Houston Methodist

Projects

Projects per year 2000 2013 2016 2018 2019 2020 2021 2022 2023 2024 2046

• 193 Not started
• 538 Active
• 826 Finished

Projects per year

Search results

• Not started

  TORAX - LINX - RETHINK REFLUX Registry

  Kim, M. P. (PI)

  Project: Clinical Trial

• A151216 - Genetic Testing in Screening Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been or Will Be Removed by Surgery ALCHEMIST

  Zhang, J. (PI), Heyne, K. (Key Personnel) & Singh, M. (Key Personnel)

  Project: Clinical Trial

• Randomized Study of Erlotinib vs Observation in Patients With Completely Resected Epidermal Growth Factor Receptor (EGFR) Mutant Non-small Cell Lung Cancer (NSCLC)

  Zhang, J. (PI), Chang, J. C. (Key Personnel), Heyne, K. (Key Personnel), Niravath, P. A. (Key Personnel) & Singh, M. (Key Personnel)

  Project: Clinical Trial

• The Effect of Semaglutide in Subjects with Non-cirrhotic Non-alcoholic Steatohepatitis (NASH)

  Victor, III, D. W. (PI) & Kodali, S. (Key Personnel)

  Project: Clinical Trial

• A Study to Assess the Antitumor Activity and Safety of IMAB362 in Combination With Nab-Paclitaxel and Gemcitabine (Nab-P + GEM) as First Line Treatment in Subjects With Claudin 18.2 (CLDN18.2) Positive, Metastatic Pancreatic Adenocarcinoma

  Abdelrahim, M. (PI), Chang, J. C. (Key Personnel), Heyne, K. (Key Personnel), Niravath, P. A. (Key Personnel), Singh, M. (Key Personnel) & Zhang, J. (Key Personnel)

  Project: Clinical Trial

• A Phase 1/2 Open-Label, Ascending Dose, Multicenter Study to Evaluate the Safety and Preliminary Efficacy of AVB-101 administered by Bilateral Intrathalamic Infusion in Subjects with Frontotemporal Dementia With Progranulin Mutations (FTD-GRN)

  Masdeu, J. C. (PI) & Pascual, B. (Key Personnel)

  Project: Clinical Trial

• PALbociclib CoLlaborative Adjuvant Study: A Randomized Phase III Trial of Palbociclib With Standard Adjuvant Endocrine Therapy Versus Standard Adjuvant Endocrine Therapy Alone for Hormone Receptor Positive (HR+) / Human Epidermal Growth Factor Receptor 2

  Niravath, P. A. (PI), Chang, J. C. (Key Personnel), Heyne, K. (Key Personnel) & Singh, M. (Key Personnel)

  Project: Clinical Trial

• Impact of Past Traumatic Load on Physiological Markers During Pregnancy: A Machine Learning Approach

  Project: Clinical Trial

• Universal Psychological Intervention During the Prenatal Period

  Project: Clinical Trial

• A Long-Term Registry of Humira® (Adalimumab) in Patients With Moderately to Severely Active Ulcerative Colitis (UC)

  Abraham, B. P. (PI)

  Project: Clinical Trial

• A Phase 3, Randomized, Open-label Study to Evaluate Perioperative Enfortumab Vedotin Plus Pembrolizumab (MK-3475) Versus Neoadjuvant Gemcitabine and Cisplatin in Cisplatin-eligible Participants With Muscle-invasive Bladder Cancer (KEYNOTE-B15 / EV-304)

  Satkunasivam, R. (PI), Singh, M. (Key Personnel) & Zhang, J. (Key Personnel)

  Project: Clinical Trial

• Phase II Open Label, Study of IMMU-132 in Metastatic Urothelial Cancer After Failure of Platinum-Based Regimen or Anti-PD-1/ PD-L1 Based Immunotherapy

  Abdelrahim, M. (Key Personnel), Chang, J. C. (Key Personnel), Heyne, K. (Key Personnel), Niravath, P. A. (Key Personnel) & Singh, M. (Key Personnel)

  Project: Clinical Trial

• A Phase 3, Double-Blind, Randomized, Placebo-Controlled, Parallel-Group, 27-Week Trial to Evaluate the Efficacy, Safety, and Tolerability of Two Fixed Doses of Tavapadon in Early Parkinson's Disease (TEMPO-1 TRIAL)

