Department of Medicine

Projects

Projects per year 2007 2021 2022 2023 2024 2045

• 15 Not started
• 46 Finished
• 55 Active

Projects per year

Search results

• Active

  Prospective, multicentre study to validate the GastroIntestinal Dysfunction Score (GIDS) and describe prevalence, outcomes, and management of phosphate disorders in intensive care patients

  Sanchez Leon, R. & Moran, D.

  6/12/24 → …

  Project: Clinical Trial

• LATinx 'N of one' in PAH Trials (LATN PAT)

  Sahay, S.

  6/3/24 → …

  Project: Clinical Trial

• Pilot_Vent_Free_Liberate_Medical

  Gotur, D. B.

  5/22/24 → …

  Project: Clinical Trial

• A Randomized, Sham Controlled, Double-blinded, Multi-center Trial to Evaluate the Efficacy of the VentFree Respiratory Muscle Stimulator to Assist Ventilator Weaning in Critically Ill Patients.

  Gotur, D. B.

  4/17/24 → 4/16/29

  Project: Federal Funding Agencies

• Structural and functional alterations in mitochondria of patients with multi-organ injury and sepsis

  Gotur, D. B., Hamilton, D. J. & Mylonakis, E.

  4/3/24 → …

  Project: Clinical Trial

• Dysfunctional High Density Lipoprotein Free Cholesterol Bioavailability and Atherogenesis

  Pownall, H. J., Gillard, B. K., Nasir, K., Patel, K. V. & Rosales, C.

  3/21/24 → …

  Project: Clinical Trial

• Observational study to compare the effectiveness of Ceftazidime-Avibactam versus Ceftolozane-Tazobactam for multidrug-resistant Pseudomonas aeruginosa infections in the United States (CACTUS)

  Miller, W. R.

  3/18/24 → 3/17/34

  Project: Non Profit

• SciClone-Thymalfasin (thymosin alpha 1; Ta1) as an enhancer of vaccine response among older adults receiving booster doses of COVID-19

  Mylonakis, E. & Gotur, D. B.

  3/6/24 → …

  Project: Clinical Trial

• Endoscopic sleeve gastroplasty (ESG) for the treatment of obesity

  McCarty, T. R. & Tariq, N.

  2/9/24 → …

  Project: Clinical Trial

• A Phase III, adjudicator-blinded, randomised study to evaluate the efficacy and safety of treatment with olorofim versus treatment with AmBisome® followed by standard of care (SOC) in patients with invasive fungal disease (IFD) caused by Aspergillus species

  Grimes, K. A., Lin, J., Malik, A. I. & Nigo, M.

  11/16/23 → …

  Project: Clinical Trial

• Specialty societies advancing adult immunizations in patients with diabetes

  Sadhu, A.

  10/1/23 → 9/30/25

  Project: Federal Funding Agencies

• A transformative platform to combat antibiotic resistant bacteria.

  Mylonakis, E.

  9/26/23 → 9/25/28

  Project: Federal Funding Agencies

• PK-RNN-V - Deep-Learning Based Pharmacokinetic Model for Vancomycin

  Nigo, M.

  9/21/23 → 7/31/28

  Project: Federal Funding Agencies

• De-labeling Penicillin Allergy in an Academic Medical Center ? A Quality Improvement Initiative

  Motazedi, T.

  9/1/23 → 12/31/24

  Project: Non Profit

• Clinical Impact of the Cefazolin Inoculum Effect

  Arias, C. A.

  6/5/23 → 5/31/28

  Project: Federal Funding Agencies

• RECOVER-VITAL: A Platform Protocol for Evaluation of Interventions for Viral Persistence, Viral Reactivation, and Immune Dysregulation in Post-Acute Sequelae of SARS-CoV-2 Infection (PASC)

  Mylonakis, E.

  6/1/23 → 12/31/26

  Project: Federal Funding Agencies

• A Multicenter, Adaptive, Randomized, Controlled Trial Platform To Evaluate Safety and Efficacy of Strategies and Treatments for Hospitalized Patients with Respiratory Infections (STRIVE)

  Mylonakis, E.

