOR-?ITIVE, HER2-NEGATIVE

  6/14/22 → 6/13/32

  Project: Non Profit

• A phase II multi-center trial evaluating dual targeting of the PI3K/AKT and NOS pathways for treating metaplastic breast cancer (MpBC)

  Chang, J. C. (PI)

  6/10/22 → 5/31/27

  Project: Federal Funding Agencies

• Understanding the mechanisms that regulate cytoplasmic capping and defining its contributions to post-transcriptional gene regulation (Same as parent grant)

  Kiss, D. L. (PI)

  6/1/22 → 6/30/25

  Project: Federal Funding Agencies

• Ultra-long Acting Transcutaneously Refillable Islatravir Nanofluidic Implant for HIV Pre-Exposure

  Grattoni, A. (PI)

  6/1/22 → 5/31/27

  Project: Federal Funding Agencies

• VENOUS: A translational study of enterococcal bacteremia

  Arias, C. A. (PI)

  6/1/22 → 5/31/25

  Project: Federal Funding Agencies

• Biomarker development in patients with HNPP

  Li, J. (PI)

  6/1/22 → 12/31/25

  Project: Federal Funding Agencies

• Imaging for Precision Medicine in Alzheimer's Disease and Related Disorders

  Masdeu, J. C. (PI), Faridar, A. (Key Personnel), Karmonik, C. (Key Personnel), Nakawah, M. O. (Key Personnel), Pascual, B. (Key Personnel) & Roman, G. C. (Key Personnel)

  5/25/22 → …

  Project: Clinical Trial

• A Phase IIa randomized, double-blind, placebo-controlled study of the effects of L-serine on Mild Cognitive Impairment (MCI)

  Roman, G. C. (PI)

  5/23/22 → 5/22/26

  Project: Non Profit

• CY 6022-Open-Label Study of CK-3773274 for Patients with oHCM Cytokinetics

  Nagueh, S. (PI), Buergler, J. (Key Personnel), El-Tallawi, C. (Key Personnel), Kurrelmeyer, K. M. (Key Personnel) & Nabi, F. (Key Personnel)

  5/19/22 → …

  Project: Clinical Trial

• A randomized, double-blind, placebo-controlled, multicenter, Phase 3 study evaluating long-term efficacy and safety of lanifibranor in adult patients with non-cirrhotic non-alcoholic steatohepatitis (NASH) and fibrosis 2/fibrosis 3 stage of liver fibrosis

  Victor, III, D. W. (PI) & Kodali, S. (Key Personnel)

  5/16/22 → …

  Project: Clinical Trial

• Mechanisms driving cardiac dysfunction in Autosomal Dominant Polycystic Kidney Disease

  Altamirano, F. (PI)

  5/15/22 → 4/30/27

  Project: Federal Funding Agencies

• Exploring the role of estrogen receptor beta in progression and metastasis of Inflammatory breast cancer

  Thomas, C. (PI)

  5/1/22 → 11/30/25

  Project: Federal Funding Agencies

• A PHASE III, MULTICENTER, RANDOMIZED, OPEN LABEL STUDY OF ATEZOLIZUMAB (ANTI PD-L1 ANTIBODY) PLUS BEVACIZUMAB VERSUS ACTIVE SURVEILLANCE AS ADJUVANT THERAPY IN PATIENTS WITH HEPATOCELLULAR CARCINOMA

  Abdelrahim, M. (PI)

  4/24/22 → 4/23/32

  Project: Non Profit

• Early Detection of Hepatocellular Carcinoma - Renewal Submission

  Victor, III, D. W. (PI)

  4/21/22 → 2/28/27

  Project: Federal Funding Agencies

• Defining cellular mechanisms of chronic graft failure in transplanted hearts with single cell multi-omics

  Bhimaraj, A. (PI)

  4/20/22 → 3/31/26

  Project: Federal Funding Agencies

• Photoacoustic Imaging to Guide Catheter Ablation of Cardiac Arrhythmias

  Mathuria, N. (PI)

  4/18/22 → 3/31/25

  Project: Federal Funding Agencies

• OCS Liver Perfusion (OLP) Post-Approval Registry Protocol

  Hobeika, M. J. (PI) & Mobley, C. M. (Key Personnel)

  4/9/22 → …

  Project: Clinical Trial

• XBP1 Inhibition and STING activation for the treatment of cancer

  Hu, C.-C. A. (PI)

  4/8/22 → 3/31/27

  Project: Federal Funding Agencies

• CONNECT-AV Post-Market Surveillance of WavelinQ EndoAVF System BD Bard

  Le, L. (PI) & Peden, E. K. (Key Personnel)