  Ondo, W. G. (PI) & Waln, O. (Key Personnel)

  Project: Clinical Trial

• Development of Artificial Intelligence Tools for Cardiac PET Workflow, Diagnosis, and Prognosis

  Al-Mallah, M. (PI)

  Project: Clinical Trial

• A Randomized, Double-Blind, Phase III Trial of Paclitaxel/Trastuzumab/Pertuzumab With Atezolizumab or Placebo in First-Line HER2-Positive Metastatic Breast Cancer

  Niravath, P. A. (PI) & Chang, J. C. (Key Personnel)

  Project: Clinical Trial

• Clinical Phase Ib/II Trial of L-NMMA Plus Docetaxel in the Treatment of Refractory Locally Advanced or Metastatic Triple Negative Breast Cancer Patients

  Niravath, P. A. (PI), Beinart, G. (Key Personnel) & Singh, M. (Key Personnel)

  Project: Clinical Trial

• Global Utilization and Registry Database for Improved Preservation of Donor Livers

  Saharia, A. (PI), Ghobrial, R. M. (Key Personnel), Hobeika, M. J. (Key Personnel) & Mobley, C. M. (Key Personnel)

  Project: Clinical Trial

• Modifying the inpatient environment to reduce the incidence and burden of delirium among hospitalized older adults (≥70 years)

  Vahidy, F. S. (PI), Agarwal, K. S. (Key Personnel) & Taffet, G. (Key Personnel)

  Project: Clinical Trial

• Mechanical stiffness of lung cancer and healthy tissues

  Kim, M. P. (PI), Chan, E. Y. (Key Personnel) & Chihara, R. (Key Personnel)

  Project: Clinical Trial

• Envarsus XR IIS

  Gaber, A. O. (PI) & Knight, R. J. (Key Personnel)

  Project: Clinical Trial

• Phase III Trial of Docetaxel vs. Docetaxel and Radium-223 for Metastatic Castration-Resistant Prostate Cancer (mCRPC)

  Heyne, K. (Key Personnel), Singh, M. (Key Personnel) & Zhang, J. (Key Personnel)

  Project: Clinical Trial

• A Phase II Randomized, Open-label, Multi-center Study of the Safety and Efficacy of IMCgp100 Compared With Investigator Choice in HLA-A*0201 Positive Patients With Previously Untreated Advanced Uveal Melanoma

  Abdelrahim, M. (Key Personnel), Heyne, K. (Key Personnel), Niravath, P. A. (Key Personnel) & Singh, M. (Key Personnel)

  Project: Clinical Trial

• Study of Sasanlimab (PF-06801591) in Combination With Bacillus Calmette-Guerin (BCG) in Participants With High-Risk Non-Muscle Invasive Bladder Cancer (CREST)

  Satkunasivam, R. (PI), Singh, M. (Key Personnel) & Zhang, J. (Key Personnel)

  Project: Clinical Trial

• A Phase 3, Multicenter, Randomized, Controlled, Open-Label, Assessor-Blinded Study to Evaluate the Efficacy and Safety of Inhaled Isoflurane Delivered via the Sedaconda ACD-S Compared to Intravenous Propofol for Sedation of Mechanically Ventilated Intensive Care Unit Adult Patients (INSPiRE-ICU1)

  Faisal, H. (PI), Dhala, A. (Key Personnel), Masud, F. N. (Key Personnel), Mobley, C. M. (Key Personnel), Moore, L. W. (Key Personnel), Rizk, E. (Key Personnel) & Sanchez Leon, R. (Key Personnel)

  Project: Clinical Trial

• An Open-label Phase II Study to Investigate the Efficacy, Safety, and Pharmacokinetics of Tirabrutinib in Patients With Primary Central Nervous System Lymphoma (PCNSL)

  Pingali, S. R. (PI), Ganguly, S. (Key Personnel) & Shah, S. (Key Personnel)

  Project: Clinical Trial

• Enabling Access to Prehabilitation for Kidney Transplant Candidates who are Frail

  Dhala, A. (PI) & Yi, S. (Key Personnel)