  5/22/23 → 3/31/25

  Project: Non Profit

• MRWeight: Medical Residents Learning Weight Management Counseling Skills -- A Multi-Modal, Technology-Assisted, Spaced Education Program

  Awar, M.

  5/2/23 → 2/29/28

  Project: Federal Funding Agencies

• Human Atherogenesis with Underlying Dysfunctional HDL-Free Cholesterol

  Pownall, H. J.

  4/4/23 → 2/28/27

  Project: Federal Funding Agencies

• A Study Comparing Talquetamab in Combination With Daratumumab or in Combination With Daratumumab and Pomalidomide Versus Daratumumab in Combination With Pomalidomide and Dexamethasone in Participants With Relapsed or Refractory Multiple Myeloma

  Ganguly, S., Mai, H. P., Petkova, J., Pingali, S. R. & Shah, S.

  3/30/23 → …

  Project: Clinical Trial

• Subproject 2: Identification of Pathways that Can be Targeted for the Development of Novel Therapies for MRSA

  Mylonakis, E.

  3/1/23 → 1/31/27

  Project: Federal Funding Agencies

• Emergence of TonB-dependent receptor mediated cefiderocol resistance among multidrug-resistant (MDR) Pseudomonas aeruginosa clinical isolates.

  Miller, W. R.

  1/20/23 → 12/31/24

  Project: Federal Funding Agencies

• Atezolizumab and Bevacizumab Pre-Liver Transplantation for Patients with Hepatocellular Carcinoma Beyond Milan Criteria: A Feasibility Study

  Abdelrahim, M., Connor, A. A., Ghobrial, R. M., Gibbs, J. M., Graviss, E. A., Gupta, N., Kodali, S., Mobley, C. M., Moore, L. W., Rizk, E., Saharia, A., Singh, M. & Victor, III, D. W.

  1/18/23 → …

  Project: Clinical Trial

• 2023 ACS Prevention & Screening Project Recruitment Colon Cancer

  Neal, R.

  1/1/23 → 12/31/24

  Project: Non Profit

• A Randomized, Sham Controlled, Double-blinded, Multi-center Trial to Evaluate the Efficacy of the VentFree Respiratory Muscle Stimulator to Assist Ventilator Weaning in Critically Ill Patients.

  Gotur, D. B.

  9/30/22 → 3/29/26

  Project: Federal Funding Agencies

• Elucidating the Biology of Cardiovascular Risk in Hemodialysis Patients Using Proteomics.

  Shafi, T.

  9/7/22 → 4/30/25

  Project: Federal Funding Agencies

• Vaccination Responses in Lung Transplant Recipients

  Huang, H. J.

  8/5/22 → 7/31/27

  Project: Federal Funding Agencies

• POR and Training Program on Multidrug-Resistant Organisms

  Arias, C. A.

  7/1/22 → 6/30/26

  Project: Federal Funding Agencies

• Combining Transcutaneous Spinal Stimulation and Exoskeleton Training in the Rehabilitation of Spinal Cord Injury.

  Sayenko, D., Kaldis, T. & Tabatabai, L. S.

  6/20/22 → …

  Project: Clinical Trial

• VENOUS: A translational study of enterococcal bacteremia

  Arias, C. A.

  6/1/22 → 5/31/25

  Project: Federal Funding Agencies

• Early Detection of Hepatocellular Carcinoma - Renewal Submission

  Victor, III, D. W.

  4/21/22 → 2/28/27

  Project: Federal Funding Agencies

• A Randomized Trial of Ultrasound-facilitated, Catheter-directed, Thrombolysis Versus Anticoagulation for Acute Intermediate-high Risk Pulmonary Embolism: The Higher-risk Pulmonary Embolism Thrombolysis Study

  Bartra, H.

  2/10/22 → …

  Project: Clinical Trial

• A multi-center, randomized, 36-month, parallel group, non-inferiority, phase III study to compare the effectiveness of 500 mcg QD or alternate regimen of roflumilast (Daliresp) therapy versus 250 mg QD, 500 mg QD three times per week, or alternate regime

  Folz, R. J.