  4/4/22 → …

  Project: Clinical Trial

• Molecular basis of decreased susceptibility to beta-lactam antibiotics in Streptococcus pyogenes

  Musser, J. M. (PI)

  3/24/22 → 2/28/25

  Project: Federal Funding Agencies

• The Unique Roles of Tumor-Specific Th9 Cells for Solid Tumor Eradication

  Lu, Y. (PI)

  3/1/22 → 2/28/26

  Project: Federal Funding Agencies

• A Randomized Trial of Ultrasound-facilitated, Catheter-directed, Thrombolysis Versus Anticoagulation for Acute Intermediate-high Risk Pulmonary Embolism: The Higher-risk Pulmonary Embolism Thrombolysis Study

  Bartra, H. (Key Personnel)

  2/10/22 → …

  Project: Clinical Trial

• Bioenergetic potentiation in Alzheimer's Disease as a therapeutic strategy

  Blanco, E. (PI)

  2/1/22 → 1/31/25

  Project: Non Profit

• P38 MAPK is a molecular switch that controls the acquired resistance in adoptive cell therapy

  Lu, Y. (PI)

  2/1/22 → 5/31/25

  Project: Federal Funding Agencies

• Systematic identification of astrocyte-tumor crosstalk regulating brain metastatic tumors

  Zhao, H. (PI)

  2/1/22 → 1/31/25

  Project: Federal Funding Agencies

• A Phase II Clinical tRial of neoADjuVant sAsanlimab and stereotaCtiC body radIatioN thErapy as an in situ vaccine for cisplatin-ineligible Muscle Invasive Bladder Cancer (RAD VACCINE MIBC)

  Satkunasivam, R. (PI), Butler, E. B. (Key Personnel), Chan, K. S. (Key Personnel), Chen, S.-H. (Key Personnel), Esnaola, N. F. (Key Personnel), Farach, A. M. (Key Personnel), Teh, B. S. (Key Personnel) & Zhang, J. (Key Personnel)

  1/20/22 → …

  Project: Clinical Trial

• A multi-center, randomized, 36-month, parallel group, non-inferiority, phase III study to compare the effectiveness of 500 mcg QD or alternate regimen of roflumilast (Daliresp) therapy versus 250 mg QD, 500 mg QD three times per week, or alternate regime

  Folz, R. J. (PI)

  12/1/21 → 5/31/25

  Project: Federal Funding Agencies

• Scalable, high-resolution mapping of RNA-protein interaction networks that drive breast cancer progression and plasticity

  Brannan, K. W. (PI)

  12/1/21 → 11/30/26

  Project: State

• Inhibition of Oral Tumorigenesis by Antitumor B

  You, M. (PI)

  12/1/21 → 5/31/25

  Project: Federal Funding Agencies

• A multi-center, randomized, 36-month, parallel group, non-inferiority, phase III study to compare the effectiveness of 500 mcg QD or alternate regimen of roflumilast (Daliresp) therapy versus 250 mg QD, 500 mg QD three times per week, or alternate regime

  Folz, R. J. (PI)

  12/1/21 → 5/31/25

  Project: Federal Funding Agencies

• Harnessing neuroplasticity of postural sensorimotor networks using non-invasive spinal neuromodulation to maximize functional recovery after spinal cord injury

  Sayenko, D. (PI), Barber, S. (Key Personnel), Horner, P. J. (Key Personnel), Kaldis, T. (Key Personnel) & Vahidy, F. S. (Key Personnel)

  12/1/21 → 8/31/27

  Project: Federal Funding Agencies

• A Study to Perform Apheresis (Leukapheresis) on Patients with Amyotrophic Lateral Sclerosis to Collect Regulatory T-Lymphocytes (Tregs)

  Shroff, S. (PI)

  11/30/21 → …

  Project: Clinical Trial

• RiOciguAt UseRs Registry The ROAR registry

  Sahay, S. (PI) & Safdar, Z. (Key Personnel)

  11/30/21 → …

  Project: Clinical Trial

• New IDEAS: Imaging Dementia¿Evidence for Amyloid Scanning StudyA Study to Improve Precision in Amyloid PET Coverage and Patient Care

  Masdeu, J. C. (PI), Faridar, A. (CoI), Nakawah, M. O. (CoI), Pascual, B. (CoI) & Roman, G. C. (CoI)

  11/18/21 → 11/17/31

  Project: Non Profit

• A Phase I Trial to Evaluate Safety and Tolerability of Abatacept followed by Subcutaneous Interleukin-2 Administration in Patients with Amyotrophic Lateral Sclerosis