  Project: Clinical Trial

• Surgical Irrigation with Synergistic Surgical Solution (BIASURGE) Application Impact on the Reduction of Groin Wound Complications in Vascular Surgery Wounds

  Rahimi, M. (PI), Le, L. (Key Personnel), Lumsden, A. B. (Key Personnel), Peden, E. K. (Key Personnel) & Roy, T. (Key Personnel)

  Project: Clinical Trial

• Phase I Trial of Atezolizumab and Interleukin-12 Gene Therapy in Metastatic Non-Small Cell Lung Cancer With Progression on First-Line Immunotherapy With or Without Chemotherapy

  Zhang, J. (PI), Chan, E. Y. (Key Personnel), Gibbs, J. M. (Key Personnel), Heyne, K. (Key Personnel), Kim, M. P. (Key Personnel), Rudkovskaia, A. A. (Key Personnel) & Singh, M. (Key Personnel)

  Project: Clinical Trial

• Mitochondrial function in symptomatic chronic COVID-19 patients COVID-19 Associated Mitochondria Functional Changes in Subjects with Post-Acute Sequelae of SARS-CoV-2 Infections (PASC)

  Hamilton, D. J. (PI), Kansara, A. (Key Personnel) & Youssef, J. G. (Key Personnel)

  Project: Clinical Trial

• VAS-Zenith p-Branch Pivotal Study

  Lumsden, A. B. (PI) & Rahimi, M. (Key Personnel)

  Project: Clinical Trial

• HF-DT PAS Apogee Registry - PSR-MCS

  Suarez, E. E. (PI), Bhimaraj, A. (Key Personnel), Fida, N. (Key Personnel), Guha, A. (Key Personnel), Hussain, I. (Key Personnel), Kassi, M. (Key Personnel) & Kim, J. H. (Key Personnel)

  Project: Clinical Trial

• HF-SHORE CareDx

  Kim, J. H. (PI), Bhimaraj, A. (Key Personnel), Gorthi, J. R. (Key Personnel), Guha, A. (Key Personnel), Hussain, I. (Key Personnel), Kassi, M. (Key Personnel) & Yousefzai, R. (Key Personnel)

  Project: Clinical Trial

• A Prospective Registry Study to Evaluate the Effect of the DCISionRT Test on Treatment Decisions in Patients With DCIS Following Breast Conserving Therapy

  Templeton, S. (PI), Arentz, C. (Key Personnel), Chang, J. C. (Key Personnel), Darcourt, J. (Key Personnel), Dubrovsky, E. (Key Personnel), Haque, W. M. (Key Personnel), Heyne, K. (Key Personnel), Morgan, P. B. (Key Personnel), Niravath, P. A. (Key Personnel) & Singh, M. (Key Personnel)

  Project: Clinical Trial

• Multicenter Phase II Trial of Durvalumab (MEDI4736) With Trastuzumab and Pertuzumab Combination in HER2-Enriched and HER2-Amplified Breast Cancer (DTP Trial)

  Chang, J. C. (PI), Arentz, C. (Key Personnel), Mai, H. P. (Key Personnel), Niravath, P. A. (Key Personnel) & Sun, K. (Key Personnel)

  Project: Clinical Trial

• HF - PROACTIVE-HF Trial

  Yousefzai, R. (PI), Bhimaraj, A. (Key Personnel), Gorthi, J. R. (Key Personnel), Hussain, I. (Key Personnel), Kassi, M. (Key Personnel), Kim, J. H. (Key Personnel) & Lin, C. H. (Key Personnel)

  Project: Clinical Trial

• GOG0274The OUTBACK Trial

  Kamat, A. A. (PI), Butler, E. B. (Key Personnel), Farach, A. M. (Key Personnel), Morgan, P. B. (Key Personnel), Singh, M. (Key Personnel) & Suri, A. (Key Personnel)

  Project: Clinical Trial

• An Open-Label, Controlled, Randomized Phase 3 Trial Evaluating 12-Month Kidney Function in Highly Sensitized (cPRA =99.9%) Kidney Transplant Patients with Positive Crossmatch Against a Deceased Donor, Using Imlifidase with Standard of Care

  Gaber, A. O. (PI), Knight, R. J. (Key Personnel) & Yi, S. (Key Personnel)