  12/1/21 → 5/31/25

  Project: Federal Funding Agencies

• A multi-center, randomized, 36-month, parallel group, non-inferiority, phase III study to compare the effectiveness of 500 mcg QD or alternate regimen of roflumilast (Daliresp) therapy versus 250 mg QD, 500 mg QD three times per week, or alternate regime

  Folz, R. J.

  12/1/21 → 5/31/25

  Project: Federal Funding Agencies

• RiOciguAt UseRs Registry The ROAR registry

  Sahay, S. & Safdar, Z.

  11/30/21 → …

  Project: Clinical Trial

• A Clinical Evaluation of the RheOx Bronchial Rheoplasty System for the Treatment of the Symptoms of Chronic Bronchitis in Adult Patients With COPD

  Kopas, L. & Doerr, C. H.

  11/8/21 → …

  Project: Clinical Trial

• Gossamer_GB002-2102_Phase 2 OLE_Pulmonary Arterial Hypertension An Open-label Extension Study Evaluating the Long-term Safety and Efficacy of Oral Inhalation of GB002 for the Treatment of WHO Group 1 Pulmonary Arterial Hypertension (PAH)

  Sahay, S. & Safdar, Z.

  9/15/21 → …

  Project: Clinical Trial

• Targeting Inflammation and Alloimmunity in Lung Transplant Recipients with Clazakizumab

  Huang, H. J.

  9/14/21 → 6/30/25

  Project: Federal Funding Agencies

• Dynamics of Colonization and Infection by Multidrug-resistant Pathogens in Immunocompromised and Critically Ill Patients (DYNAMITE)

  Arias, C. A.

  9/1/21 → 7/31/25

  Project: Federal Funding Agencies

• Phase 3_Sotatercept_ Pulmonary Arterial Hypertension _Acceleron A011-12 SOTERIA A Long-term Follow-up Study of Sotatercept for PAH Treatment

  Safdar, Z. & Sahay, S.

  8/5/21 → …

  Project: Clinical Trial

• S100A4 mediated immune suppression in GBM

  Yun, K. & Xu, S.

  4/1/21 → 1/31/26

  Project: Federal Funding Agencies

• A Phase II and Biomarker Study of Dual VEGF/PD-L1 Blockade in Neoadjuvant Setting in Resectable Hepatocellular Carcinoma Patients

  Ghobrial, R. M., Abdelrahim, M. & Kodali, S.

  4/1/21 → 3/31/26

  Project: Federal Funding Agencies

• CHEST CYTOSTORM study

  Gotur, D. B.

  3/8/21 → …

  Project: Clinical Trial

• Nanotechnology-based targeting of breast cancer liver metastases

  Godin, B., Chen, S., Niravath, P. A., Rosato, R. R. & Xu, S.

  3/1/21 → 2/28/25

  Project: Federal Funding Agencies

• N/A

  Dacha, S. & Quigley, E. M.

  12/2/20 → …

  Project: Clinical Trial

• Defining the altered FUS-PARP-1-DNA Ligase III axis and its implications to nuclear and mitochondrial genome damage response in Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD)

  Hegde, M., Hamilton, D. J., Horner, P. J. & Mitra, J.

  4/15/20 → 3/31/25

  Project: Federal Funding Agencies

• A Pilot Randomized Controlled Trial of De Novo Belatacept-Based Immunosuppression in Lung Transplantation

  Huang, H. J.

  3/26/20 → 3/25/45

  Project: Non Profit

• AOCT - Zephyr Valve Registry ZEVR

  Kopas, L.

  2/3/20 → …

  Project: Clinical Trial

• Atheroprotection via Reduced Plasma High Density Lipoprotein-Free Cholesterol Bioavailability

  Pownall, H. J., Rosales, C. & Gillard, B. K.

  12/1/19 → 11/30/24

  Project: Federal Funding Agencies

• Study ROR-PH-303, ADVANCE EXTENSION, is an open-label extension (OLE) study for participants with WHO Group 1 PAH who have participated in another Phase 2 or Phase 3 study of ralinepag

  Safdar, Z. & Sahay, S.

  5/17/19 → …

  Project: Clinical Trial