  Shroff, S. (PI)

  11/18/21 → …

  Project: Clinical Trial

• A Clinical Evaluation of the RheOx Bronchial Rheoplasty System for the Treatment of the Symptoms of Chronic Bronchitis in Adult Patients With COPD

  Kopas, L. (PI) & Doerr, C. H. (Key Personnel)

  11/8/21 → …

  Project: Clinical Trial

• RANDOMIZED PHASE II/III TRIAL OF RADIATION WITH CISPLATIN AT 100 MG/M2 EVERY THREE WEEKS VERSUS RADIATION WITH WEEKLY CISPLATIN AT 40 MG/M2 FOR PATIENTS WITH LOCOREGIONALLY ADVANCED SQUAMOUS CELL CARCINOMA OF THE HEAD AND NECK (SCCHN)

  Zhang, J. (PI)

  10/27/21 → 10/26/31

  Project: Non Profit

• Treating Obstructive Sleep Apnea Using Targeted Hypoglossal Neurostimulation

  Takashima, M. (PI) & Ahmed, O. G. (Key Personnel)

  10/21/21 → …

  Project: Clinical Trial

• Upper Extremity Nerve Transfers Grant Transfer Nerve Transfers to Improve Upper Extremity Function and Quality of Life in Tetraplegic Patients

  Faraji, A. (PI)

  10/11/21 → …

  Project: Clinical Trial

• Texas Southern University Breast Cancer Prevention and Screening Center (TSU BCSPC)

  Niravath, P. A. (PI)

  10/1/21 → 2/28/25

  Project: State

• Cardiogenic Shock Working Group Registry

  Kim, J. H. (PI), Ahsan, S. A. (Key Personnel), Bhimaraj, A. (Key Personnel), Fida, N. (Key Personnel), Gorthi, J. R. (Key Personnel), Guha, A. (Key Personnel), Hussain, I. (Key Personnel), Kassi, M. (Key Personnel), Martin, C. M. (Key Personnel) & Yousefzai, R. (Key Personnel)

  10/1/21 → …

  Project: Clinical Trial

• The JenaValve ALIGN-AR Pivotal Trial (ALIGN-AR)

  Reardon, M. J. (PI), Chang, S.-M. (Key Personnel), Faza, N. (Key Personnel), Goel, S. (Key Personnel), Kleiman, N. (Key Personnel) & Little, S. H. (Key Personnel)

  9/29/21 → …

  Project: Clinical Trial

• EF-32 - TRIDENT A Pivotal Randomized, Open-label Study of Optune® (TTFields, 200kHz) Concomitant with Radiation Therapy and Temozolomide for the Treatment of Newly Diagnosed Glioblastoma

  Baskin, D. S. (Key Personnel), Farach, A. M. (Key Personnel), Haque, W. M. (Key Personnel) & Teh, B. S. (Key Personnel)

  9/29/21 → …

  Project: Clinical Trial

• A Novel Multi-Antigen Vaccine (TNBCvax) to Prevent Triple Negative Breast Cancer

  You, M. (PI)

  9/16/21 → 5/15/25

  Project: Federal Funding Agencies

• Gossamer_GB002-2102_Phase 2 OLE_Pulmonary Arterial Hypertension An Open-label Extension Study Evaluating the Long-term Safety and Efficacy of Oral Inhalation of GB002 for the Treatment of WHO Group 1 Pulmonary Arterial Hypertension (PAH)

  Sahay, S. (PI) & Safdar, Z. (Key Personnel)

  9/15/21 → …

  Project: Clinical Trial

• TTVR Early Feasibility Study

  Goel, S. (PI), Ahsan, S. A. (Key Personnel), Chang, S.-M. (Key Personnel), Dave, A. (Key Personnel), Faza, N. (Key Personnel), Kim, J. H. (Key Personnel), Kleiman, N. (Key Personnel), Lador, A. (Key Personnel), Little, S. H. (Key Personnel), Reardon, M. J. (Key Personnel), Schurmann, P. A. (Key Personnel), Valderrábano, M. (Key Personnel) & Yousefzai, R. (Key Personnel)

  9/15/21 → …

  Project: Clinical Trial

• ROSE-LAWN Recovery and Outcome from StrokE-Longitudinal Assessment With Neuroimaging (ROSE-LAWN)

  Britz, G. W. (PI) & Misra, V. (Key Personnel)

  9/15/21 → …

  Project: Clinical Trial

• Targeting Inflammation and Alloimmunity in Lung Transplant Recipients with Clazakizumab

  Huang, H. J. (PI)

  9/14/21 → 6/30/25

  Project: Federal Funding Agencies