  Project: Clinical Trial

• GOG-0281

  Kamat, A. A. (PI), Singh, M. (Key Personnel) & Suri, A. (Key Personnel)

  Project: Clinical Trial

• SURTAVI

  Kleiman, N. (PI), Faza, N. (Key Personnel), Goel, S. (Key Personnel), Little, S. H. (Key Personnel) & Reardon, M. J. (Key Personnel)

  Project: Clinical Trial

• A Randomized Phase III Trial of Radiation Therapy and Cisplatin Alone or in Combination With Intravenous Triapine in Women With Newly Diagnosed Bulky Stage IB2, Stage II, IIIB, or IVA Cancer of the Uterine Cervix or Stage II-IVA Vaginal Cancer (NRG-GY006)

  Zaid, T. (PI), Butler, E. B. (Key Personnel), Farach, A. M. (Key Personnel), Haque, W. M. (Key Personnel), Kamat, A. A. (Key Personnel), Morgan, P. B. (Key Personnel), Shadle, K. M. (Key Personnel), Shkedy, C. (Key Personnel), Singh, M. (Key Personnel) & Suri, A. (Key Personnel)

  Project: Clinical Trial

• Retrospective/Multi-modal AI to Predict Cardiovascular Risk/Dept Funded

  Al-Kindi, S. G. (PI) & Nasir, K. (Key Personnel)

  Project: Clinical Trial

• Assessing the Prognostic Value of Cardiac Magnetic Resonance (CMR) for Heart Transplant Recipients

  Yousefzai, R. (PI), Bhimaraj, A. (Key Personnel), Gaber, A. O. (Key Personnel), Guha, A. (Key Personnel), Kassi, M. (Key Personnel), Kim, J. H. (Key Personnel), Martin, C. M. (Key Personnel) & Shah, D. J. (Key Personnel)

  Project: Clinical Trial

• Pivotal, Randomized, Open-label Study of Tumor Treating Fields (TTFields, 150kHz) Concomitant With Gemcitabine and Nab-paclitaxel for Front-line Treatment of Locally-advanced Pancreatic Adenocarcinoma

  Abdelrahim, M. (PI), Chang, J. C. (Key Personnel), Heyne, K. (Key Personnel), Niravath, P. A. (Key Personnel), Singh, M. (Key Personnel) & Templeton, S. (Key Personnel)

  Project: Clinical Trial

• VAS-Gore Tambe AAA 17-01

  Lumsden, A. B. (PI) & Rahimi, M. (Key Personnel)

  Project: Clinical Trial

• Retrospective review of clinical outcomes of interventions in patients with venous disease.

  Peden, E. K. (PI) & Garami, Z. (Key Personnel)

  Project: Clinical Trial

• CMR for COVID Patients

  Shah, D. J. (PI), Graviss, E. A. (Key Personnel), Malahfji, M. (Key Personnel) & Nasir, K. (Key Personnel)

  Project: Clinical Trial

• WIP scans: MRI technology improvement

  Martin, D. R. (PI), Gupta, N. (Key Personnel), Karmonik, C. (Key Personnel) & Miles, B. J. (Key Personnel)

  Project: Clinical Trial

• A Phase II Trial of Ribociclib (LEE011) Plus Letrozole in Women With Recurrent Low-Grade Serous Carcinoma of the Ovary, Fallopian Tube or Peritoneum (GOG-3026)

  Kamat, A. A. (PI), Singh, M. (Key Personnel), Suri, A. (Key Personnel) & Zaid, T. (Key Personnel)

  Project: Clinical Trial

• ACURATE IDE: Safety and Effectiveness Study of ACURATE Valve for Transcatheter Aortic Valve Replacement

  Kleiman, N. (PI), Faza, N. (Key Personnel), Goel, S. (Key Personnel), Little, S. H. (Key Personnel), Reardon, M. J. (Key Personnel) & Volpi, J. J. (Key Personnel)

  Project: Clinical Trial

• DiamondTemp System for the Treatment of Persistent Atrial Fibrillation (Diamond-AFII)

  Valderrábano, M. (PI), Dave, A. (Key Personnel), Lador, A. (Key Personnel), Mathuria, N. (Key Personnel) & Schurmann, P. A. (Key Personnel)

  Project: Clinical Trial